Early detection of cancer in women.
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Biomedical subjects
Publications and source records attributed to D C Brown.
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We describe a patient with histiocytosis X and compulsive water drinking. The association of diabetes insipidus with histiocytosis X is well recognized, and this patient was initially considered to have diabetes insipidus. It was only after further testing that the proper diagnosis was made.
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Eighteen male diabetic patients with a mean age of 48.5 years and end-stage renal disease were maintained on chronic hemodialysis for a mean duration of 15.2 months. The cumulative survival rate for the first year was 86%. Their diabetes was no more difficult to control after starting hemodialysis. Cardiovascular complications accounted for the two deaths and most of the management problems. Patient rehabilitation was considered to be satisfactory. It is concluded that chronic hemodialysis can be a suitable form of therapy in this group of patients.
A group of 37 patients with 39 renal transplants were studied from January 1971 to June 1974, in which 32 were considered at high risk by well defined cardiovascular, gastrointestinal, cerebral vascular, or pulmonary disease or age categories. Three of the 37 patients have died, and two patients in the high risk group, 92 per cent. Eighty-eight per cent of the entire group have functioning kidneys at present, and 93 per cent of those in the high risk group have functioning kidneys. Evaluation of pretransplant mixed lymphocyte cultures, HL-A antigen, and immune responder status; close follow-up observation of lymphocyte culture and humoral responses by in vitro testing; and the use of antilymphoblast globulin are considered to be the reasons for the improved results.
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