Search PubMed⌕ Search

Biomedical subjects

D J Hall

Publications and source records attributed to D J Hall.

At least 127 records · Page 7Linked to original sources
PubMed1981

Quantitative evaluation of nasal airflow in relation to facial morphology.

This study examines the relationship between facial morphology and nasal respiration. Nasal resistance to expiratory airflow, average volume flow rate, and temporal characteristics of the respiratory cycle were measured for twenty-eight adults. Subjects were categorized as having (1) normal facial proportions with competent lips (n = 10), (2) normal facial proportions with incompetent lips (n = 9), and (3) long vertical face height (n = 9). Results indicate that the three groups do not differ significantly in terms of nasal airflow. Lip incompetence is not synonymous with mouth breathing. Although long-faced subjects as a group had a higher mean value of nasal resistance, the range of variation was so great as to preclude the diagnosis of nasal obstruction from an assessment of facial morphology.

Adolescent↗
PubMed1981

Computed tomography in the evaluation of carcinoma of the ovary.

Over a 26 month period, 34 patients with histologically proven ovarian malignancy were studied by computed tomography (CT). In nine patients, CT was obtained for evaluation of a pelvic or abdominal mass. Computed tomography was diagnostic of ovarian malignancy in seven and indeterminate regarding the origin of the tumor in two patients. Ten patients were evaluated by CT in order to rule out recurrent ovarian neoplasm. Disease free intervals prior to CT ranged from 6 to 36 months with an average of 18 months. In eight surgically proven cases, CT was true positive for recurrent tumor in six patients, true negative in one, and false positive in one. In 20 patients, serial CT examinations were valuable in the objective assessment of measurable tumor response following chemotherapy and radiation therapy. A major limitation of CT was its inability to detect peritoneal and liver surface implants smaller than 2 cm in size.

Cystadenocarcinoma↗
PubMed1981

Recurrent carcinoma of the cervix: CT diagnosis.

Thirty-three patients with previously treated carcinoma of the cervix were evaluated with computed tomography (CT) for recurrent tumor. Recurrent carcinoma was confirmed in 29 patients and radiation sequelae were documented in four patients. CT diagnosis was true positive for recurrence in 82%, false negative in 6%, false positive in 6%, and equivocal in 6%. False-negative examinations were due to small, superficial, clinically detectable tumor foci in the vagina or perineum. False-positive and equivocal examinations were due to radiation changes in the true pelvis. CT was valuable in assessing central pelvic tumor recurrence, parametrial and sidewall tumor extension, pelvic and paraaortic lymphadenopathy, and the obstruction site of hydronephrosis. Since CT detected recurrent tumor in 27 of 29 patients (sensitivity 93%), it is a valuable noninvasive technique to screen patients with suspected recurrent tumor and to evaluate those with known recurrence for disease extent and subsequent therapy.

Adult↗
PubMed1980

Cephalometric diagnosis and surgical-orthodontic correction of apertognathia.

Nineteen postadolescent white woman with uncorrected Class I molar and/or canine occlusion were compared cephalometrically to thirteen postadolescent white women with skeletal apertognathia that was later corrected by a combination of surgical procedures, the common denominator being maxillary posterior superior repositioning. The cephalometric tracings were compared statistically by evaluating the study group preoperatively, immediately postoperatively, and at a long-term follow-up appointment. The results indicate that there is a statistical difference in certain important measurements between normal persons and preoperative apertognathic patients with the deformity identified in the dentoalveolar complex of the maxilla. Posterior maxillary superior repositioning tends to correct this skeletal deformity, with postoperative measurements approaching the normal values. The correction proved to be stable over a mean follow-up period of 19 months (range, 7 to 30 months).

Adolescent↗
PubMed1980

Quantitation of [3H] thymidine uptake by stimulated human lymphocytes.

We have investigated the relationship between cell numbers and the amount of tritiated thymidine ([3H]TdR) taken up by stimulated human peripheral lymphocytes, as a function both of labeling time and of the specific activity of the thymidine. Cells responding either to mitogens or to allogenic cells show simple first order kinetics for the uptake of thymidine. Fitting the data to a Michaelis-Menten type of model, we observe for labeling times of 12 hr and longer, non-competitive inhibition of thymidine uptake by increased specific activity of tritium label, regardless of the mode of stimulation. However, for an individual responder in MLC at any arbitrary but fixed specific activity, dose of [3H]TdR and labeling interval, we still observe a linear relationship between cell mass and incorporated label. In contrast, if specific responding combinations in mixed lymphocyte culture are compared, the inhibition by specific activity at longer time intervals becomes significant and influences the quantitative interpretation of results. Specific activities of less than 10 Ci/mmole and labeling times of 6 hr or less avoid inhibition and ensure a linear relationship between dividing cell number and CPM (counts per minute recorded) of incorporated label.

Cells, Cultured↗
PubMed1980

Paranoid states of middle life. Familial occurrence and relationship to schizophrenia.

Paranoid states beginning in middle life were selected from a case register. A search among the sibs of those probands uncovered no paranoid states and schizophrenia was no more common than in the general population. The implications for the aetiology of paranoid states and for the relationship between these and schizophrenia are discussed.

Adult↗
PubMed1980

Outpatient endometrial sampling.

Endometrial sampling is an easily performed, economical, and accurate outpatient diagnostic procedure with wide application in gynecology. It is readily accepted by patients as an alternative to inpatient dilatation and curettage. The information which it provides relative to endometrial histology enables the physician to detect premalignant and malignant processes, to be precise in making diagnoses, and to document the results of therapy.

Ambulatory Care↗
PubMed1980

Primary malignant melanoma of the uterine cervix.

A case of primary malignant melanoma of the cervix is presented that was treated by radical pelvic surgery. The cytology, histology and electron microscopy of the lesion are presented with a brief clinical discussion.

Adult↗