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Biomedical subjects

D Resnick

Publications and source records attributed to D Resnick.

At least 685 records · Page 38Linked to original sources

Radiographic features of gout in the foot.

The radiographic findings associated with gout have been widely reported since their initial description by Huber in 1896 (1). This review will describe the characteristic alterations associated with involvement of the foot by gout, as well as several less common manifestations of the disease at this site. Brief consideration is also given to the radiographic differential diagnosis of gouty arthritis affecting the foot.

Arthritis↗

Diagnostic imaging approach to calcaneal fractures.

An overview of the diagnostic imaging methods important to the accurate detection and characterization of calcaneal fractures is presented. Conventional radiography and tomography, as well as computed tomography with multiplanar reformation and three-dimensional image reconstruction, are discussed with reference to specific types of injuries.

Calcaneus↗

Axial computed tomographic anatomy of the foot: Part III. Forefoot.

Cross-sectional osseous and soft tissue anatomy of the human forefoot as demonstrated by high resolution computed tomography (CT) is described. This report serves an important baseline function because CT may be useful for the evaluation of a variety of forefoot disorders in the clinical setting.

Arteries↗

Computed tomography of podiatric disorders: a review.

Computed tomography has become invaluable in diagnosing various disorders of the foot and ankle. Because it provides a three-dimensional range of views of both soft tissue and osseous anatomy and depicts the spatial relationship between structures, it has many advantages over conventional methods. With the use of computed tomography, it is now possible to view the foot in a variety of planes by placing the patient in various positions.

Ankle↗

Magnetic resonance imaging of podiatric disorders: a pictorial essay.

Cross-sectional imaging techniques, including computed tomography and magnetic resonance imaging, have become increasingly important in the evaluation of a variety of podiatric disorders. Illustrative cases are used to emphasize the relative merits of the two methods. Generally, magnetic resonance imaging is superior for soft tissue and bone marrow disease, whereas computed tomography affords optional depiction of cortical bone abnormalities.

Foot Diseases↗

Magnetic resonance imaging of the foot: technical aspects.

The technical considerations relevant to magnetic resonance imaging of the foot are discussed. Case presentations underscore the importance of multiple image weighting for optimal identification and characterization of soft tissue pathology.

Foot↗

Axial computed tomographic anatomy of the foot. Part I: Hindfoot.

Osseous and soft tissue anatomy of the human hindfoot is presented as visualized on high-resolution axial computed tomography (CT). Radiologic-pathologic correlation with the use of a cadaver specimen and contiguous CT sections 1.5 mm. thick was performed for structural identification. The foot of a healthy senior citizen was scanned by using 5.0-mm. slice thickness. Because of the proven and potential capabilities of CT in the diagnosis of hindfoot disorders, this report serves as an important standard for comparison with clinical studies.

Calcaneus↗

Axial computed tomographic anatomy of the foot. Part II: Midfoot.

Osseous and soft tissue anatomy of the human midfoot is presented as visualized on high resolution axial computed tomography (CT). Because of the proven and potential capabilities of CT in the diagnosis of midfoot disorders, this report serves as an important standard for comparison with clinical studies.

Calcaneus↗

Investigation of a new arthrographic contrast agent: Iotrol.

A new nonionic dimer (Iotrol; Schering AG) and diatrizoate meglumine-diatrizoate sodium (Renografin-60; Squibb) were compared as arthrographic agents by injecting these substances into the knees of rabbits. Three experienced arthrographers judged the image quality produced by Iotrol to be superior to that of Renografin-60. Following animal sacrifice, histologic examination of the synovium revealed a significant difference in the inflammatory response evoked by the contrast agents: Iotrol caused less inflammation. In a second group of rabbits, methylprednisolone was subcutaneously injected 24 hours before the arthrographic studies. The methylprednisolone significantly reduced the inflammation in the Renografin-60 subgroup when compared with the nonmedicated counterparts. No significant effect was noted in a like comparison with Iotrol. In addition, the administration of methylprednisolone led to a deterioration of the radiographic images. Based upon our data, we believe Iotrol is superior to Renografin-60 as an arthrographic agent.

Animals↗

Extensive spinal osteophytosis as a risk factor for heterotopic bone formation after total hip arthroplasty.

Observations on 54 patients present circumstantial evidence of a relationship between an underlying spinal ossifying diathesis and the heterotopic bone formation following total hip arthroplasty. This relationship should be investigated in a larger patient population to determine whether a spine-hip diathesis exists and could account for some patients with this complication. If it can be statistically substantiated, spinal roentgenograms may provide a preoperative screening procedure for the identification of "a population at risk" of heterotopic bone formation who might benefit from a prophylactic medical regimen.

Adult↗

Analysis of auranofin as a rheumatoid remitting agent.

To assess the therapeutic potential of Auranofin (AF), we examined the results of 7 early short term clinical trials involving 104 rheumatoid arthritis (RA) patients; radiographic analyses were performed on 16 of these patients followed for 4 years. This agent suppressed RA in 2/3-3/4 of patients followed for periods up to 1 year; thereafter emergence of RA activity occurred despite maintenance medication. Serious toxicity was nonexistent. Radiographic analyses indicated a minority of patients may have arrested disease demonstrated by lack of erosion progression. Thus, AF has a similar therapeutic profile to conventional chrysotherapy but the drug is more useful because of absence of serious toxicities.

Arthritis, Rheumatoid↗