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Biomedical subjects

D Krause

Publications and source records attributed to D Krause.

At least 181 records · Page 10Linked to original sources
PubMed1981

[Atheromatous coronary artery disease: value of a study of calcification during assessment (author's transl)].

Correlations between calcifications and stenoses observed on coronarography were studied in 200 patients with coronary heart disease and calcifications in the coronary arteries. There was a very close relationship (p less than 0.0005) between the number of calcified and stenosed main coronary vessels. Calcification in the circumflex and right coronary vessels is a specific sign of stenosis. There was a high frequency of poor arterial beds distal to the stenoses when these were calcified. It is considered that the detection of coronary calcification by means of a brilliance amplifier constitutes one of the most effective non-invasive methods for assessing coronary artery disease.

Adult↗
PubMed1980

New development in surgical andrology. Alloplastic spermatocele.

We developed a cup-shaped silicone-dacron prosthesis that may be used as a sperm reservoir. Spermatozoa aspirated from this reservoir and stored as pellets in liquid nitrogen for 6 weeks induced pregnancies and normal births in 50 per cent of inseminated cows. Because of aplasia or long stenosis of the vas deferens 26 prostheses were implanted upon the epididymis in 14 patients. Percutaneous aspirations up to 7 months postsurgery showed 0.3 to 105 million spermatozoa the quality and quantity of which decreased with time. Insemination of patients' wives has not resulted in pregnancy.

Animals↗
PubMed1978

[Active therapeutic exercises in combination with vasoactive drug in intermittent claudication (author's transl)].

Earlier investigations have shown that the success of physiotherapeutic exercises in peripheral arterial circulatory disturbances in stage II (Fontaine) can be increased by additional administration of "vasoactive" substances. In the present double-blind study, therefore, 102 outpatients were treated with magnesium nicotinate-magnesium dehydrocholate or a placebo in addition to basic physical therapy. The drug collective (n = 50) showed an increase in walking distance of 24.1% compared with the placebo group (n = 52). Also, in respect to the success rate, the drug collective did better, which, however, may have been due to the unequal distribution of the prognosis factors. Yet it may be concluded that the physiotherapeutic exercises can be effectively supported by the drug tested.

Aged↗
PubMed1978

[Estimation of pharmacokinetic constants in irregular repeated drug administration (author's transl)].

Least squares estimations for the fraction of the dose absorbed, volume of distribution, absorption and elimination rate based on drug measurements in blood and urine after aperiodical administration are described for a one-compartment model with first-order absorption. The non-linear regression analysis is carried out by means of a modified Gauss-Newton iteration procedure by Hartley. BASIC and FORTRAN functions are developed and applied in an example. The advantages of unbiased and consistent least-squares estimations in pharmacokinetics are pointed out.

Kinetics↗
PubMed1977

[Important prognostic factors for the results of physiotherapeutic exercises in intermittent claudication (author's transl)].

In 240 patients with peripheral circulatory disorders (Fontaine Stage II) who had participated in intensive physiotherapeutic interval training daily for 6 weeks between October 1974 and July 1976, it was established that the therapeutic results were not related to age or sex. The "risk" factors of smoking, diabetes mellitus, hypertriglyceridemia, hypercholesterolemia and hyperuricemia individually show no connection with the results. Only overweight, hypertension and coronary heart disease appear to have an unfavorable influence. It is distinctly recognizable that the more risk factors there are combined in a patient with intermittent claudication, the less chance he has of success in physiotherapeutic vessel training.

Aged↗
PubMed1977

[Success of physiotherapeutic interval training combined with standardized hemoderivative in intermittent claudication (author's transl)].

In a cross-over trial with 114 patients, intravenous Actovegin or an oral placebo were administered in addition to basic physiotherapy. In the evaluation 105 of the subjects were taken into consideration. It was shown that the test group (n = 53) achieved a 12% increase in walking distance (measured in the standardized walking distance test) compared with the placebo group (n = 52). The therapeutic success rate, i.e. the evaluation base for the efficacy of basic physiotherapy was comparatively good and statistically confirmed at 69.8% and 73.1% for the two groups. From this it may be concluded that basic physiotherapy can be effectively supported by Actovegin.

Actihaemyl↗
PubMed1977

Some ultrastructural and functional aspects of the golgi àpparatus of Thelohania sp. (Microsporida) in the shrimp Pandalus jordani Rathbun.

Electron microscope observations on Thelohania sp. in the shrimp Pandalus jordani support the view that the Golgi complex in Microsporida is a "classical" one, composed of vesicular, vacuolar, and cisternal components. During development of the sporoblast, a portion of the Golgi complex is seen as an electron-dense reticulum enmeshing the core of the polar filament. Associated with the reticulum are electron-dense bodies. The reticulum and "dense bodies," reported in several previous publications, have not been well understood and have been given a variety of names. The evidence favors the view that these structures have secretory activity in which the reticulum concentrates or synthesized material, some of which takes the form of membrane-bounded granules. It is suggested that the most appropriate name for the reticulum is "reticulum golgien," and the the correct name for the "dense bodies" is the standard cytologic term, "secretion granules." The secretion granules apparently remain in the posterior part of the spore, and may be stored there for some as yet undetermined use.

Animals↗
PubMed1977

[The alcohol effect on the latency time of acoustically evoked potentials (author's transl)].

The alcohol effect on the latency time of acoustically evoked potentials (ERA and 7 ms-Potentials) was investigated in 19 normal hearing persons. The latency time for N1 of the slow evoked potentials was significantly longer by alcohol concentrations of more than 1%. By blood levels=1.5% and by low stimulus intensity the results were more distinct. The alcohol effect was not registered by the brainstem potentials.

Acoustic Stimulation↗
PubMed1977

[Big particle biopsy. An aid in the differential diagnosis of gastric lymphomas (author's transl)].

A definite clinical, radiological, endoscopic or bioptic diagnosis of gastric lymphosarcoma cannot usually be achieved. An attempt to establish the diagnosis should be made, firstly, because of the better prognosis compared to gastric carcinoma, and secondly, because of the alternative therapy available. In the case described the correct diagnosis could be established only by the big particle technique, but not by the conventional forceps biopsy method. The procedure is easy to be done and almost free of complications and is to be recommended whenever an endoscopic suspicion of gastric lymphosarcoma exists.

Aged↗
PubMed1976

[Combination of physiotherapeutic exercise therapy with bencyclane in intermittent claudication (author's transl)].

Earlier investigations had shown that an intensive physiotherapy program with 30 treatments in 6 weeks was the most rational therapy for intermittent claudication, but the question whether the therapeutic success could be improved by the addition of "vasoactive" substances remained open. For this reason, bencyclane was added to the basic physiotherapy in a double blind trial involving 109 ambulant patients. 91 or these were evaluated. The treatment group (n = 45) showed a greater increase in walking distance of 21.7% compared with the placebo group (n = 46). Also in the evaluation of the therapeutic success rate, the treatment group showed better results (84.4%) than the placebo group (71.7%). From this it can be concluded that the basic physiotherapy can be effectively supported with bencyclane.

Adult↗
PubMed1976

[Sympatholytics].

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Adrenergic alpha-Agonists↗