Pancreas transplantation: curative therapeutic approach to diabetic microangiopathy?
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Biomedical subjects
Publications and source records attributed to D Abendroth.
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Catheter embolization of renal arteriovenous fistulas is an effective alternative treatment to surgery; general anaesthesia is not necessary and the hospitalization is limited to 2-3 days. Suitable catheters, permanent occlusion material, such as butylcyanoacrylate, and balloon occlusion technique provide a safe and successful embolization even in cases with massive arteriovenous malformations.
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Twenty-one femoro-crural bypass procedures with a distal arteriovenous fistula (dAVF) were constructed in 20 patients with severe leg ischemia (Fontaine stage III, IV). They were followed-up for 3 to 22 months, with a mean of 8 months. The 15 patients with patent grafts and fistulas no longer had pain at rest; ischemic necroses healed. Telethermography showed a considerable augmentation of the distal limb perfusion. The mean increase of the transcutaneous oxygen pressure was 30 mmHg. One early postoperative amputation was necessary due to graft infection. Another patient lost her leg because of bypass occlusion 9 months after arterial reconstruction. Four patients with late graft occlusion kept their regained mobility and alleviation. Our data confirm experimental results suggesting that femoro-crural bypass with a dAVF improves distal leg perfusion by reversal venous blood flow and stimulation of a collateral network. Femoro-crural bypass with a dAVF may be of benefit in selected cases when only one crural artery is patent and pedal arch vessels are absent.
The neurovascular compression syndromes of the thoracic outlet are mainly characterised by pressure lesion of the brachial plexus and secondly in addition by vascular damages. An indication for surgery exists in cases of persistent or progressive complaints, loss of function of shoulder, arm or hand musculature as well as occurrence of vascular damage. The treatment of choice consists of transaxillary resection of the first rib. Irreversible vascular damage requires additional vascular surgery. Within 5 years 31 operations were performed in 27 patients with a thoracic outlet syndrome. Eleven patients became completely free of symptoms, nine showed clear-cut improvement. Four patients reported lack of improvement. Deterioration was seen in three patients. Preoperative atrophy of small hand muscles is associated with lack of complete functional restitution of nerves and muscles. Predominance of vascular symptoms permits complete restitution to be expected. Results in cases with predominantly neurological symptoms are unsatisfactory.
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