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Biomedical subjects

D A Edelman

Publications and source records attributed to D A Edelman.

At least 127 records · Page 7Linked to original sources

Oxytocin administration, instillation-to-abortion time, and morbidity associated with saline instillation.

Among 4,069 healthy gravidas undergoing saline abortion, patients administered intravenous oxytocin had a significantly shorter instillation-to-abortion time (median, 25.5 hours) than did patients not administered oxytocin (median 33.3 hours). The instillation-to-abortion time was independent of the rate of oxytocin administration, which ranged from 1 to 4 U. per hour (17 to 67 mU. per minute), but was associated with the time at which oxytocin infusion was begun. When oxytocin infusion was started within eight hours after instillation, a shortened time from instillation to abortion was observed. Although oxytocin augmentation may result in a lower proportion of patients being exposed to the risk of infection associated with prolonged intervals from instillation to abortion, this potential advantage appears counterbalanced by an increased incidence of clinical consumptive coagulopathy associated with instillation-to-abortion intervals of less than 24 hours.

Abortion, Induced↗

Menstrual regulation in the United States: a preliminary report.

The efficacy and safety of vacuum aspiration on an outpatient basis without anesthesia or cervical dilatation within 14 days of a missed menstrual period was evaluated in 1,009 women. Among those patients in whom pregnancy could be documented (54.8%), 4.2% were still pregnant after the procedure. Potentially serious complications were pelvic infection (0.4%), bleeding requiring a repeat curettage (0.3%), and prolonged bleeding (0.7%). For comfort, 26.7% received local anesthesia or analgesia. To allow selection of a higher proportion of pregnant patients, the probability of pregnancy was derived for patients with either a positive or negative pregnancy test at each length of amenorrhea. To determine the best vacuum pressure and source, and the cannula size and type at each duration of pregnancy, a more extensive (large, controlled, comparative) study is required.

Abortion, Induced↗

Outpatient laparoscopic sterilization with therapeutic abortion versus abortion alone.

Records of 108 patients undergoing combined vacuum aspiration and laparoscopic sterilization in an outpatient surgical program were reviewed and compared with those of 195 patients who underwent abortion only in the same outpatient program. Mean operating time for the combined procedure was 30 minutes; total mean hospitalization time was 5 hours and 7 minutes. Complication rates for the combined procedure and for abortion alone were 9.2 and 7.2 per cent, respectively. Subsequent hospitalization was necessary for 4.7 per cent of patients undergoing the combined procedure and 3.1 per cent of those having abortion only. Laparoscopic sterilization has been found to add no significant morbidity but has markedly reduced cost and hospitalization for the patient desiring permanent contraception following first trimester abortion.

Abortion, Therapeutic↗

Male sterilization in El Salvador: A preliminary report.

The expectation that male sterilization would not be an acceptable method of fertility control to the Latin American male has not been upheld in the initial phases of male sterilization programs in Colombia, Costa Rica, Guatemala, and El Salvador. On the contrary, in all of these programs and also at the Asociación Demográfica Salvadoreña, a free-standing, non-profit family planning clinic in San Salvador, the initial success has been impressive, with 180 men accepting sterilization during the first two years (February, 1972 to February, 1974). All sterilizations were performed by excising a 10-15 mm segment of each vas and ligating each vas end. Procedures were performed on an outpatient basis using a local anesthetic. Follow-up examinations were conducted at one week and three months after the procedure. Although complications were reported by 24.0% of the subjects at the one-week follow-up, the complications were minor: most were scrotal infections not requiring antibiotic therapy. Rates of complications were low for subjects returning for a three-month examination and semen test. Only one subject had a positive semen test.

Adult↗

Laparoscopic sterilization immediately after term delivery: a preliminary report.

To evaluate the feasibility and safety of performing laparoscopic sterilization immediately after a normal delivery, 46 patients were studied. All sterilizations were performed within 48 hours of delivery, using a single puncture technique with cautery and separation of the uterine tubes, under a neuroleptanalgesic. A description of the technique, the technical difficulties encountered in performing the procedures and the incidence of complications are presented. The technique, when performed during the early puerperium, is practicable since technical difficulties and the severity and incidence of complications are clinically acceptable. The sterilization procedure did not significantly increase the duration of hospitalization after delivery. Most patients were discharged from the hospital 1 to 2 days after the sterilization.

Adult↗

Early complications of sterilization in women not recently pregnant.

This study was conducted to evaluate the complications occurring during operation and from the time of operation until the follow-up vist at one to eight weeks after operation, for patients sterilized by culdoscopy, colpotomy, laparoscopy, or laparotomy. Surgeons were unable to perform the elected procedure in less than 1 per cent of the patients, independent of the method of approach. With endoscopic techniques, the most common operative difficulty was in obtaining an adequate view of the tubes. Excessive blood loss appeared more frequent with both vaginal techniques. Postoperatively, pelvic infections were more frequent with both the vaginal techniques, while incisional complications were more frequent with both the abdominal techniques. Operative and hospitalization times were significantly shorter, and the proportion of women resuming normal activities within four weeks of sterilization was higher with the endoscopic methods. Laparoscopy appeared to be the preferable procedure. While technical difficulties, operative complications, surgical and hospitalization times, and the time until the patient resumed normal work activities were similar with laparoscopy and culdoscopy; infection of the pelvis was more frequent after culdoscopy.

Adult↗