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Biomedical subjects

D Aubert

Publications and source records attributed to D Aubert.

At least 109 records · Page 6Linked to original sources
PubMed1990

[The possibilities of endoscopy in the treatment of various childhood ureteroceles. Apropos of a case].

A case is reported of a large left ureterocele in a duplicated system at the expense of the upper renal pelvis. This ureterocele caused acute pyelonephritis and dilatation of both left systems. It was treated by a classic endoscopic incision of its roof but 18 months later, infecting vesico-renal, grade 2, reflux was developed. This secondary reflux was treated successfully by submeatal polytetrafluoroethylene's (Teflon) paste injection. This new combination of endoscopic techniques proved to be available in this case.

Cystoscopy↗
PubMed1989

[Treatment of vesico-renal reflux in children with endoscopic injection of polytetrafluoroethylene (teflon). Apropos of a series of 100 cases of reflux in 72 children].

The endoscopic subureteral injection of teflon is a new alternative to correct vesicorenal reflux in children. We report the use of this procedure in 72 children presenting with 100 refluxing ureters. In 98 refluxing units the disappearance of reflux was noted on a cystogram performed immediately (success rate: 98%). Followup after 6 months, the reflux recurred in 6 ureters of 52 controlled units (success rate 88.5%). Obstruction was not observed in any cases by repeated ultrasonography. The procedure is simple and reliable. In a failure that required an open operation, surgical reimplantation was not difficult. An endoscopic technique to cure reflux, of various grades would be a valuable alternative. The procedure certainly has advantages for difficult surgical reimplantations (neurogenic bladder, failed reimplant ureters). However, many years follow up are needed to demonstrate lasting success and absence of complications.

Adolescent↗
PubMed1989

[Comparative characteristics of the course of upper obstructive uropathies diagnosed during the perinatal period].

This study compares two groups of 30 infants each, less than 1 month old. The first group includes neonates with ureteropelvic junction obstruction (UPJO) and the second with primary obstructed megaureter without reflux (POM). Diagnosis was made prenatally in 80% of UPJO and 64% of POM. 19 infants with UPJO and 24 with POM no required immediate surgery but have been just supervised. Contrary to UPJO, even grade III POM can present spontaneous resolution. Radiographic improvement is seen generally from 3d to 4th++ months. Tc-DTPA renal diuretic scan (10 cases) and percutaneous pyelomanometry (4 cases) are more accurate tests for UPJO than for POM.

Female↗
PubMed1989

[Endoscopic treatment of vesico-ureteral reflux using a sub-mucous injection of Teflon paste in children. Apropos of 337 patients (491 ureters)].

We reviewed our experience with endoscopic sub-ureteral injection of polytetrafluoroethylene (PTFE) in 337 children (84% females, 16% males). Four hundred and ninety one refluxing ureters were injected (93% primary reflux, 7% secondary reflux after reimplantation, correction of exstrophy of the bladder or neurogenic bladder). Reflux was: - stage I: 7.8% - stage II: 32% - stage III: 38% - stage IV: 20% - stage V: 2.2% Follow-up cystograms were performed one 428 ureters, 6 to 30 months after injection. 80% of children are cured after one injection while 4% required two injections in order to attain the same result. Improvement in the grade of reflux (minimal residual disease) was noted in 10% of the patients and in 6% the procedure failed. In the latter group, 16 children were operated on without difficulty; lymphatic migration of PTFE was noted in two cases. In the 33 patients with secondary reflux, the endoscopic treatment was associated with an 80% cure rate, in the 26 patients presenting a reflux on duplex systems, cure rate was 65%. This is a simple procedure performed on an outpatient basis; in our experience with 491 injections there were no complications at the time of injection nor there any postoperative ureteric obstruction. Endoscopic PTFE injections are less efficient than surgical reimplantation in the treatment of vesico-ureteral reflux. Teflon paste may not be the ideal material, other substances are presently being investigated. This technic is limited by the caliber of the urethra in young boys (Charrière 14).

Adolescent↗
PubMed1989

[Urachal pathology].

Reviewing 5 recent cases, different anatomical and clinical forms of partial or complete urachal persistency are described: patent urachus, urachal cyst, urachal sinus and urachal diverticulum. The risk of late malignant evolution of this embryonic vestige justifies radical surgical removal at time of diagnosis.

Child, Preschool↗
PubMed1988

Incidence of IDDM in Montreal by ethnic group and by social class and comparisons with ethnic groups living elsewhere.

