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Biomedical subjects

D Reid

Publications and source records attributed to D Reid.

At least 145 records · Page 8Linked to original sources
PubMed1983

Susceptibility of itinerants ("travelling people") in Scotland to poliomyelitis.

A total of 109 travelling people (people with a nomadic lifestyle), living on 8 separate sites in central and south Scotland, were examined for neutralizing antibodies to poliovirus types 1, 2, and 3. Of those studied, 10% had no detectable antibody to poliovirus type 3 while 7% had no antibody to type 1, the types most commonly associated with outbreaks of paralytic poliomyelitis. Only one subject, a child aged 9 years, had no detectable poliomyelitis antibody; he had no history of poliomyelitis immunization. The best protected groups of travellers were those located on sites with good facilities.As far as poliomyelitis is concerned, we conclude that travelling people in Scotland who live on well equipped sites do not pose a hazard to nearby settled populations and, indeed, are no more vulnerable to infection than members of those communities.

Adolescent↗
PubMed1983

Circulatory support after coronary artery surgery.

An important change in the pattern of pharmacologic and mechanical circulatory support following coronary artery surgery has been noted in Newfoundland. The authors studied two groups of patients: group 1, 119 patients who underwent coronary artery bypass procedures from 1975 to 1978 and group 2, 344 similar patients studied from 1979 to 1982. Both groups of patients had similar left ventricular function and similar numbers of grafts per patient were inserted (group 1, 2.6; group 2, 2.8). There was a great reduction in the need for perioperative circulatory support (group 1, 34%; group 2, 6%), associated with a notable reduction in the rate of myocardial infarction perioperatively (group 1, 24%; group 2, 4.9%). This improvement resulted from the routine use of invasive hemodynamic monitoring and cold blood cardioplegia in group 2 patients.

Cardiopulmonary Bypass↗
PubMed1983

Travel and health: illness associated with winter package holidays.

A survey of 263 people who had winter package holidays abroad revealed that 21 per cent of the travellers had been ill. Forty-eight per cent of those who had been unwell reported an alimentary upset and 26 per cent reported respiratory symptoms. Illness was recorded most frequently by travellers to countries in the Mediterranean region.More readily available advice or information would be useful in reducing the amount of illness associated with package holidays.

Adolescent↗
PubMed1982

Glucose utilization and nitrogen balance in the obese on a protein-lipid hypocaloric diet.

Glucose utilization and insulin and growth hormone responses were evaluated in eight obese women by three rapid intravenous glucose tolerance tests (IVGTT): during a control period, and after 1 and 3 weeks of a 750 kcal/day protein-lipid diet (1 kcal = 4.1855 kJ). Weight loss averaged 454 g/day during the 1st week and 238 g/day for the 2nd and 3rd weeks of the diet. Nitrogen balance was maintained in equilibrium. Plasma insulin concentrations fell by 50% within 1 week of dieting; growth hormone levels were not modified. The net rate of glucose disappearance dropped from 0.98 to 0.65 and 0.68% min, the glucose pool from 16.2 to 13.3 and 13.4 g, and glucose utilization from 158 to 88 and 87 mg/min during the control period, and at 1 and 3 weeks of dieting, respectively. The insulinogenic index decreased from 0.41 to 0.24 to 0.16 with successive IVGTT's. The glucose volume of distribution was not modified with dieting. It is concluded that a hypocaloric protein-lipid diet induces (i) a carbohydrate intolerance not related to a negative nitrogen balance and (ii) a rapid initial weight loss which cannot be ascribed to a depletion of the glucose volume.

Adolescent↗
PubMed1981

Use of radiolabeled antibodies for localization of neoplasms. The state of the art.

The previous use of tumor-associated markers were to detect neoplasms early, before they had metastasized, and to monitor their treatment. Recently, antibodies to these tumor-associated markers have been radiolabeled, and the radiolabeled antibodies have been used to localize the neoplasms by external scintillation imaging. Potential now exists for treatment of the neoplasm by combining radiotherapeutic agents with the monoclonal antibodies to the neoplasm and infusing the patient with this combination. Three tumor-associated markers that are most often used are alpha-fetoprotein, carcinoembryonic antigen, and human chorionic gonadotropin beta-subunit. In addition, recently developed tumor-associated marker enzyme include galactosyl transferase isoenzyme II, creatine kinase BB, and radioimmunoassay of prostatic acid phosphatase isoenzyme.

Acid Phosphatase↗
PubMed1979

Legionnaires' disease and the traveller.

Respiratory illness occurred in members of a "package tour" to Benidorm, Spain, in 1973. Three of the tourists died with similar pneumonic illnesses, and 86 other travellers who had stayed at the same hotel also had respiratory illnesses. After the organism associated with the epidemic of Legionnaires' disease in Philadelphia 3 years later was identified, sera from patients involved with the "Benidorm episode" were tested. Evidence of infection with the Legionnaires' disease bacterium was obtained from sera from three of the patients who had died and from sera of two of the surviving tourists. Six of 16 members of the staff of the hotel involved had elevated titres to the LD bacterium, suggesting that there may be persistent or recurrent activity in a particular building or locality over a period of years. Surveys of travellers returning to Scotland have shown a large amount of illness, and studies are being conducted to determine the proportion caused by Legionnaires' disease.

Adult↗