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Biomedical subjects

D J Lisk

Publications and source records attributed to D J Lisk.

At least 91 records · Page 5Linked to original sources
PubMed1982

Toxicologic studies in growing sheep fed silage corn cultured on municipal sludge-amended acid subsoil.

Field corn was grown on subsoil, pH 5.5, that had been amended with 100 dry tons per acre (224 metric tons per hectare) of municipal sewage sludge from Syracuse, New York. The corn plants containing 3.88 ppm dry weight of cadmium were field-chopped and ensiled, and the silage was fed to growing sheep for 225 d. The sheep fed the sludge-grown corn silage showed a significantly (10 higher feed efficiency, (2) higher hepatic microsomal p-nitroanisole O-demethylase activity, and (3) higher concentrations of cadmium in liver and kidney and nickel in kidney as compared to the control animals. No significant treatment effects were observed in mutagenic responses for animal feed or feces samples. No consistent treatment effects were noted during histopathologic examination of sheep tissues.

Animal Feed↗
PubMed1982

Cadmium and nickel in smoke of cigarettes prepared from tobacco cultured on municipal sludge-amended soil.

Cigarettes prepared from tobacco grown on municipal sludge-amended soil were smoked, and the mainstream particulates and gaseous fractions were analyzed for total cadmium and nickel content. Sludge-grown and control (soil-grown) tobaccos contained, respectively, 67.4 and 3.18 ppm of cadmium and 19.4 and 1.29 ppm of nickel. The quantities of cadmium (microgram per cigarette) found in the mainstream particulate and gaseous fractions were, respectively, 6.67 and 0.04 for the sludge-grown and 0.21 and 0.03 for the control treatments. The quantities of nickel (microgram per cigarette) found in the mainstream particulates and gaseous fractions were, respectively, 0.11 and 0.07 for the sludge-grown and 0.01 and 0.01 for the control treatments. The potential public health implications of these results and modifying factors are discussed.

Cadmium↗
PubMed1982

Toxicologic studies with swine fed corn grown on municipal sewage sludge-amended soil.

Over a 3-yr period 336 MT/ha of dried sewage sludge, from a municipal waste treatment plant, was applied in liquid form to land subsequently used to grow corn. The sludge contained 115 mg Cd, 4,200 mg Zn and 538 mg Ni/kg dry matter and comprised the solids remaining after treatment of the waste waters of approximately 260 industries as well as domestic users. Corn grain harvested from the plot amended with sewage sludge (SA corn) or corn grown on a plot without sludge addition (control corn) was fed to a total of 56 pigs to determine the effect on growth performance and parameters indicative of toxicity. Each treatment consisted of seven pens of four pigs each with an average initial weight of 17.6 kg. The growth trial was terminated when pigs weighed approximately 90 kg. No differences were observed between treatment groups for average daily gain, feed: gain ratio or daily feed intake. Higher (P less than .01) concentrations of Cd, Ni and Zn were found in SA corn compared with the control corn. This resulted in higher (P less than .01) concentrations of Cd in kidney and liver and Ni in kidney of pigs fed SA corn as compared with pigs fed control corn. No significant differences were observed in Cd or Ni concentrations in muscle or in hepatic microsomal mixed-function oxidase (MFO) activity and liver:body weight ratios, which is indicative of the absence or low levels of organic toxicants in SA corn. In addition, no significant treatment effects were observed when corn, feces and urine samples were evaluated for the presence of mutagenic substances. Histopathologic analysis of various tissues for lesions demonstrated that pigs fed SA corn were not adversely affected.

Animals↗
PubMed1982

Gas-liquid chromatographic determination of fenvalerate insecticide residues in processed apple products and by-products.

Apples from trees treated in the field at 2-week intervals (9 foliar applications) with the synthetic pyrethroid insecticide fenvalerate (cyano(3-phenoxyphenyl) methyl 4-chloro-alpha-(1-methylethyl)-benzeneacetate) were processed into apple sauce, juice, pomace, and peels plus cores. Gas-liquid chromatographic analysis of the commodities for fenvalerate showed the sauce and juice to be essentially residue-free, the whole apples to contain about 0.4 ppm, and the pomace and peels plus cores to contain about 2 and 1.5 ppm, respectively. Agreement among 5 laboratories using modifications of the same basic method was good.

Beverages↗
PubMed1981

Elemental content of vegetables and millet grown in potted soil amended with lignite fly ash.

Vegetables and millet were grown to maturity in potted soil amended with 10% (by weight) of lignite fly ash. Analysis of the ash, soil, and crops for 40 elements showed Al, As, B, Mg, Mo, Rb, and Se to be absorbed at higher levels by the ash-grown plants than the controls in most instances. Selenium was of most concern, because of its toxicity and degree of plant uptake.

Carbon↗
PubMed1981

Cement kiln dusts as a selenium source in sheep rations.

Cement dust has been found to be a source of selenium when included in the rations of sheep. In the work reported, rations including 3% by weight of cement dusts were fed to sheep for 165 days. The dust were taken from 3 collectors located at progressively greater distances from the coal-fired end of the kiln. Selenium levels and blood and tissues of the animals fed the cement dusts increased significantly above those of the control sheep. No tissue abnormalities were observed in animals receiving any of the treatment rations. The source of selenium is believed to derive from its content of fly ash as a result of the coal combustion during cement manufacture.

Animal Feed↗
PubMed1980

Soft coal fly ash as a source of selenium in unpelleted sheep rations.

Soft coal fly ash has been found to be a source of selenium when included in the rations of cows and hogs. In the work reported, a ration including 10% by weight of soft coal fly ash was fed to sheep for 135 days. Selenium levels in blood and tissues of the animals fed the fly ash ration increased significantly above the control sheep. No adverse clinical signs or lesions were observed in the animals on either treatment.

Animal Feed↗
PubMed1980

Increasing selenium in bovine blood by feed supplements or selenium injections.

A study was made of the relative effectiveness of including various feed supplements or selenium injections on increasing the blood level of selenium in pregnant Holstein cows. The dietary treatment included the addition of soft coal fly ash, western grown grains, high selenium sweet clover or sodium selenite to the rations. Whereas each of the treatments caused a progressive increase in blood selenium the addition of 4% by weight of fly ash to the ration raised the concentration of selenium in blood the highest. Increases in the concentration of selenium in milk as a result of the treatments were very small.

Administration, Oral↗
PubMed1980

Selenium retention in tissues of swine fed carcasses of pigs grown on diets containing sodium selenite or high selenium white sweet clover grown on fly ash.

Growing pigs were fed diets containing 5 or 10% white sweet clover, and 0, 3.5 or 7.0 ppm selenium (Se) supplied as sodium selenite (Na2SeO3) or occurring naturally in white sweet clover harvested from a coal fly ash dump. Ground carcasses of these pigs were included in corn meal diets at 23% and fed back to pigs. Compared to the pigs fed the high Se, fly ash-grown clover diets, the pigs fed Na2SeO3 diets had higher blood Se levels but lower Se concentrations in kidney, liver and skeletal muscle. Tissues of the pigs which were fed carcasses of the high Se clover-fed pigs had higher Se concentrations than those of the pigs fed carcasses of the Na2SeO3 - fed pigs.

Animal Feed↗