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Biomedical subjects

D Lubach

Publications and source records attributed to D Lubach.

At least 55 records · Page 3Linked to original sources

[Skin changes in hemodialysis patients].

188 patients undergoing long-term hemodialysis and a control group of 371 patients without kidney diseases were examined with regard to changes of the connective tissue of the skin. The following alterations were observed: increased sensibility to low temperatures and Raynaud's syndrome (42%), Dupuytren's contracture (22.4%), sclerosis of the dorsum of the fingers (17.6%). Carpal tunnel syndrome was seen in 24.4% of the cases, significantly correlating with the duration of hemodialysis.

Female↗

[Pityriasis versicolor pseudoatrophicans. A case description].

We report on a pseudoatrophic manifestation of tinea versicolor. A 32-year-old female patient, who had suffered from typical spotty lesions of tinea versicolor for 12 years, now additionally developed pseudoatrophic lesions within a few weeks. Complete remission of these lesions after local antimycotic therapy as well as mycological and histopathological findings confirmed the diagnosis of pseudoatrophic tinea versicolor.

Adult↗

New techniques of demonstrating lymph vessels in skin biopsy specimens and intact skin with the scanning electron microscope.

Two new methods now allow the systematic examination of the morphology and micropathology of the initial lymphatics (lymph sinuses and precollectors) in human skin biopsy specimens under the scanning electron microscope. Pertinent studies and findings in the intact skin of anesthetized pigs demonstrate the standard quality of the biopsy preparations. The following are new findings made with these methods: in the skin of the human head, both the lymph sinuses and the precollectors extend as far as the epidermis. The opening apparatus of these vessels consists not only of anchoring filaments and interendothelial openings, but also of endothelial bridges and trabeculae. The interendothelial openings can be present in three types of transformation (Type I-III). As part of these studies, an attempt was made to standardize the lymphological nomenclature so that it would be acceptable to both anatomists and clinicians.

Adult↗

Skin tags: localization and frequencies according to sex and age.

The relevant literature does not contain detailed numerical data about skin tags. We found 46% skin tag carriers in 750 unselected persons (25% males and 21% females). The risk of getting skin tags increases with age. The age of 50, however, seems to be a turning point, at which a stagnation of the increase is observed. The majority of the carriers had no more than 3 tags per localization; the most frequent localization was the axilla, followed by the neck. This study supplies objective data for the evaluation of skin tags as markers for colonic polyps and may provide standard values for future studies.

Adolescent↗

Scanning electron microscopy of the initial lymphatics of the skin after use of the indirect application technique with glutaraldehyde and MERCOX as compared to clinical findings.

Certain phenomena in the region of the initial lymphatics during clinical examination (indirect lymphography and microlymphography)--namely build-up and course and filling and diffusion--have still to be elucidated. The glutaraldehyde and MERCOX methods were used to simulate indirect application conditions in clinical procedures in skin specimens (human and pig) which were then examined by scanning electron microscopy. The results presented include novel findings on the microtopography of these lymph vessels and the typology of filling refluxes which are of importance when indirect imaging techniques are employed. Various speeds of application were used and the function of the opening apparatus with previously undescribed structures (endothelial bridges and connective tissue trabeculae) was taken into consideration. Recommendations aimed at standardizing the nomenclature of parietal structures and sections of the lymphatics have been incorporated in the report.

Aldehydes↗

[Changes in the oral mucosa in psoriasis pustulosa generalisata].

A case of 7-year-old female patient with generalized pustular psoriasis associated with geographical tongu is described. Antipsoriatic therapy with etretinate caused a remarkable regression in the tongue lesions. In accordance with previous case reports, observations suggest that geographic tongue can after be a typical symptom of psoriasis pustulosa generalisata.

Biopsy↗

Incidence of brittle nails.

Only few reports exist about the occurrence of brittle nails. We examined 1,584 persons with respect to the incidence of this anomaly. The patients were from five different groups: outpatients of a dental clinic, blood donors, residents of an old people's home, patients of a clinic for internal diseases and patients of a general practice. Approximately 20% of the subjects examined had brittle nails. Women suffered from brittleness of nails much more frequently than men (27 vs. 13%) with a ratio of men to women from 1:1.6 to 1:7 depending on age. 44% of the subjects affected (75% of the females, 25% of the males) had tried one or several treatments but only 26% believed in their curative effect. The market for the therapy of brittle nails in the FRG is estimated to be between 2 and 4 million people.

Adolescent↗

[A pseudolymphomatous reaction in tattooing].

A pathological reaction developed in the red area of a professionally executed tattoo. The reaction appeared 12 years after tattooing. Histological examination of a biopsy specimen revealed a lymphoplasia.

Adult↗

[Superficial purpura with necrosis in severe consumptive coagulopathy. Clinical study].

In this report the case history of three patients with superficial, non-inflammatory purpura is described. In all patients the purpura demonstrated partially reticular, partially racemose configuration. Signs of disseminated intravascular coagulation were detected in two patients. One patient developed disseminated intravascular coagulation caused by an overwhelming postsplenectomy infection. Nosological position, pathogenesis and differential diagnosis of this kind of purpura are discussed.

Adolescent↗

Gingival manifestation in linear nevus sebaceous syndrome.

Gingival involvement was observed in an 11-year-old female patient with linear nevus sebaceous syndrome. Clinical, histological and scanning-electronmicroscopic findings are described. 4 years after surgical removal, the oral lesion recurred; clinical and histological features are presented. Problems in diagnosis, differential diagnosis and validity of oral involvement in the linear nevus sebaceous syndrome are discussed.

Child↗