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Biomedical subjects

D Koischwitz

Publications and source records attributed to D Koischwitz.

At least 55 records · Page 3Linked to original sources

[Sonographic morphology of primary and secondary tumours of the liver (author's transl)].

The sonographic morphology of benign and malignant primary and secondary tumours of the liver has been studied in 153 patients who had been investigated histologically. Eight sonographic appearances have been distinguished: Circumscribed tumours, which may be echo-free, with a faint echo, a homogenous strong echo, strong central echo with faint marginal echo, faint echo with strong marginal echo, strong with acoustic shadowing or a combination of various types; there may be diffuse tumour infiltration. Some correlation between sonographic patterns and tumour type can be recognised. However, unequivocal agreement between sonographic appearances and histological findings has not been established. Nevertheless, the various sonographic appearances of intrahepatic tumours provide valuable information concerning tumour architecture; in conjunction with clinical information this makes a diagnosis possible in a proportion of cases.

Adolescent↗

Lung function studies in a patient with diffuse pulmonary fibroleiomyomas.

Diffuse pulmonary fibroleiomyomas were detected by open-lung biopsy in a 33-year-old male patient. Lung function studies revealed severe airflow obstruction, hyperinflation, grossly impaired single-breath-diffusing capacity and a decrease in PaO2 during exercise, i.e. data which are compatible with pulmonary emphysema. However, static lung compliance was within normal limits excluding the existence of pure emphysema. Additional special lung function tests confirmed the assumption that in diffuse fibroleiomyomas of the lung, functional patterns characteristic of obstructive and restrictive lung disease are present that are in agreement with the histological features of this disease.

Adult↗

[Fibrinolytic treatment with urokinase in older phlebothrombosis (author's transl)].

28 patients with 1 to 6 week old occlusions of the femoral and/or iliac veins as well as the subclavian veins were treated with a standardised urokinase-heparin-scheme. The fibrinolytic therapy was generally performed over a period of 7 to 14 days. In 2 patients, the 1 and 6 weeks respectively old thromboses of the iliac, femoral and tibial veins, and in 4 patients the 5 to 16 days old thromboses of the subclavian veins could be dissolved completely, 16 patients showed clinically and phlebographically a substantial amelioration. In 6 patients no marked success was found.

Adult↗

[The diagnosis of hydatid disease of the liver by ultrasound (author's transl)].

Demonstration and localisation of hydatid disease in the liver by ultrasound was successful in 41 patients (35 with cystic and 6 with alveolar disease). In cystic hydatid disease the demonstration of a cyst which contains a daughter cyst (5 of 35 cases), as well as a cystic conglomerate enclosed in a smooth capsule (17 of 35 cases), is typical for the disease. In 22 patients ultrasound alone provided the correct diagnosis. In the alveolar form the ultrasound findings were not typical for the parasite and could not be differentiated from solid or necrotising malignant tumour of the liver. The ultrasound method is thus of great value in the diagnosis of cystic hydatid disease, but if the findings are unclear--especially if the alveolar type of disease is suspected--further studies of the disease, in particular angiography, must be undertaken.

Angiography↗

[Sonographic determination of liver volume. Problems, methods and practical significance of liver volume measurements (author's transl)].

A sonographic procedure is described which permits accurate determination of liver volume by simple means. Comparison between the sonographic measurements and volume determinations at autopsy carried out by water displacement of the isolated organ showed a statistical error of +/- 1.58% and for average liver volumes of 1,800 ml and 95% limits of confidence of -84 to +20 ml. Quantitation of liver size may be an important clinical measurement, e.g. in assessing the possibility of shunts in the lieno-portal system in portal hypertension with recurrent bleeding from oesophageal varices due to cirrhosis of the liver, for evaluating liver atrophy after shunts affecting the liver, for demonstrating liver size in right heart insufficiency and congestive states or for the control of the effectiveness of cytostatic drugs in lymphatic or haematological disease.

Autopsy↗

[Diagnostic value of sonography of the bile ducts (author's transl)].

In obstructive biliary disease sonography proves to have a high diagnostic informative value. Dilatation of intra-and extrahepatic bile ducts is documented sonographically. In the majority of cases, analysis of sonographic findings will clarify the cause of biliary obstruction like cholecysto-cholangiolithiasis, carcinoma of the head of the pancreas, or various neoplastic disease in the area of the liver hilus. The obtained information is independent from contraindications like contrast medium allergies and severe parenchymal liver disease with impaired biliary secretion of contrast media.

Bile Duct Diseases↗

[Duodenal stenosis in chronic relapsing pancreatitis (author's transl)].

Duodenal stenosis in chronic relapsing pancreatitis occurs in 20% of our patients. In 21 of our cases, the stenosis was always in the descending portion of the duodenum, and in two-thirds it caused an obstruction. The stenosis is always concentric with destruction of the mucosal pattern, widening of the neighbouring folds, irregular contours, and, possibly, straightening of the medial margin of the duodenum. There may be widening of the duodenal loop and frequently the duodenal loop is dilated. The causes for these appearances vary, but a peri-pancreatitis or duodenitis are most frequent. There is no close relationship with the severity of the pancreatitis. Our findings are compared with the small number of reports to be found in the literature.

Adult↗

[Comparison between computer tomography and ultrasound in abdominal and renal growing and displacing processes (author's transl)].

The advantages and limitations of both methods are analyzed and compared. The comparison is effected on the basis of the present standard of equipment. The results obtained with both methods are demonstrated by means of the example of frequent epigastric diseases. Despite the still limited number of patients examined simultaneously both by ultrasound and computer tomography, it seems that the sensitivity of both methods in case of growing and displacing processes in the epigastric or renal regions, does not differ greatly. A comparison of the specificity of both methods will be effected only after a large number of patients has been examined by both methods at the same time.

Abdominal Neoplasms↗

Radiographical and endoscopical studies on two cases of intraluminal diverticulum of the duodenum.

Case report of two intraluminal diverticula of the duodenum. It is a rare congenital lesion characterized by a double layered mucosal sac lying in the duodenal lumen near the ampulla of Vater. Clinical features and laboratory findings are uncharacteristic. X-ray examination is the diagnostic method of choice, endoscopy will give further information about inflammation, haemorrhage and localisation of the ampulla. Treatment of choice is either surgical excision or endoscopical splitting of the diverticulum.

Adult↗

[The accuracy of sonography in the diagnosis of renal disease (author's transl)].

The accuracy of sonography in the diagnosis of spaceoccupying renal lesions was evaluated by a retrospective study of 221 patients. There were 15 incorrect diagnoses. In 93% of cases the sonographic diagnosis was correct. Erroneous diagnoses, which would have been difficult to avoid even retrospectively, were usually due to complex lesions which were partly cystic and partly solid. In order to differentiate cysts from solid lesions it is considered essential to use both A- and B-scans and step-wise variations of sound energy. These results emphasise the great value of ultrasound in the differentiation of renal abnormalities. Sonography should be used, during the clinical work up, after the urogram, but before angiography or other invasive methods are employed.

Adult↗