We examined the incidence of insulin-dependent diabetes mellitus (IDDM) among children aged 0-14 yr in Montreal by social class and by ethnic group from 1971 to 1985. There was a slightly higher risk in wealthier as opposed to poorer classes. This income gradient was more marked in younger than in older children. Children of French extraction had about two-thirds the risk of IDDM of children of other origins, mainly British and other European. This mimics the patterns of risk in Europe, where France is reported to have lower rates than does Britain and Scandinavia. The absolute levels of risks among French Canadian and Jewish Canadian children were about double those reported from France and Israel, respectively. These various results are compatible with the hypothesis that both genetic and environmental factors influence IDDM risk.

Adolescent↗
PubMed1988

[Renal tumors in children, excluding Wilms' tumor. Apropos of 29 cases].

The authors present a multisource study of 29 kidneys tumors (Wilms excepted) in children. The most common types (18 cases) are tumors from metanephrogen blastema (congenital mesoblastic nephroma, nephroblastomatosis and nodular renal blastema, multilocular cystic nephromas. Mature kidney tumors are much more rare in childhood (8 cases): they are epithelial tumors (adenoma or adenocarcinoma) or mesenchymal neoplasms. In one case, histological study don't permit to list a malignant tumor to one of previous categories. Finely, among secondary tumors, two localisations of hemopathy are reported. After a limited exposure of cases and review of the literatures the authors emphasize the anatomo-clinical aspects, the value of paraclinical exams and the treatment of each type of tumor.

Female↗
PubMed1988

[Vesico-ureteral reflux. Ultrasonographic aspect of endoscopic treatment (excluding follow-up)].

Thirty four children, mean age 6 years, with reflux of 56 ureters were treated by an endoscopic approach. The technique, a recent innovation, attempts to reinforce the intravesical trajectory of the ureter by the injection of a Teflon disk below the vesical mucosa at the ureteral meatus level. The Teflon disk used is radiotransparent but could always be detected by ultrasound imaging, whatever its size, as a very reflecting image with a posterior cone shadow.

Administration, Intravesical↗
PubMed1988

[Fibrous epithelial polyps of the pyelo-ureteral junction in children. Presentation of 3 cases and review of the literature (33 cases)].

Primary ureteral tumors are rare and benign ones constitute only a small portion. Of the benign neoplasms, fibro epithelial polyps are probably the most common and could be considered to be an exceedingly rare cause of Hydronephrosis in children. The exact etiology of benign ureteral polyps is not certain but it is likely that they have a congenital one. They are mesodermal in origin and consist of a thick fibrous stalk covered by a layer of normal transitional epithelium. They are more commonly found in boys (80.6%), who present usually with abdominal pains or renal colics. Fibro-epithelial polyps often rise in the proximal ureter and renal pelvis, especially at the left side (69.4%). Radiographic signs are those of a non typical uretero-pelvic Junction obstruction. IVP and retrograde ureterogram usually demonstrate a long, thin, filiform, lucent filling defect within the ureteral lumen with moderate hydronephrosis. Appropriate treatment of these benign tumors is local excision with or without segmental resection. Prognosis should be considered as excellent without a report of recurrence. A review of the literature revealed 33 cases of ureteral polyps in children. We report here 3 additional cases of obstructing fibro epithelial polyps, observed in boys aged respectively 4, 8 and 9 years.

Child↗
PubMed1988

[Bladder immaturity in children: from enuresis to renal insufficiency].

The persistent infantile bladder is a common urological disorder in childhood. This syndrome is usually manifested by bedwetting, diurnal urge incontinence, characteristic holding postures, recurrent lower urinary tract infections and morphological changes of the bladder. The urodynamic evaluation show hyperreflexic bladder with detrusor sphincter dyssynergia. The pathologic mechanism is responsible for perpetuating and possibly initiating many "primary" vesico-ureteral refluxes. In most cases, the spontaneous resolution of detrusor activity by neurological maturation is usual. However, oxybutinin therapy (antimuscarinic drug) achieves pharmacological education of the bladder function and prevents complications due to high intravesical pressure induced by dyssynergia.

Acute Kidney Injury↗
PubMed1988

[The posterior approach in the treatment of hydronephrosis in children. Apropos of 65 cases].

