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Biomedical subjects

D Resnick

Publications and source records attributed to D Resnick.

At least 397 records · Page 22Linked to original sources

Hand radiographic changes in patients with primary and secondary Sjögren's syndrome.

Unselected hand radiographs from 37 primary Sjögren's syndrome patients (pSS), 19 patients with rheumatoid arthritis (RA) and Sjögren's syndrome (secondary SS) and 29 patients with RA only were evaluated blind by osteoradiologists, using reference radiographs for scoring joint space narrowing and erosion at the proximal interphalangeal joints, the metacarpophalangeal joints and the wrists. A history of arthralgias and/or arthritis of the above joints was taken from the patients charts. It is shown that pSS patients suffer from transient episodes of arthralgias and/or arthritis, while both secondary SS and RA patients had a history of chronic arthritis of the small joints of the hand. Evaluation of the hand radiographs showed that pSS patients exhibited mild joint space narrowing but no erosions, whereas the other two groups of patients presented with more severe joint space narrowing and varying degrees of erosions. Finally, RA patients without SS had more advanced radiographic changes than secondary SS patients. Thus hand X-rays can be used in addition to the previously described clinical differences in the differentiation of primary and secondary SS.

Arthritis, Rheumatoid↗

Plasma cell sclerosis of bone: a spectrum of disease.

We describe the clinical, radiographic, and pathologic manifestations of a group of disorders characterized by osteosclerosis in association with plasmacytic infiltration of bone marrow. These conditions include multiple myeloma, plasma cell granuloma, sternocostoclavicular hyperostosis, the POEMS syndrome (plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes), and chronic symmetric plasma cell osteomyelitis of childhood. Although clinically unrelated in many respects, features shared by these diseases support the existence of a specific factor linking the plasma cell to local osteogenesis.

Adolescent↗

A technique for multiplanar reformation and three-dimensional analysis of computed tomographic data: application to adult hip disease.

A commercially available system which is able to accept input from computed tomographic (CT) or magnetic resonance (MR) scanners was used preoperatively to generate multiplanar reformations (MPR) and three-dimensional (3D) images depicting the osseous morphologic alterations and femoral-acetabular relationships in 25 adult patients with a variety of hip diseases. Polyethylene surface representations of femora and acetabulae were constructed by the 3D-contouring of CT data and were then compared to resected specimens from patients who subsequently underwent total hip arthroplasty. Information provided by this imaging strategy was useful in both selecting and guiding the most appropriate surgical procedure, and the models depicted actual osseous contours with reasonable accuracy. The system employed has distinct advantages over other previously described 3D imaging strategies, which include a menu-driven user-friendly interface, data base access via reference images, 3D sectional analysis, and contour file editing for selective visualization of desired structures.

Acetabulum↗

Computed arthrotomography with multiplanar reformations and three-dimensional image analysis in the evaluation of the cruciate ligaments: preliminary investigation.

The normal cruciate ligaments in patient and cadaver knees were imaged with computed tomography (CT) using a graphic system that allowed reformation of the CT data in multiple planes, as well as three-dimensional display. This imaging format afforded excellent visualization of the cruciate ligaments. When the results were correlated with anatomic findings in sections of the knee from cadavers, the image data were found to be accurate.

Humans↗

Computed tomography with multiplanar reformation and 3-dimensional image analysis in the preoperative evaluation of ischemic necrosis of the femoral head.

Computed tomography (CT) with multiplanar reformation and 3-dimensional image reconstruction were utilized preoperatively to assess the extent of infarction and collapse of the femoral head in 15 patients with ischemic necrosis. Polyethylene models of the diseased femoral heads were constructed from 3-dimensional contouring of CT data, and compared with resected specimens in patients who underwent subsequent total hip arthroplasty. Information provided by this imaging strategy was valuable in both the selection and the planning of the most appropriate surgical procedure, and models were found to represent resected head configurations with reasonable accuracy. CT combined with multiplanar reformation and 3-dimensional analysis may be the optimal preoperative means for evaluating advanced ischemic necrosis involving the femoral head.

Adult↗

Diagnosis of tarsal coalition with computed tomography.

The value of computed tomography in the diagnosis of tarsal coalition is reported in six patients, five with talocalcaneal coalition and one with calcaneonavicular coalition. The examination is technically easy to perform with the patient in the supine position and the knees flexed, and it allows simultaneous visualization of both sides. Because of these features and an ability to distinguish between bony and cartilaginous or fibrous fusion, computed tomography appears to be the method of choice for diagnosis of coalition involving talus and calcaneus. It is less useful in other types of coalition.

Adult↗

Radiology of disorders of the sacroiliac joints.

Differentiation of the many disorders that affect the sacroiliac joints can often be accomplished by attention to radiographic detail. By evaluating the distribution of disease, the presence of erosions and other changes as noted herein, and the course of disease over a period of time, a specific diagnosis can often be made, or at the very least, suggested (Table).

Adult↗

Widespread osteonecrosis of the foot in systemic lupus erythematosus: radiographic and gross pathologic correlation.

