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Biomedical subjects

D I Williams

Publications and source records attributed to D I Williams.

At least 73 records · Page 4Linked to original sources

The micropenis syndrome: clinical observations and expectations for growth.

We reviewed 34 genotypic male subjects with a true micropenis to determine the clinical situations in which micropenis is encountered and the types of therapy resulting in growth. The relationship of clinically functioning testicular tissue to growth is noted. Diagnostic modalities, including human chorionic gonadotropin stimulation, are discussed, as well as a plan for individual assessment and therapy.

Chorionic Gonadotropin↗

The place of alpha-blocking drugs in the treatment of children with neuropathic bladders.

Phenoxybenzamine, an alpha-adrenergic blocking drug has been evaluated in the treatment of 14 children with neuropathic bladder dysfunction. The majority of children treated showed significant reductions of residual urine and urethral closure pressure. A useful clinical response in terms of improved bladder control was obtained in over half the patients. Children with mild radiological changes in the upper urinary tracts showed radiological improvement but those with marked changes did not improve. The drug is generally well tolerated but side-effects of postural hypotension, lethargy and nausea may occur.

Child↗

Anterior detrusor tube repair for urinary incontinence in children.

The technique, complications and results of an anterior detrusor tube repair for urinary incontinence in children is described. It appears that this procedure is appropriate only for selected cases of urinary incontinence but that it is an operation which should be within the paediatric urologist's repertoire. It is simple to perform, but care should be taken, by omental packing, to prevent a sharp posterior lip to the newly formed bladder neck.

Child↗

Circumcaval ureter: a report of four cases in children with a review of the literature and a new classification.

4 cases of circumcaval ureter presenting in childhood are reported. A review of the literature reveals that most cases recieve attention only later in life at a time when ureteric changes are not so readily reversible. A study of the course of the ureter reveals that 2 forms can be distinguished: a common Type I with a slter reveals that 2 forms can be distinguished: a common Type I with a low loop and kinking of the proximal ureter producing obstruction and a rare Type II with a high loop where there is no kinking and no obstruction. Ureteric remodelling on the ordinary principles formulated for congenital obstructions can give good results.

Adolescent↗

The prognosis of pelviureteric obstruction in childhood: a review of 190 cases.

190 children with pelviureteric obstruction are reviewed. Their symptoms are analysed and the pre- and post-operative radiographic appearances are assessed. The results are very encouraging with a clinical improvement in the majority of patients, free ureteric drainage in almost all and an improvement in the calyceal pattern in 65.9%.

Adolescent↗

Bisalbuminaemia.

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Adult↗

Acnitis.

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Calcinosis↗