The Simon posterior surgical approach to the kidney is excellent for pyeloplasty in children. The technique is reviewed and the advantages and limitation are discussed. This procedure has advantages of direct anatomic approach and excellent exposure of ureteropelvic area. In the newborn, the oral intake can be performed on the evening of surgery because there is no operative peritoneal mobilization. The posterior approach is especially recommended in simultaneous bilateral pyeloplasty. With transverse skin incision, a very cosmetic scar is obtained.

Child, Preschool↗
PubMed1988

[Aneurysmal bone cyst of C5. Complete 2-stage excision].

A case of aneurysmal bone cyst of the fifth cervical vertebra was unusual in that it occurred in a 35 year old man treated initially by radiotherapy (3,800 rads), within 3 years, worsening of clinical and radiologic signs led to a complete two-stage exeresis because of extension of lesion to body and posterior arch of C5. This male patient was 35 years old at diagnosis and 38 at time of surgery (respectively 1.2 and 2.5% of cases in the Hay series and 1.9% in the Ruiter series), this lesion affecting mainly age groups under 20 years. Aneurysmal bone cyst (ABC) constitutes 1.4% of primary bone tumors (Dahlin), and spinal localizations 3% (Biesecker), 14% (Reiter) or 20% (Tillman) of total ABC. The cervical lesion represents 13% (Reiter) or 22% (Hay) of spinal localizations, C5 being affected twice in the 17 cases reported by Ameli, and fills, according to Hay, 3.3% of all spinal column lesions and 15% of cervical lesions. Initial treatment applied in another center was by radiotherapy alone at the dose of 3,800 rads (the recommended dose-level in the literature being 20 to 30 Grays). Neither clinical nor radiologic improvement was reported. The recurrence rate after all types of treatment for ABC was 12.6%, and after radiotherapy alone was 11% in the Hay series, MacCarty reporting only one recurrence among 9 patients treated with irradiation alone.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1988

[Anuria in an infant caused by an intrapyelic mycelial bezoar in a solitary kidney].

A 4 month-old premature infant having received prolonged intensive care for necrotizing enterocolitis and Pseudomonas infection, developed anuria with intrapyelic fungus ball developed in a congenital single kidney. Review of the literature found 19 similar cases and emphasized the difficulty of an early diagnosis and the usefulness of renal ultrasonography for its detection. Moreover the opportunity to treat premature neonates carrying candida albicans with IV amphotericin B and flucytosine before the occurrence of an uneasy treatable urological obstacle in discussed.

Amphotericin B↗
PubMed1987

Cytogenetics of Abelson virus-induced malignant lymphoma cell lines in the mouse.

Cytogenetic studies were performed on 11 established murine thymoma or peripheral lymphoma cell lines induced by a thymotropic Abelson virus. In eight cell lines a trisomy 5 was present, whereas, two cell lines had a normal karyotype like fresh tumor cells. In the last cell line a trisomy 11 resulting from a t(5;11) was observed. The origin of this nonrandom chromosome abnormality is briefly discussed.

Abelson murine leukemia virus↗
PubMed1987

[Aggressive fibrous dysplasia of the mandible. Resection of the lower portion of the mandible].

Report of a case of swelling monostotic fibrous dysplasia in the left part of the mandible in a girl 8 years old. Two rapid recurrences after total curettage require the sus periostal resection of the left part of the mandible, without bone graft. Total recovery with 6 years follow up, with good cosmetic and functional result because of bone regeneration and growth stimulation by orthesis.

Bone Diseases, Developmental↗
PubMed1987

[A neuropsychic form of acute pancreatitis in a child. Apropos of a case].

We report the case of an 11 year-old girl with idiopathic acute pancreatitis in whom initial clinical symptomatology was resumed in marked neuropsychic signs and atypical abdominal pain. In such unusual circumstances, measurement of amylase levels as well as abdominal echography are of value for the diagnosis.

Abdomen↗
PubMed1987

[The urorectal syndrome caused by abdomen-levator incoordination in children].

We have studied thirty four children (mean age 6.6 years) with severe functional constipation, associated or not with encopresis. In twenty three cases the defecography showed a persistent anorectal angle due to failure of puborectalis sling relaxation during defecation straining. Voiding disorders, unknown to parents, but demonstrated by obstructive uroflowmetry, are also seen in nineteen of these children. Therefore is definite a true urorectal outlet obstruction syndrome by spastic pelvic floor mechanism. The exact etiologic factor of these functional abnormalities remains undefined. All children were managed by biofeedback training. A satisfactory result (with six months follow up), has obtained in fourteen cases.

Adolescent↗