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Biomedical subjects

D Owen

Publications and source records attributed to D Owen.

At least 127 records · Page 7Linked to original sources
PubMed1979

Eradication of the pinworm Syphacia obvelata from an animal unit by anthelmintic therapy.

Thiabendazole incorporated in the diet at a rate of 0.1%, fed to all animals over a period of 3 months, successfully eliminated the parasite from the colony. Samples taken 12 months after treatment were still negative for the parasite. During the period between the discovery of the organism and the preparation of the diet a course of piperazine citrate was administered at a rate of 2 g/litre in the drinking water in order to limit the spread of the infection.

Animals↗
PubMed1978

Pituitary-gonadal function in XYY and XXY men identified in a population survey.

Evidence on pituitary-gonadal function in XYY subjects has been inconclusive and based, for the most part, on selected samples such as institutionalized individuals or subjects examined for particular behavioural or medical characteristics. We report the results of a double-blind hormonal study of a sample from an entire well-defined birth cohort of men. The starting population included all males born in Copenhagen during the period 1944-1947 comprising 31,436 individuals. Chromosome determinations conducted on 4139 men representing the top 15.9% of the height distribution of the sample identified 12 XYY and 16 XXY men. All the XYY subjects and 14 XXYs consented to participate in an individual case study and were individually matched to XY controls selected from the total sample. The XYY men had significantly higher plasma concentrations of LH, FSH and testosterone than matched XY controls. There were no differences in testicular size and in the reported number of children between the XYYs and control group. XXY men from the same population showed significantly higher LH and FSH, lower concentrations of testosterone, had smaller testes and reported fewer children than their matched controls.

Adult↗
PubMed1978

Attempted transmission of Entamoeba coli to specified-pathogen-free rodents.

An attempt was made to establish whether human Entamoeba coli was transmissible from man to laboratory rodents. Cysts from 15 samples of human and 4 of primate stool were passaged into specified-pathogen free guinea-pigs, rats and mice. In only 1 instance were cysts established in mice and, eventually, in rats.

Amebiasis↗
PubMed1978

Effects of pelleting and sterilization of diet on 2 strains of rabbit coccidia.

Both autoclaving and irradiation at levels currently used for other laboratory animal diets appear to be satisfactory for the elimination of 2 of the most robust and pathogenic species of rabbit coccidia. Pelleting by the usual methods, even at 68 degrees C, was found to be unsatisfactory in eliminating all oocysts from heavily infected diet.

Animal Feed↗
PubMed1978

Prolonged, transapical left ventricular bypass (TALVB) in sheep and man.

Transapical left ventricular bypass has been demonstrated in normal sheep and one lamb. Recently, TALVB was applied in 3 clinical cases of cardiac failure, with recovery of myocardial function in one patient after 9 days of bypass (6 days total TALVB). These studies suggest that LV apical cannula-roller pump bypass with low dose heparin anticoagulation and secondary surgery to remove the cannula may salvage some patients now dying of temporary cardiac failure.

Adult↗
PubMed1977

Observations of dye test (DT) titres to Toxoplasma in a non-breeding flock of sheep.

In this study nine sheep and one goat were tested by the Sabin Feldman dye test for the presence of antibodies to Toxoplasma spp over a period of 12 months. No significant signs of a seasonal variation in dye test titres of infected animals could be demonstrated. The possible source of infection of two sheep, exhibiting a sudden rise in antibody titre during the course of the observations is discussed.

Animals↗
PubMed1977

A binocular perimeter.

A newly designed visual field testing instrument may be used either binocularly, as a quick screening test, or uniocularly, for plotting field defects. During binocular testing, the patient views a single target light at various points in the binocular central field. The eyepieces through which the patient looks and which contain weak prisms induce an artificial diplopia, and the patient sees two target lights. If the patient responds that he sees only one, then a field defect is present in one eye. Further analysis of the fields is then tested uniocularly. The instrument is simply constructed, yet should provide the means for assessing visual fields quickly and accurately.

Humans↗
PubMed1976

The frequency of chromosome aberrations in tall men with special reference to 47, XYY and 47, XXY.

All men born during the years 1944-1947 to mothers who were inhabitants of Copenhagen when they gave birth, were identified. The adult heights of all but 2,552 of these 31,438 men were obtained; a group of 4,591 men at least 184 cm tall were selected for examination. Samples for chromosome studies were obtained from 4,139 (90.2%) of these tall men. A total of 41 (1%) abnormalities were identified (33 sex chromosome abnormalities, including 12 XYYs (0.3%) and 16 XXYs (0.4%), 6 autosomal abnormalities, and two of uncertain origin). The XYY and XXY groups were taller than the selected sample of tall XY men.

Adult↗
PubMed1975

Owen on Briggs.

Explore the source record for details and available documents.

Economics↗