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Biomedical subjects

D Jones

Publications and source records attributed to D Jones.

At least 937 records · Page 52Linked to original sources
PubMedDate not supplied

Ten years experience with a conservative approach to radial keratotomy.

This retrospective study reports the results of radial keratotomy surgery on 225 eyes of 135 patients by one surgeon. Fifty-one percent of the eyes had four incisions and 45% had eight as the initial procedure. Fifteen percent of the eyes repeated surgery. The mean preoperative spherical equivalent refraction was -5.10 diopters (SD 1.90, range 1.20 to 11.60 D) and at 3 months to 1 year, the mean was -0.60 D (SD 1.00, range -4.80 to +3.40 D). For the entire series, 69% of the eyes achieved an uncorrected visual acuity of 20/40 or better, 73% were corrected to within +/- 1.00 D of emmetropia, and 3% were overcorrected by more than +1.00 D. For eyes with low preoperative myopia (-3.00 D and less), 100% achieved an uncorrected visual acuity of 20/40 or better, 97% were corrected to within +/- 1.00 D of emmetropia, and 3% were overcorrected by more than +1.00 D. For eyes with moderate myopia (-3.1 to -5.9 D), 73% achieved an uncorrected visual acuity of 20/40 or better, 81% were corrected to within +/- 1.00 D of emmetropia, and 3% were overcorrected by more than +1.00 D. For eyes with higher preoperative myopia (-6.0 to -11.60 D), 47% achieved an uncorrected visual acuity of 20/40 or better, 45% were corrected to within +/- 1.00 D of emmetropia and 3% were overcorrected by more than +1.00 D. One hundred eyes with a follow-up of 2 years or greater were studied for stability; 77% changed by less than 1.00 D from the 1 year value; 17% changed by 1.00 D or more in the hyperopic direction; 6% changed by 1.00 D or more in the myopic direction. There were no vision threatening complications and only one eye had a postoperative best spectacle corrected visual acuity of less than 20/40.

Adult↗
PubMedDate not supplied

The 1990 wage case.

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Collective Bargaining↗
PubMedDate not supplied

Effect of ascorbic acid on the disease caused by Escherichia coli challenge infection.

In a series of experiments, leghorn-type chickens were fed diets containing from 0 to 880 mg of ascorbic acid/kg of feed beginning 1 day before air-sac challenge with Escherichia coli. Infection occurred in 46/60 (76%) of the controls and in 12/63 (19%) of those given feed containing 330 mg of ascorbic acid/kg. Levels of ascorbic acid above and below 330 mg/kg feed were less effective.

Animals↗
PubMedDate not supplied

Satisfaction guaranteed.

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Community Health Nursing↗
PubMedDate not supplied

The use of pure FSH alone or in combination for ovulation stimulation in in vitro fertilization.

The experience of the Norfolk Program, from the beginning of 1981 until mid 1984, is reviewed. Two groups of patients are compared. The initial experience goes from the very beginning until early 1984 in which knowledge has accumulated; the patients treated afterwards up to mid 1984 where the previous experience was used to monitor them in a more accurate way is reviewed as a separate category. Different protocols, in each group, are compared: concomitant combination of hFSH/hMG (protocol # 1), sequential combination of the two gonadotropins (protocol # 2), and pure FSH administration (protocol # 3). Several parameters were used in the evaluation of the results: 1) day of laparoscopy, 2) volume of the follicles obtained, 3) number of preovulatory oocytes obtained, 4) number of immature oocytes obtained, 5) number of atretic oocytes induced, 6) number of oocytes with abnormal zona pellucida, 7) fertilization rate of preovulatory and immature oocytes, 8) abnormal fertilization rate of preovulatory and immature oocytes, 9) cleavage rate of the normally fertilized preovulatory immature oocytes, 10) transfer rate, single and multiple, 11) follicular and luteal phases as evaluated by estradiol levels in the preovulatory phase and by E2 and progesterone in the post ovulatory phase, 12) pregnancy rate. Pure FSH seems to prolong somewhat the follicular phase. Preovulatory oocytes derived from small follicles may originate pregnancies that may end in abortion. The concomitant combination rendered a larger number of preovulatory oocytes. The number of immature oocytes tend to be higher in the pure FSH stimulated group, but this seems to depend on the way FSH is used. The normal fertilization rate for preovulatory oocytes tends to be similar as the criteria used in the stimulation protocol improved. The abnormal fertilization rate for both types of oocytes decreased in the latest series. The number of embryos transferred was higher in the concomitant combination stimulation. Shortening the hMG/hCG interval in the pure FSH category seems to induce a deficient follicular phase except in cases with rapid high response. When using the hFSH/hMG combination the values of estradiol in the follicular phase tend to be much higher than when the original pure hMG protocol is used. This does not seem to be true when pure FSH stimulation is used. The number of multiple transfers increased substantially in both types of stimulation as experience increased.(ABSTRACT TRUNCATED AT 400 WORDS)

Chorionic Gonadotropin↗
PubMedDate not supplied

Identifying the nonmedical concerns of patients with ocular melanoma.

1. The task of enhancing patients' quality of life begins with identifying their needs and concerns. This process requires a knowledge base of the needs, problems, and barriers patients face as they struggle with the physical, psychological, and social sequelae of cancer. 2. To enhance knowledge of the psychosocial consequences of ocular melanoma and to facilitate supportive care planning, a study was initiated to identify patients' needs arising from the symptom management and nonmedical concerns of these patients, barriers to resolving these needs, and patients' service preferences. 3. The results indicate that the expressed needs inventory and the scales measuring unexpressed needs represent a valid and reliable approach to needs assessment, and that this approach is able to identify the needs resulting from patients' symptom management and nonmedical concerns.

Clinical Nursing Research↗
PubMedDate not supplied

Plasma lipids, lipoproteins, and mammographic densities.

There is strong evidence that the risk of breast cancer in populations is influenced by environmental factors. Plasma lipids and lipoproteins are known to be under environmental control and to have epidemiological and/or biological characteristics that suggest they may be relevant to breast cancer risk. The purpose of the study described here was to determine whether plasma lipids, lipoproteins, and the urinary excretion of the mutagen malondialdehyde (MDA) are associated with differences in breast cancer risk. We measured plasma lipids, lipoproteins, and urinary MDA in women without breast cancer but with different degrees of density of the breast parenchyma on mammography, a strong risk factor for breast cancer. Mammograms from 273 premenopausal women were digitized to high spatial resolution by a scanning densitometer, and images were analyzed to quantify the extent of density. The percentage of the breast occupied by mammographic densities was found, after controlling for the effects of age and the Quetelet index of obesity, to be significantly associated with plasma levels of high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride, apoprotein B, and urinary excretion of MDA. A multivariate model comprised of the Quetelet index of obesity, alcohol consumption, apoprotein B, parity, daily MDA excretion, and the skinfold thickness sum accounted for 36% of the variation in breast density. These results suggest that differences in lipid metabolism are associated with differences in breast cancer risk as defined by mammographic densities. These findings are consistent with several other observations that show a relationship between plasma lipids, lipoproteins, and risk factors for breast cancer.

Adult↗