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Biomedical subjects

D Aderka

Publications and source records attributed to D Aderka.

124 records · Page 7Linked to original sources
PubMed1977

Myocardial infarction association with the Riley-Day syndrome.

The "sudden death" of a 23-year-old Ashkenazy Jew, suffering from "familial dysautonomia" was probably caused by an arrhythmia accompanying a myocardial infarction. Such a report is unique. Diffuse coronary atherosclerosis and direct myocardial "catecholamine cardiomyopathy" seem responsible for the myocardial damage. However, diversion of the endocardial blood flow toward dpicardium and a "coronary steal" phenomenon, both the result of a sudden catecholamine discharge, could aggravate the ischemic injury.

Adult↗
PubMedDate not supplied

Absence of interferon activity during acute attacks of familial Mediterranean fever.

The pharmacokinetics of interferon, the symptoms caused by its administration, the decreased prevalence of viral diseases in FMF patients and the fact that colchicine, the drug of choice in the prevention of FMF attacks is an interferon antagonist, raised the question whether interferon may have a role in the pathogenesis of FMF attacks. An interferon activity was not detected in sera obtained at the height of FMF attacks in 8 patients, six of them under colchicine treatment. It is possible that the interferon activity has to be searched at the very beginning of FMF attacks, since at their height it already disappeared from the serum, while the symptoms of the attack are further mediated by other interferon-induced lymphokines.

Acute Disease↗