Monoamine oxidase in man: enzyme characteristics in platelets, plasma, and other human tissues.
Explore the source record for details and available documents.
Age Factors↗
Biomedical subjects
D L Murphy
Publications and source records attributed to D L Murphy.
Reduced monoamine oxidase activity in platelets: a possible genetic marker for vulnerability to schizophrenia.
Monoamine oxidase activity in blood platelets was measured, with [(14)C]tryptamine as substrate, in 13 monozygotic twin pairs discordant for schizophrenia and in 23 normal volunteers. The monoamine oxidase activity of both schizophrenic and nonschizophrenic co-twins was significantly lower than it was for the normals, and it was highly correlated between twins. In addition, there was a significant inverse correlation between a measure of the degree of the schizophrenic disorder and the monoamine oxidase activity. These data suggest, but do not prove, that reduced platelet monoamine oxidase activity may provide a genetic marker for vulnerability to schizophrenia.
Adult↗
Serotonin and platelet function in Duchenne muscular dystrophy.
Explore the source record for details and available documents.
Blood Platelets↗
Primary affective disorder: MMPI differences between unipolar and bipolar depressed subjects.
Explore the source record for details and available documents.
Adult↗
Social desirability and bipolar affective disorder.
Explore the source record for details and available documents.
Bipolar Disorder↗
Mental effects of L-dopa.
Explore the source record for details and available documents.
Affective Symptoms↗
Serotonin and central nervous system function.
Explore the source record for details and available documents.
Affective Symptoms↗
L-dopa, dopamine, and hypomania.
Explore the source record for details and available documents.
Adult↗
Influence of affective states and psychoactive drugs on verbal learning and memory.
Explore the source record for details and available documents.
Bipolar Disorder↗
Primary affective disorder: delineation of a unipolar depressive subtype.
Explore the source record for details and available documents.
Affective Symptoms↗
Reduced monoamine oxidase activity in blood platelets from schizophrenic patients.
Explore the source record for details and available documents.
Adult↗
Catecholamines and indoleamines in patients with Duchenne muscular dystrophy.
Explore the source record for details and available documents.
Adolescent↗
Excretion of 17-OHCS in unipolar and bipolar depressed patients.
Explore the source record for details and available documents.
17-Hydroxycorticosteroids↗
The "switch process" in manic-depressive illness. I. A systematic study of sequential behavioral changes.
Explore the source record for details and available documents.
Affect↗
The "switch process" in manic-depressive illness. II. Relationship to catecholamines, REM sleep, and drugs.
Explore the source record for details and available documents.
Affective Symptoms↗
The "switch process" in manic-depressive illness. 3. Theoretical implications.
Explore the source record for details and available documents.
Biological Transport, Active↗
Comparison of temporal lobe epileptics and affective disorders on the Halstead-Reitan test battery.
Explore the source record for details and available documents.
Adult↗
Catecholamines and memory: enhanced verbal learning during L-DOPA administration.
Explore the source record for details and available documents.
Administration, Oral↗