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Biomedical subjects

D M Albert

Publications and source records attributed to D M Albert.

At least 451 records · Page 25Linked to original sources
PubMed1975

Oxalate retinopathy: an experimental model of a flecked retina.

The clinical picture resembling fundus albipunctatus was seen to develop in rabbits following subcutaneous injection with dibutyl oxalate. On histologic examination, the flecks were found to be due to intracellular accumulation of calcium oxalate in the RPE cells. The clinical and histologic features of this animal model closely resemble the recently described entity of oxalate retinopathy in humans which was seen in the presence of high circulating oxalate levels. It is suggested that the presence of metabolic disorders or toxicity which are known to cause oxalate depositions should be sought in patients with fundus albipunctatus.

Animals↗
PubMed1975

Ultrastructural description of a "cylinder organelle" in the outer plexiform layer of human retinas.

A cylinder-like organelle ("cylinder organelle") present in the outer plexiform layer of the retina and apparently confined to the horizontal cell processess is described. This structure was studied in detail in three normal human retinas from eyes enucleated for ciliary body melanomas. The cylinder organelle, when cut longitudinally, showed an electron-lucent area bound by two bands of electron-dense filaments. In transverse section, the cylinder organelle revealed a circular profile of electron-dense crisscrossing filaments about an electron-lucent matrix. Since this structure was only found in the rod spherule synaptic complex, it is hypothesized that it may be involved in transmitting impulses.

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