A patient with systemic lupus erythematosus required an amputation of the foot related to the presence of vascular disease and infection. Radiographs obtained prior to amputation revealed osteonecrosis in virtually every bone of the foot. Radiographic-pathologic correlation documented this widespread osseous involvement. Although ischemic necrosis of bone is a well-known feature of systemic lupus erythematosus, its localization in the small bones of the foot is rare.

Adult↗

Synovial cysts of the hip joint and iliopsoas bursitis: a spectrum of imaging abnormalities.

Synovium-related soft tissue disease around the hip constitutes a spectrum ranging from isolated iliopsoas bursitis to pure articular synovial herniations without bursal involvement. The clinical, pathologic, and radiographic features of these entities are discussed as they pertain to the variety of underlying disorders which predispose to their occurrence. Nine case reports are utilized to illustrate the variable clinical and radiographic presentations which may be encountered. Based upon these cases as well as those in the literature, an imaging algorithm has been developed which should eliminate unnecessary studies and allow prompt and accurate diagnosis.

Adult↗

Sliding-screw plate fixation of proximal femoral fractures: radiographic assessment.

The sliding compression screw-sideplate combination is currently the most widely employed device for internal fixation of stable and unstable intertrochanteric fractures of the femur. The normal and abnormal radiographic appearances of this device in the immediate post-operative period are discussed. Potential long-term complications including mal- or non-union, intra-articular penetration, metal failure, rotation of the proximal fracture fragment, disengagement, trochanteric bursitis, leg length discrepancy, delayed cervical stress fracture, and ischemic necrosis are reviewed.

Bone Plates↗

Osteomyelitis and septic arthritis of the hand following human bites.

The spectrum of radiographic abnormalities accompanying bone and joint infection that results from human bites of the hand is presented in an analysis of 13 patients. Features include mono-articular involvement, predilection for a metacarpophalangeal joint, soft tissue swelling, joint space narrowing, bone erosions and periostitis. Magnification techniques may be required for early and accurate diagnosis.

Adult↗

Scapular foramina.

Although foramina in the scapula are a rare occurrence, they produce radiolucent defects that simulate those related to skeletal metastasis or multiple myeloma. In order to define the typical location and appearance of these foramina, we initiated a radiographic and pathologic examination of macerated modern and ancient scapulae. Of 93 macerated scapulae that were examined, foramina were observed in 27 specimens (29%). These occurred at four sites: at the superior border of the bone at its junction with the coracoid process, caused by ossification of the superior transverse ligament (21 specimens); in the body of the bone inferior to the scapular spine, resulting from a disturbance in ossification during fetal development (five specimens); in the superior fossa, as a clasp-like defect (one specimen); and, at the superomedial border above the scapular spine (one specimen). The radiographic features of these foramina were compared to those produced by normal vascular channels, anatomic thinning of the bone, and skeletal metastasis or multiple myeloma. Knowledge of the typical appearance and site of scapular foramina assures accurate diagnosis.

Humans↗

Myelofibrosis arising in treated histiocytosis X.

Myelofibrosis, or fibrous replacement of hematopoietic bone marrow, is rarely encountered in pediatric patients. An unusual, reversible case arising in the setting of treated histiocytosis X is reported, a previously undescribed association. The clinical, pathologic, radiographic, and scintigraphic characteristics of myelofibrosis are reviewed.

Antineoplastic Agents↗

The skeletal manifestations of clubbing: a study in patients with cyanotic congenital heart disease and hypertrophic osteoarthropathy.

The skeletal manifestations of clubbing of the digits have been occasionally noted and only briefly discussed in the literature. We investigated the radiographic features of digital clubbing in 37 patients with diverse diseases including cyanotic congenital heart disease, lung malignancy-associated hypertrophic osteoarthropathy, and idiopathic cases. We identified two types of bone changes--osteolysis or bone dissolution, and bone formation or hypertrophy. The changes were more evident in the feet than in the hands, and the degree of soft tissue change did not always reflect the underlying osseous abnormalities. The relationship of these changes (ie, osteolysis, hypertrophy) to each other appear to depend in part on the underlying disease as well as the time course or disease duration. Thus, clubbing and hypertrophic osteoarthropathy may not represent distinct entities; our data suggest that they may be stages in an evolving, more generalized process of new bone formation or hypertrophy followed by osteolysis or atrophy affecting many parts of the skeleton.

Adolescent↗

SLAC wrist.

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Adult↗

Plantar compartmental infection in the diabetic foot. The role of computed tomography.

This review discusses the role of computed tomography (CT) in the evaluation of extent of plantar soft tissue infection in the diabetic foot. CT abnormalities are correlated with conventional radiography, results of preoperative aspiration cultures, intraoperative assessment, and bone, gallium, and 111In-leukocyte scan findings. Plantar soft tissue disease respects compartmental boundaries in general, with transcompartmental spread possible along musculotendinous units that normally transgress the intervening fascial septae. CT correlates well with the extent of infection as determined by other modalities, but cannot precisely predict its proximal boundary due to gradual transition between unequivocally abnormal and normal tissue. CT may be useful in establishing an appropriate level for contemplated amputation and can detect extension of superficial diabetic foot infections at an earlier stage than existing clinical methods, potentially resulting in less extensive surgical procedures.

Bacterial Infections↗