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Biomedical subjects

D Galili

Publications and source records attributed to D Galili.

54 records · Page 3Linked to original sources

Intraligamentary anesthesia--a histological study.

Intraligamentary dental anesthesia is considered to be an efficient and clinically safe anesthetic technique, and as a result, is widely used. The present study evaluates histologically any possible damage to the periodontal apparatus, in baboon monkeys. The damage induced by the injection needle and/or the anesthetic solution, which was injected under high pressure, was localized, minor and reversible. In most of the specimens, all signs of damage disappeared within 8 days following injection. In others, some granulation tissue was evident in the lamina propria 15 days following injection. However, no bone or cemental damage was observed.

Anesthesia, Dental↗

The attitude of chronic hemodialysis patients toward dental treatment.

Dental care of hemodialysis and renal-transplant patients involves various psychological parameters. Their basic illness affects their dental anxiety, self-image, active motivation to cope with difficulties, and appreciation of oral health. These parameters were measured by four specific questionnaires in fifty subjects: 25 renal patients and 25 matched controls. Renal patients showed significantly less dental anxiety than did controls, and also less concern about oral health. Patients' coping with difficulties was equal to controls, while their self-image was even more stable. The unusual findings in these patients demonstrate the importance of dentists' cooperation with nephrologists and psychiatrists.

Adult↗

Intraligamentary--intraosseous anesthesia. A radiographic demonstration.

Intraligamentary dental anesthesia has become a widely accepted technique. The periodontal ligament seems to provide easy access to the tooth apex. In the present study, radiopaque material was injected into baboon monkeys. Serial radiographs during incremental injections showed clouding of the crestal bone. The material was seen gradually advancing through the alveolar bone crest, apically. The spread was noticed through the marrow spaces, unexpectedly avoiding the PDL route.

Alveolar Process↗

A modern approach to prevention and treatment of oral bleeding in patients with hepatocellular disease.

Dental treatment for patients with hepatocellular disease constitutes a very complex problem because of their severe bleeding tendency. It seems that bleeding from the oral structures follows organ-specific patterns. The use of systemically administered antifibrinolytic agents, together with the local use of Gelfoam, cyanoacrylate spray, and intraligamentary anesthesia make possible bleeding-inducing procedures without exaggerated hemorrhage. This approach avoids the need for transfusion and hospitalization for dental treatment, making such treatment cheaper and more accessible.

Adult↗

Sensory experience induced by nitrous oxide analgesia.

Preliminary findings on a group of 15 dental patients, treated with nitrous oxide indicated frequent occurrence of several, well-defined sensory experiences related to various modalities. A subsequent controlled experiment carried out on 44 volunteers, inhaling a 35% N2O + 65% O2 sedative gas-mixture as well as O2 alone in two different sessions confirmed a large variety of sensations not related to external stimuli. Taste and/or odor and thermal sensations were often reported as well as changes in auditory or visual perception of the environment in addition to reports of general heaviness, relaxation or tingling.

Adolescent↗

Nitrous oxide analgesia in selected dental patients.

Nitrous oxide analgesia is presented as the analgesic method of choice in medically compromised patients. The resemblance between the action of nitrous oxide and that of morphine is emphasized. The combination of the opiate-like action of nitrous oxide with the advantages of an inhalation technique makes it preferable and superior to parenteral opiate administration. It may thus be termed as an inhalation "opiate".Since its introduction into clinical use by Wells in 1844 (1), nitrous oxide (N(2)0) has been applied as an anesthetic and analgesic agent in various medical situations, including dentistry (2). The development of equipment affording safe administration of accurate concentrations of either pre-mixed or adjustable N(2)0 and oxygen enabled the application of "relative analgesia" as an important technique in the relief of pain. The pharmacological action and analgesic properties of N(2)0 received renewed interest after Berkowitz et al (3) showed the resemblance between its mode of action and that of opiates. Recent human and animal studies indicated that N(2)0 activates the endogenous opiate system(s) in a manner similar to that of morphine (4). The availability of an analgesic gas which, on the one hand, mimics opiate action whilst on the other hand its administration is continuously adjustable, as opposed to other modes of sedation, makes it into an ideal adjunct in dental procedures. Owing to its minimal side effects, the use of N(2)0 is especially recommended in the management of anxious children and medically compromised patients.This report presents three illustrative patients in whom nitrous oxide proved to be the drug of choice during dental procedures.

Anesthesia, Dental↗

Comprehensive dental treatment under general anesthesia for patients with homocystinuria.

Continued investigation in genetic biology has helped the medical profession to prevent complications in patients with this defect. Moreover, early diagnosis and treatment are recommended, in order to prevent mental retardation and visual deterioration. Refinement of techniques concerning preparation of the patient for general anesthesia and postoperative care merit further investigation. Simple measures undertaken in the two patients described made the completion of dental treatment possible without serious complications.

Adolescent↗