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Biomedical subjects

D Krebs

Publications and source records attributed to D Krebs.

At least 217 records · Page 12Linked to original sources

Role-taking, moral development, and mental retardation.

Role-taking ability and level of moral development were measured in three groups of boys and girls including 16 moderately retarded adolescents (mean chronological age 15; mean mental age 9), 16 nonretarded adolescents matched for chronological age, and 16 nonretarded children matched for mental age. The mentally retarded adolescents scored significantly lower on role-taking ability and moral development than the adolescents matched for chronological age. They did not differ from children of their same mental age in role-taking ability; and they tended to score lower in moral development. The results supplied qualified support for Kohlberg's theory of moral development.

Adolescent↗

Beta-[1-Phenyl-5-bis(beta-chloroethyl)-amino-benzimidazolyl-(2)]-DL-alanine (ZIMET 3164): an immunosuppressant without marked anti-cancer effect.

ZIMET 3164 inhibited the growth of sarcoma 180 P, sarcoma 180 G, and Walker 256 carcinosarcoma, but was unable to prolong the survival time of mice bearing Ehrlich ascites carcinoma or the leukaemias L 1210 and LAJ I to a worthwhile extent. The primary and secondarantly suppressed in mice. The drug exerted maximum effect when given on days--2 to +2 relative to antigenic stimulus. Administration exclusively prior to immunization induced only moderate immunosuppression while injection afterwards failed to affect the primary response at all, suggesting that the drug interfers with the afferent limb of immune response. In general, ZIMET 3164 proved to be half as effective as cyclophosphamide, but more effective than chlorambucil.

Animals↗

[Caudal anaesthesia in obstetrics (author's transl)].

The advantages of caudal anaesthesia in obstetrics far outweigh the few disadvantages. The perinatal mortality of premature infants is reduced under caudal anaesthesia. Breech deliveries are easier under caudal anaesthesia. In these cases regional anaesthesia is considered an obstetrical indication. It is possible to carry out all vaginal and abdominal procedures with this anaesthesia. The elimination of pain during labor and delivery permits a more intensive experience of labor and delivery for the mother under caudal anaesthesia.

Anesthesia, Caudal↗

Studies on the methodology and evaluation of the lymphocyte transformation microtest.

Optimum experimental conditions for the lymphocyte transformation microtest in healthy persons are described. The dependence of PHA stimulation on duration of culture, additions of serum and PHA concentration is investigated. A function of normal distribution pattern can be set up by determining the lymphocyte stimulability with four different PHA concentrations in the optimal stimulation range. With this function, the area under the curve, steepness, position and height of the maximum can be calculated. These parameters should serve for better interpretation of cellular immunity.

Adult↗