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Biomedical subjects

D Schumann

Publications and source records attributed to D Schumann.

At least 91 records · Page 5Linked to original sources

Leukoplakia induced by repeated deposition of formalin in rabbit oral mucosa. Long-term experiments with a new "oral tank".

Rabbits were exposed repeatedly to formalin irritation using a new oral tank which allows a chronical contact with the oral mucosa. In long-term experiments (11 months) a preneoplastic unrest of the epithelium with dyskeratosis could be produced. This new model of "oral tank" can be used for soluble and insoluble test substances for analyzing pathogenetic processes in the oral cavity.

Animals↗

[Bacteriological control of surgical hand disinfection by means of selected agents].

Three techniques of surgical hand disinfection (use of Fesia-cito, utilization of a Wofasteril-alcohol-water mixture and a modified Fürbringer-Ahlfeld method) were verified with regard to the reduction in the bacterial count of the non-infected day-hand. The Wofasteril-alcohol-water mixture caused a 99.8% reduction in the bacterial count on the right hand, and a 99.9% reduction on the left hand. The data obtained with Fesia-cito were 80.2% and 66.6% respectively. With the modified Fürbringer-Ahlfeld method the reduction in the bacterial count was 96.9% and 98.6% respectively. The authors emphasize the claim for the principle of non-infection in the field of maxillofacial surgery and recommended to exercise reserve in regard to the routine use of Fesia-cito for surgical hand disinfection.

Alcohols↗

[Resistance to chemotherapy of aerobic bacteria from nonspecific odontogenic infections].

Germs in patients suffering from nonspecific odontogenous infections described in a previous paper were analysed with regard to their resistance to chemotherapy (1964 to 1971). At the same time it was discovered that in the bacteria groups: staphyloccocus aureus, streptococci and pneumococci and enterobacteriaceae plus pseudomonas (344 strains) their sensitivity to penicillin, streptomycin, chloramphenicol, oxytetracyclin, erythromycin, polymyxin B and nifurantin varied in several and significant ways. Significant changes were established in the resistance of staphylococcus aureus to all the potentially effective antibiotics, while from 1969 to 1971 the strains with the least resistance appeared. In the 1970 to 1971 period strepto- and pneumococci showed insensitivity to penicillin and streptomycin more frequently than before. From 1969 to 1971 entero-bacteriaceae and pseudomonas also showed evidence of increasing loss of sensitivity to chloramphenicol and oxytetracyclin, whereas the frequency of strains resistant to polymyxin B and nifurantine diminished. The findings are being discussed.

Anti-Bacterial Agents↗

[Bacteriological findings in materials from patients with nonspecific odontogenic infections].

The results of bacteriological studies made between 1964 and 1971 by workers at the Varia Laboratory, Institute of Medical Microbiology on 767 patients treated at the Clinic of Gnathofacial Surgery, Department of Medicine, Friedrich Schiller University at Jena, are evaluated. The testees (x=275) were included in groups with specific diagnoses, and a breakdown was made according to the detection of aerobic pus-forming germs. Gram-positive cocci were detected in 92% of the cases and their pathogenetic representatives, 76,5% of the cases. Rodshaped germs (Enterobacteriaceae, Pseudomonas) were observed only in 37,9% of the cases. Staphylococcus aureus, which accounted for 62,5%, was the most frequently observed species. It was followed, in order of frequency of detection, by greening streptococci and Staphylococcus epidermidis. Monoinfection was far more frequently observed than multi-infection. Also, the problems associated with the differentiation of streptococci are pointed out since other investigators found streptococci to be the most frequent agents producing odontogenic infections.

Bacterial Infections↗

The renal donor.

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Adolescent↗