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Biomedical subjects

D Beyer

Publications and source records attributed to D Beyer.

At least 109 records · Page 6Linked to original sources

[Chemotherapy schedule for the management of metastasizing gastric cancer. Methotrexate, adriamycin and 5-fluorouracil].

The possible effectiveness of methotrexate, 5-fluorouracil and adriamycin was tested in a phase I/II study of patients with metastasising gastric carcinoma. complete of partial remission occurred in 19 of 30 patients (approximately 63%). Two of 30 patients had complete remission. Median survival time of patients with remission cannot as yet be determined: about 68% are still alive after 17 months. Median survival time of patients with advanced tumour was only five months. The difference in survival curve is statistically significant (P less than 0.05). The study is continuing.

Adult↗

Conventional roentgen diagnosis of mediastinal lymphadenopathy. Review article (part one).

Although CT has significantly improved the imaging of space occupying mediastinal processes, it cannot be the first diagnostic step for reasons of cost, capacity and radiation exposure. Therefore the conventional chest examination with biplane films, film tomography and esophagogram continues to be the basic roentgen procedure. The basis of the conventional studies is the analysis of the pleuro-mediastinal interfaces which represent the lateral mediastinal borders. This paper describes the roentgen-morphologic aspects of enlarged lymph nodes in the mediastinal compartments as far as they can be detected with conventional studies. The differential diagnoses are discussed and recognition of early and discrete lesions is particularly emphasized.

Adult↗

[The right paratracheal stripe--an aid in the evaluation of upper mediastinal disease (author's transl)].

Normal roentgen anatomy, physiologic variations and pathologic changes of both shape and size of the right paratracheal stripe (RPS) are discussed. The broad spectrum of common and rare differential diagnosis of the pathologic RPS is demonstrated. There are space occupying lesions in the middle compartment of the upper mediastinum, originating from the trachea or the paratracheal tissue including lymph nodes, mediastinal hemorrhage and infection, goiter, vessels and opacifying processes in the adjacent lung and pleura. Under these conditions the RPS may be displaced, widened, irregularly or poorly delineated or obliterated. For correct interpretation clinical findings and history are mandatory.

Hematoma↗

[The roentgen diagnosis of ureterocele-with special reference to the simple orthotopic ureterocele in adults (author's transl)].

The ureterocele is a cystic ballooning of the terminal ureter into the bladder resulting from a congenital weakness of the wall of the lower ureter and a facultative concomitant stenosis of the ureteral orifice. This condition is more frequent in females. The cobra head with its surrounding halo is the most common finding on the excretory urogram in the simple adult ureterocele. In ectopic ureterocele which is principally encountered in children, the ureter terminates either at the bladder neck or in the proximal urethra. The urogram shows filling defect in the bladder which may extend into the female urethra. Ureteral duplication, dilatation of the upper urinary tract, vesico-ureteral reflux, chronic infection and ureteral stones are the most frequent additional findings and complications.

Female↗

[Diagnostic value of abdominal plain films in acute pancreatitis (author's transl)].

Duodenal distension is in connection with corresponding clinical symptoms--the pathognomonic symptom of acute pancreatitis, provided that the film is taken in left lateral decubitus position. In 90% of 192 cases of acute pancreatitis, proven by surgery or high amylase concentration, duodenal distension was diagnosed on the film taken in left lateral decubitus position. If there is the temptative diagnosis of acute pancreatitis and no duodenal distension is demonstrable, this may result from a fluidfilled stomach without air after vomiting or a stomach tube, through which the air may escape. In these cases we give an effervescent powder to demonstrate duodenal distension. The combination of duodenal atony and distension of the small or large bowel is found very often as a sign of spread pancreatic enzymes along definite anatomic planes in the abdomen like transverse mesocolon and small bowel mesentery. The abdominal plain film taken in supine and left lateral decubitus position gives many important informations solving differential diagnostic problems concerning processes in the upper abdomen and determines further diagnostic and therapeutic proceedings considerably.

Acute Disease↗

[Roentgenographic findings of experimental bowel ischaemia is dogs following occlusion of the superior mesenteric artery (author's transl)].

