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Biomedical subjects

D M Wilson

Publications and source records attributed to D M Wilson.

At least 325 records · Page 18Linked to original sources

Nonheuristic computer determination of molecular structure based upon carbon-13 nuclear magnetic resonance data: branched alkanes.

A computer-based system for elucidation of molecular structure is described for the branched alkanes, based upon (13)C nuclear magnetic resonance data. All possible structures of a given carbon content are exhaustively generated in a DENDRAL-like manner, and scored according to the fit of their predicted spectral characteristics to those of the "unknown" alkane. The technique may be generalized to any class of organic compounds for which (13)C chemical-shift additivity parameters are reliable, and shows promise for stereochemical elucidation.

Alkanes↗

Patulin production in apples decayed by Penicillium expansum.

Sixty isolates of Penicillium expansum were tested for patulin production in decaying apples. All the isolates were found to produce the mycotoxin patulin as determined by thin-layer chromatography. Since patulin is known to be stable in many apple products, the results indicate that apple products made partially from apples decayed by P. expansum will contain patulin which may present a health hazard. The results also suggest that patulin may be important in the decay of apples by P. expansum.

Chromatography, Thin Layer↗