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Biomedical subjects

D Hallberg

Publications and source records attributed to D Hallberg.

At least 73 records · Page 4Linked to original sources
PubMed1975

Skin reduction plasties following intestinal shunt operations for treatment of obesity.

A unique group of more than 100 selected cases were treated surgically for massive obesity, a mal-absorption syndrome, by an intestinal shunt used to obtain significant weight reduction. The loss of skin elasticity of the slimming patient leads to a "redundant skin syndrome" creating dermatologic-cosmetic as well as psychiatric problems. A series of reductive skin plasties were performed beginning when the patient's body weight had been stable for some months. The redundant skin was found mainly in two contralateral areas: on both sides of the axillae: on the medial aspect of the upper arm and laterally below the breast, and on both sides of the inguinal ligament, on the lower abdomen and on the medial aspect of the thigh. Thirty-eight patients of the group had skin reduction plasties. The operations were performed on each site separately with a few months' interval. Operative techniques and results are presented.

Adolescent↗
PubMed1975

Fatty acid patterns of serum triglycerides and subcutaneous adipose tissues after ileal bypass in obesity.

A group of 9 obese subjects with a mean body weight of 140 kg was treated for their obesity with a jejuno-ileal intestinal shunt. During the first post-operative year their mean body weight decreased to 100 kg. Fatty acid patterns of triglycerides inserum and subcutaneous adipose tissue were studied at intervals during one year after surgery. Myristic and palmitic acids' contents of serum triglycerides were found to decrease during this period of time, whereas the fatty acid pattern of triglycerides in adipose tissue was practically unchanged. Triglycerides, cholesterol, albumin, and lactate dehydrogenase in serum decreased during the first year after operation, whereas aminotransferases showed a transient elevation. It is put forward that these findings are consistent with starvation rather than liver dysfunction.

Adipose Tissue↗
PubMed1975

Amino acid pattern in plasma before and after jejuno-ileal shunt operation for obesity.

The amino acid pattern in plasma was studied in a reference group (n=26) and in three groups of massive obese subjects (n=9, 8, and 9 respectively) before and at intervals after jejuno-ileostomy. The obese subjects had preoperatively an amino acid pattern significantly different from that in the reference group. The concentrations of lysine, tyrosine, 1/2 cystine, and glutamic acids were higher, and aspargin, glutamine, serine, and glycine were lower than in the reference group. During the post-operative period the amino acid pattern changed significantly; thus serine, glycine, and taurine increased and valine, lysine, leucine, tryptophan, thyrosine, 1/2 cystine, and citrulline decreased. The amino acid pattern in the obese group with the longest post-operative observation time and a stable body weight differed significantly from that in the reference group only with regard to a low valine concentration and high concentration of taurine and glutamatic acid.

Adult↗
PubMed1975

Some somatic complications after small intestinal bypass operations for obesity. Possible factors of significance in the incidence.

The complications after intestinal bypass operations in 103 massively obese subjects were recorded postoperatively for a maximum of 5 years. The surgical procedures were jejuno-ileostomy, end-to-side (op. I) in 35, and end-to-end with ileocaecostomy (op. II) in 68 cases. Wound dehiscence was the cause of the sole early postoperative death. The early complications found were those commonly seen after abdominal surgery, namely wound infection (n=24), wound dehiscence (n=5), anastomotic leak (n=2), leg thrombosis (n=2). One of the latter 2 patients probably also had pulmonary embolism. In 6 cases early intestinal obstruction occurred; 3 of them required reoperation. The late complications were divided into unspecific and specific in relation to the surgically induced malabsorption. Their incidence was analysed in 80 subjects observed for longer than 1.5 years after the operation. Unspecific late complications consisted of intestinal obstruction in 5 cases and incidional hernias in 18 cases. Intussusception was not seen. There seemed to be no increase in the incidence of gallstone disease or gastroduodenal ulcer after the operation. Specific late complications were electrolyte disturbances (ED) in 13, signs of liver injury (LI) in 9, urinary-tract calculi (UTC) in 15, and immunopathy (IM) in 19 cases. The IM group had skin rashes, arthralgia, and fever. Besides these somatic complications, a number of specific pyschictric complications were also observed (not published). Three subjects died after the operation with signs of liver insufficiency. The following factors were found to be of importance in the occurence of the specific complications ED and LI: 1. The presence of preoperative abnormalities in serum-electrolyte concentration and pathological liver tests, mainly occuring in the heavies patients. 2. Most ED and LI occurred during the period of main weight loss, in general during the first postoperative year. ED and LI did not appear after body weight had stabilised. 3. The rate of weight loss: ED and LI occurred, with a few exceptions, in the subjects with a rate of weight loss higher than 0.0130 weight-index units per week during the period of constant weight loss (see article).

Body Height↗