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Biomedical subjects

D A Edelman

Publications and source records attributed to D A Edelman.

136 records · Page 8Linked to original sources
PubMedDate not supplied

Current status of immunologic pregnancy tests.

Information about the mechanism of various pregnancy tests is summarized. The sensitivity of these tests as well as their advantages and limitations in a clinical setting are presented and evaluated in an effort to maximize their usefulness in a clinical setting.

Chorionic Gonadotropin↗
PubMedDate not supplied

A comparison of the Lippes Loop and two copper-bearing intrauterine devices.

A review of published studies and studies conducted through the International Fertility Research Program on the Lippes Loop D, TCu and Cu-7 shows that none of the three devices evaluated is better with respect to continuation and all types of event rates. There is a trend toward lower expulsion rates for the copper-bearing IUDs, but other factors such as the cost of devices and the need for replacement must be considered in determining the merits of the devices for large-scale programs.

Evaluation Studies as Topic↗
PubMedDate not supplied

Contraceptive development and testing in the United States of America.

Contraceptive development, including the development of IUDs, is discussed in light of the changing regulatory role of the FDA. The paper considers how the FDA and the government affect contraceptive development. Events that led to the demise of IUD use in the United States probably will have long-lasting effects on all future contraceptive development by the pharmaceutical industry in the United States.

Contraceptive Agents↗
PubMedDate not supplied

Diethylstilbestrol exposure and the risk of clear cell cervical and vaginal adenocarcinoma.

Data from two case-control studies that showed an association between in utero diethylstilbestrol (DES) exposure and clear cell vaginal cancer are evaluated. Neither study considered the cancer risk according to the reasons for prescribing DES and therefore cannot be used to infer any cause-and-effect relationship between DES exposure and vaginal cancer. Neither these studies nor any other studies have specifically evaluated the risk of clear cell cervical cancer to DES-exposed women. For DES-exposed women the risk of vaginal and cervical cancer is 0.5-2.0 cases per 1000 DES-exposed women; comparable data are not available for non-DES-exposed women.

Adenocarcinoma↗
PubMedDate not supplied

[Abortion or contraception (author's transl)].

The period immediately following an abortion, spontaneous or induced, has been considered favourable to the initiation of high efficicy contraception: sterilization, oral contraceptives, or intrauterine devices. The rate of post-abortal complications associated with these contraceptive methods was evaluated using data drawn from published and unpublished studies. The following conclusions were reached: sterilization is advisable only for women who do not desire additional children, and is obviously not recommended for young nulliparous women. The effective use of oral contraceptives requires a high motivational level and is therefore advisable only in cases where such motivation exists. The insertion of an intrauterine device seems to be the most adequate contraceptive method for women with low motivational level.

Abortion, Spontaneous↗
PubMedDate not supplied

Breast cancer risk among women using silicone gel breast implants.

Since their introduction in 1962, silicone gel-filled breast implants have been used by an estimated one to two million women. Questions concerning an increased cancer risk to these women have been raised. A review of the medical literature, including case reports, case series, physician surveys, case-control studies, and cohort studies, failed to turn up any evidence which associated the use of silicone breast implants with either an increased risk of breast cancer or an increased risk of a more advanced stage of cancer at the time of cancer diagnosis. The available data do not indicate any significant difference between the characteristics of the breast cancers of women with breast implants and those of women in control populations.

Adult↗