The results after ligation of the superior mesenteric artery in 17 dogs demonstrated, that a "gasless" abdomen and small bowel pseudo-obstruction are unspecific early roentgenographic findings and bowel-wall thickening with narrowed lumen and increased distance to neighbouring loops are a specific early roentgenographic plain-film findings of acute bowel ischemia following mesenteric vascular occlusion. Approximately 10 hours after ligation a combined distension of small and large bowel with dilatation and air-fluid levels is demonstrable as a sign of paralytic ileus with diffuse peritonitis without possibility of differentiation from other causes of this entity. Gas in the bowel wall, in the superior mesenteric vein and in the portal venous system is a late specific plain-film finding resulting from the invasion of gas-forming bacteria into the devitalized bowel wall with advanced gangrene and a sign of infaust prognosis. The results of the plain-film examinations are correlated to angiographic, clinical and laboratory findings, as well as to histology and bacteriology of the ischemic bowel segments.

Acute Disease↗

[Diagnostiv value of pleuro-mediastinal lines and stripes for the radiologic analysis of the mediastinum (part I) (author's transl)].

Conventional x-ray examination of the chest (standard biplane radiograms, spot films, oesophagogram and tomogram) as a non-invasive method is of greatest value in the morphologic diagnosis of mediastinal disease. An important role plays the analysis of the pleuromediastinal lines and stripes which represent the interfaces of mediastinal structures and air containing lung tissue. A bried and systematic survey of their normal and pathologic roentgen anatomy is given and some characteristic examples are demonstrated.

Humans↗

[Diagnostic value of pleuro-mediastinal lines and stripes for the radiologic analysis of the mediastinum (Part II) (author's transl)].

Conventional x-ray examination of the chest (standard biplane radiograms, spot films, oesophagogram and tomogram) as a non-invasive method is of greatest value in the morphologic diagnosis of mediastinal disease. An important role plays the analysis of the pleuromediastinal lines and stripes which represent the interfaces of mediastinal structures and air containing lung tissue. A brief and systematic survey of their normal and pathologic roentgen anatomy is given and some characteristic examples are demonstrated.

Diagnosis, Differential↗

Real-time ultrasonography--an efficient screening method for abdominal and pelvic lymphadenopathy.

Real-time ultrasonography of the abdomen and pelvis was performed in 129 patients with malignant lymphoma and malignant tumors in the course of clinical and pathological staging. The results of real-time ultrasonography were compared with the findings of computed tomography, lymphography and staging laparotomy. Analysis of the data indicated a sensitivity of 72,6% a specificity of 88,8% and an overall accuracy of 78.3%. Real-time ultrasonography, thus, proved to be an efficient screening method for abdominal and pelvic lymphadenopathy. It can reduce the number of lymphographies as well as abdominal CT examinations. Sonographic anatomy of the lymph system and the varying features of lymphomatous involvement in the peritoneal cavity and retroperitoneal space are described, diagnostic pitfalls and the clinical importance of real-time ultrasonography in the diagnostic work-up in patients with adenopathy are detailed.

Abdominal Neoplasms↗

[Bilateral selective renal angiography--a procedure worth while? Report of the incidence of bilateral space-occupying lesions of the kidney in 2721 selective renal angiographies (author's transl)].

Since surgeons can save part of one kidney either by partial resection or reimplantation following "workbench" surgery, it has become increasingly important for the radiologist to demonstrate bilateral space-occupying lesions of the kidneys by bilateral selective angiography, magnification technique and computerized tomography of the kidneys. Fine-needle puncture of the kidney is an important additive technique to solve differential diagnostic problems of avascular, space-occupying renal lesions. Moreover it is a great comfort to the surgeon to know the appearance of both kidneys and may also modify the planned surgical procedure considerably. The incidence of 93 cases of bilateral space occupying lesions of the kidneys, diagnosed in 2721 selective renal angiographies over a period of 13 years, suggests that these entities are more frequent than previously thought.

Adult↗

[The scope and value of translumbar puncture of the renal pelvis (author's transl)].

Percutaneous translumbar pyelography is indicated when excretory urography has failed to demonstrate the cause or site of obstructive uropathy and retrograde pyelography is impossible, undesirable or contraindicated. Under prophylactic treatment with antibiotics translumbar antegrade pyelography is safe, simple and accurate and in selected cases the only diagnostic method to establish exact diagnosis without which appropriate therapy cannot be planned. The method is described and the results of 30 percutaneous translumbar pyelographies obtained from 2680 renal angiographies and 230 punctures of space-occupying lesions over 13 years are reported.

Adult↗