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Biomedical subjects

D Krebs

Publications and source records attributed to D Krebs.

At least 235 records · Page 13Linked to original sources
PubMed1978

[Measurement of fluorescent polarisation in the amniotic fluid to assess fetal lung maturity (author's transl)].

A new method for determining fetal lung maturity is discussed. Molecular mobility can be determined spectrophotometrically by measuring the fluorescent polarisation (FP) in lipid solutions. This method of determining the microviscosity in lipid solutions can now be applied also in the amniotic fluid. Measurement of FP by means of an electro-optical microviscosimeter is proportional to the lipid concentration in the amniotic fluid and is in good correlation with fetal lung maturity. FP was measured between the 17th and 41st weeks of gestation in 147 amniotic fluid samples. During pregnancy the FP value drops significantly from 0.350 to 0.200. A FP value of 0.290 was fixed as the limit value beyond which RDS may be expected to occur. With a limit value of 0.290, the RDS identification probability was calculated at 94%, whereas the calculated probability of RDS was 81% and the exclusion probability of RDS 97%. At the same time, the probabilities, calculated on the parallel determination of the L/S ratio, yielded a slightly more unfavourable result. The drop in the FP level correlates significantly with the increase of the L/S ratio in the investigated amniotic fluid samples (correlation coefficient 0.77). The method, which requires very special equipment, offers many advantages: it is very accurate, simple, well reproducible and can be performed within half an hour at relatively low laboratory cost.

Amniotic Fluid↗
PubMed1976

Blastoid transformation of lymphocytes in response to spermatozoa.

Microlymphocyte transformation tests were done on 33 female rabbits immunized with different components of rabbit ejaculate. In rabbits injected with total ejaculate or washed spermatozoa a specific stimulation of lymphocytes could be demonstrated by exposure to washed spermatozoa. It is shown that it is necessary to notice the length of time for cultivation, the antigen concentration and especially the time-interval after the last immunization.

Animals↗
PubMed1975

Empathy and altruism.

The psychophysiological responses of 60 subjects were measured as they observed a performer play a roulette game. Half of the subjects were led to believe that they were similar to the performer in personality and values, and half were led to believe that they were dissimilar. Half of the subjects in each condition believed that the performer won money and experienced pain as he played the game, and half believed that he performed a cognitive and motor skill task. Subjects who observed a performer who ostensibly experienced pleasure and pain exhibited greater psychophysiological reactions than subjects who did not. Subjects who believed they were similar to the performer tended to react more strongly than subjects who believed they were different from him. Similar subjects also reported identifying most with the performer and feeling the worst while he waited to receive shocks. It was concluded that the similar subjects empathized most with the performer who appeared to experience pleasure and pain. When required to make a choice between helping themselves at a cost to the performer or helping the performer at a cost to themselves, the subjects who reacted most empathically behaved most altruistically. The results were interpreted as casting some light on century-old questions about the human capacity for altruism.

Adult↗
PubMed1975

Physical attractiveness, social relations, and personality style.

The relationship between physical attractiveness, social contact with members of the same and opposite sex, and personality factors was determined. Sixty male and 60 female university freshmen who were rejected, accepted, or unknown to their same-sex peers served as subjects. A reliable rating of physical attractiveness by independent judges showed that rejected subjects were most attractive, accepted subjects were next most attractive and unknown subjects were least attractive. There was a positive relationship between physical attractiveness and dating for females, but not for males. A factor analysis of subjects' personality inventory scores and subsequent analyses of variance of personality factors by sociometric groups showed that rejected subjects of both sexes were independent, achieving, and ambitious; accepted subjects were affiliative and affectionate; and isolated subjects were emotionally constricted, defensive, and withdrawn.

Achievement↗