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Biomedical subjects

D Galili

Publications and source records attributed to D Galili.

At least 37 records · Page 2Linked to original sources

Oral complications in bone marrow transplantation patients: recent advances.

This paper presents some of the oral aspects encountered in bone marrow transplant (BMT) patients, as reflected in recent research conducted in the Department of Oral Medicine. Oral infections caused by Enterobacteriaceae were found to be responsible for a large proportion of positive cultures, during different stages of the transplantation process. Mucositis was constantly detected concomitant with the infections. It correlated with granulocytopenia and fever. The mucositis improved together with the immune system reconstitution. Immunoglobulins in saliva of BMT patients showed a drastic reduction following the patients' conditioning protocol and a return to normal levels soon after the transplantation. IgA, IgM and IgG were studied. Saliva was also shown to play an important role in the fibrinolytic system, through its plasminogen activator inhibitory contents. It seems that the active molecules are contained in the oral epithelial cells.

Agranulocytosis↗

Dental treatment in a patient with malignant pheochromocytoma and severe uncontrolled high blood pressure.

A young female with severely uncontrolled hypertension suspected to result from malignant pheochromocytoma underwent combined medical and dental care for the treatment of acute dental pain. The dental treatment was performed with the patient under intravenous sedation and careful perioperative management with the use of high doses of alpha and beta receptor blocking agents. The procedure was completed without intraoperative problems and an uneventful posttreatment course.

Adrenal Gland Neoplasms↗

Dental treatment in very high risk patients with active ischemic heart disease.

A new method of predental treatment and management for patients with active ischemic heart disease is reported. Patients with unstable angina pectoris or who have just had a myocardial infarction underwent full treatment for pain-induced dental problems, with the use of an incremental three-level antiangina and antianxiety medication: before dental treatment; in the waiting room, and c) during dental treatment. The setting was a tertiary referral oral medical service and hospital dental clinic. Twenty-six patients were treated, 16 men, 10 women, ranging in age from 45 to 68 years. Ten patients with unstable angina pectoris and 16 patients less than 3 months after a myocardial infarction. All patients underwent comprehensive dental treatment. Good cardiovascular control was achieved, and all the procedures were uneventfully completed. This study indicates the need to reconsider the absolute versus relative contraindications for dental treatment in patients with active ischemic heart disease and recommends the use of a gradual three-level therapy.

Aged↗

Gram-negative enteric bacteria in the oral cavity of leukemia patients.

We examined changes in the bacterial flora in hospitalized patients with leukemia. This study placed special emphasis on enteric microorganisms and their relation to the general status of the patient. One hundred thirty bacterial cultures from 16 leukemia patients and 16 control subjects, were obtained. The organisms were isolated on MacConkey agar and identified by the API-20E system. Enteric microorganisms were isolated from 62.2% of the leukemia patients as compared with 28% from the control group (p < 0.001). The enteric positive cultures were identified as Klebsiella (42.7%), Enterobacter (18.8%), and Pseudomonas (15.6%). In contrast to the negative cultures (1342), enteric microorganisms were cultured from 2948 specimens (p < 0.005).

Adult↗

Pulp narrowing in renal end stage and transplanted patients.

A comparison of relative dental pulp size in chronic renal disease patients with dental pulp size in healthy controls revealed a significant pulp narrowing in the kidney disease group (n = 44). A strong correlation between the chronicity of the renal disease and the pulp narrowing was found in the premolar and molar teeth of the tested group. A review of the literature concerning pulp narrowing is also presented.

Adolescent↗

The attitude of patients at risk for infective endocarditis toward dental treatment.

This study deals with four major characteristics that directly affect motivation and attitude of patients at risk for infective endocarditis (IE) toward oro-dental health. Dental anxiety, self image, recognized importance of oro-dental care, and active coping were self-assessed by 25 patients at risk for IE and by a matched control group. The study group demonstrated less dental anxiety, lower self image and higher levels of recognized importance of oro-dental care than the controls, while active coping did not differ between the two groups. A review of the relevant literature is also presented.

Adult↗

Energy requirement of feed-restricted broiler breeder pullets.

The energy requirements for growth and maintenance of broiler pullets were studied during a 17-wk growing period. Four flocks of commercial broiler replacement pullets, housed in conventional poultry houses, received a restricted amount of feed on 4 or 5 days a week, and pullet growth was recorded. The energy needs for maintenance and body weight gain under a feed restriction regimen was calculated using a model based on metabolic body weight and weight gain described by Hurwitz and coworkers. Average daily body weight gain for the entire experimental period was 13.7 g; the daily energy intake increased with age from 114 kcal/day at 3 wk of age to approximately 270 kcal/day at 20 wk. The estimated daily metabolizable energy requirement for maintenance was 1.57 kcal/g of body weight67 and for growth, .71 kcal/g of body weight. It was concluded that the energy requirement for birds under a feed restriction regimen is considerably lower than those under ad libitum feeding.

Aging↗

Oral clinicopathologic manifestations in maple syrup urine disease.

Maple syrup urine disease is a rare inborn error of metabolism that manifests mainly by neurologic deterioration, coma, and death in early childhood. Oral manifestations described in this article were mostly gingival enlargement and rampant caries, while histopathologic findings revealed a picture compatible osteomyelitis.

Adolescent↗

Juvenile recurrent parotitis: clinicoradiologic follow-up study and the beneficial effect of sialography.

In twenty-two children juvenile recurrent parotitis (JRP) was diagnosed on the basis of age at onset, duration of parotid swelling episodes, frequency of attacks, lack of pus formation, and typical sialograms. Age at onset and severity of the disease varied widely. There was a high incidence of upper respiratory tract infection, and in some cases a familial history of JRP was noted. The sialograms revealed acinar and ductal atrophy and severe sialectasis. A dominant feature was impaired glandular function. The follow-up period was notable for a striking decrease in the number of incidents of glandular swelling regardless of the patient's age at the time of his or her first visit to our clinic. Since drug treatment was administered prior to our first examination and no medicaments were prescribed by us, the improvement in the clinical status of the patients is attributed to the sialographic procedures.

Child↗

Temperature preference of drinking water in rats.

The water temperature preference of adult male albino rats was studied. Deprived and normally hydrated animals were exposed at peak hours of consumption to a choice between 12 degrees C and 30 degrees C water or to 12 degrees C and 34 degrees C water. Food intake was not restricted. There was a clear preference for the warmer water. It is concluded that oropharyngeal temperature cues influence water intake.

Animals↗

Eruption of rootless teeth in congenital renal disease.

Eruption of rootless mandibular premolars and other dental defects in a girl suffering from congenital kidney disease are described. The successful management of these excessively mobile teeth allowed them to develop roots of sufficient length. Hypotheses of tooth emergence are viewed in the light of these rootless eruptions.

Bicuspid↗

Spontaneous regeneration of the parotid salivary gland following juvenile recurrent parotitis.

Sialograms of an 18-year-old female patient known to suffer from juvenile recurrent parotitis (JRP) disclosed the destructive glandular changes typical of the disease. During the 10 years subsequent to the sialographic examination, the patient did not experience any further attacks of JRP. Sialograms carried out when the patient was 28 years of age demonstrated a normal gland. This case illustrates that a damaged parotid gland is capable of regeneration following JRP.

Adolescent↗