Biomedical subjects
Publications and source records attributed to D T Yew.
The retinas of 4 fishes (Periophthalmus chrysopilos, Scorpaenoides marmoratus, Nemipterus bathybins, Taius tumifrons) were analysed. Rods were found to increase with depth but twin cones were not found to descrease with depth. A regional difference was also observed in the distribution of these elements in the retinas.
The development of the optic tectum and the main nuclei of the visual pathways were studied in the quail and correlated with retinal development. The lateral geniculate nuclei began to establish by the 8th day of ineubation and the optic fibre reached the optic tectum by the 10th day, a time when the retina acquired its inner segments. By the 14th day when the retina became fully development, the cytological architecture in the tectum and the appearing of the other visual nuclei were completed.
The forms of shedding of outer segment disks were observed in the retinas of albino rats. Different forms included those coming from the tips and sides of the outer segments and many other variations. All these detached disks began to undergo morphological changes before being taken into the pigment epithelium.
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Lens fiber lesions after laser irradiation were studied in the albino rats. Loss of cytoplasmic contrast, pulling apart of intercellular cell junctions and increase of intracellular vesicles were observed.
The influence on the development of the outer segments of the rat retina of far red and red light in different sequences was investigated. The far red treatment appeared to be dominating, and for animals treated with far red light first, further treatment of red light could not bring the outer segment growth back to normal. The treatments also initiated different dopamine uptakes in the retinas.
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The development of the pecten oculi was studied in the chick (Gallus gallus). The initial development commenced on the 9th day of incubation. The pigment cells in the pecten were derived from the pigment epithelium of the retina and the connective tissue and blood vessels were continuous with those of the choroid.
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Labelled uridine uptake was studied in the control and 6-hydroxydopamine-treated retina by autoradiography. Decrease labelled uridine uptake was detected in the 6-hydroxydopamine-treated retinas.
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The effect of laser on the retinas and brains of the neonatal and adult rodents were studied by employing monoamine oxidase histochemistry and K+ concentration study. No significant difference was found in the neonatal retinas and brains after irradiation when compared with control. But significant differences were found in the retinas and brains of the adult rodents after irradiation.