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Biomedical subjects

D Nolte

Publications and source records attributed to D Nolte.

At least 163 records · Page 9Linked to original sources

[Phospholipase D - a review (author's transl)].

Phospholipase D (phosphatidylcholine-phosphatidohydrolase, EC 3.1.4.4) hydrolyses lecithin into phosphatidic acid and choline. A review is given on the properties of phospholipase D described in the literature; it deals with the occurrence and distribution of phospholipase D in higher plants, with it's pH and temperature, substrate specifity, activators, inhibitors and with occurrence and properties of bacterial phospholipase D.

Choline↗

[Acupuncture - has it a demonstrable bronchospasmolytic effect in bronchial asthma (author's transl)].

In 12 patients with bronchial asthma the effects of acupuncture (45 tests altogether) on airway resistance have been investigated. In 9 patients there was a significant decrease of airway resistance 10 minutes, 1 hour and 2 hours after the end of acupuncture. The lowest level for airway resistance (70,1% of control value) was reached during the first hour after acupuncture. The possibility of a merely suggestive effect could be excluded, because "placebo-acupunctures" did not change airway resistance significantly. The comparison with a parasympatholytic acting drug as a metered aerosol (Atrovent) demonstrated that acupuncture had a some-what weaker bronchospasmolytic effect. 3 patients showed after repeated acupunctures no reaction whatever.

Acupuncture Therapy↗

[Phospholipase D of cereals (author's transl)].

Phospholipase D containing water insoluble fraction was isolated from mature barley; the enzym preparation only had weak phospholipase B activity. The phospholipase D of barley was activated by Ca2+, diethyl ether and sodium dodecyl sulphate (SDS); EDTA inhibited the enzyme to an extent of 10% of the original activity. Diethyl ether and SDS showed and additive effect. Phospholipase D activated by CaC12, diethyl ether and SDS exhibited a sharp optimum at pH 6.6. Lysophosphatidylcholine was hydrolysed much slower than phosphatidylcholine. Diethyl ether and SDS also increased the breakdown of the lysophosphatidylcholine.

Edible Grain↗