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Biomedical subjects

C Wood

Publications and source records attributed to C Wood.

At least 325 records · Page 18Linked to original sources
PubMed1986

Eosinophilic infiltration with flame figures. A distinctive tissue reaction seen in Wells' syndrome and other diseases.

We report five cases, all male, of diverse clinical findings of scattered erythematous, violaceous, or centrally blue plaques. Eight biopsies from the five patients showed nodular or diffuse dermal and subcutaneous infiltration, predominantly of eosinophils and histiocytes, with "flame figures" composed of granules of eosinophils that surround collagen bundles, whose staining quality is thereby altered. Two patients were children, the younger only 18 months old. Three patients initially presented clinical evidence of insect bites, and in one of these the biopsy showed cutaneous pseudolymphoma underlying dermal changes of eosinophilic cellulitis. Eosinophilic infiltration with flame figures is a distinctive reaction to various stimuli. It may be seen in a wide variety of clinical conditions and is not confined solely to patients with Wells' syndrome, which may be an acceptable term for clinically typical cases. Eosinophilic infiltration with flame figures is preferred descriptively to identify the microscopic changes in Wells' syndrome and in other cases like that of our patient with pseudolymphoma, in which the cutaneous reaction may be secondary to some other disease.

Adult↗
PubMed1986

Inflammatory granuloma annulare.

A case of inflammatory granuloma annulare occurring on the extremities of a young girl is presented. The lesions became erythematous and edematous concurrently with a self-limited gastrointestinal disorder. Many neutrophils were present in the biopsy specimen, which exhibited the changes of granuloma annulare.

Biopsy↗
PubMed1986

[Medical treatment of staphylococcal epiduritis].

The authors report a case of extensive spinal epidural staphylococcal abscess responsible for spinal compression. All symptoms regressed after conservative management consisting of parenteral antibiotic therapy with Gentamycin and Vancomycin.

Abscess↗
PubMed1985

Birth after transfer of cryopreserved embryos.

A normal baby girl was delivered after the successful transfer of two thawed embryos which had been frozen for eight weeks. Embryo cryopreservation may improve the chances of conception by women who are undergoing in-vitro fertilization (IVF), reduce the risks of multiple pregnancies in association with IVF, and offer the chance of conception to women with serious gynaecological disease which threatens ovarian function.

Adult↗
PubMed1985

The attitudes of the Australian community to treatment of infertility by in vitro fertilization and associated procedures.

Sequential surveys of public opinion within the Australian community have consistently demonstrated very significant support for in vitro fertilization (IVF) to enable infertile couples to have children. Embryo freezing and the use of donor gametes have lower approval rates, but those who approve significantly outnumber those who disapprove. There was no community concensus about the use of surrogacy as an extension of IVF treatment.

Australia↗
PubMed1985

A failed RCT to determine the best method of delivery for very low birth weight infants.

An RCT to determine the optimum method of delivery for very low birth weight (VLBW) infants was canceled after it had been in progress for only 5 months when it was discovered that more than 40% of eligible patients were being withdrawn from the trial before randomization. A review of hospital births before the trial began suggested that the trial was held too late: that a critical shift in obstetric practice towards abdominal delivery of VLBW infants had already occurred. Obtaining patient consent to participation, which had been the main predicted problem, was not difficult.

Cesarean Section↗
PubMed1985

Feasibility study: results of treatment of primary and recurrent adenocarcinoma of the corpus uteri with californium-252.

A trial of Cf-252 for the radiotherapy of primary or recurrent corpus adenocarcinoma was carried out at the University of Kentucky. The patients with primary tumors were of advanced age, poor general medical condition, and had multiple chronic medical illness, poorly differentiated tumors and/or metastatic Stage IVB disease. Fourteen patients with primary tumors were treated and all achieved complete local tumor control. The five year actuarial disease-free survival rate by the Kaplan-Meier method was 100% for Stage I-III disease, although 36% died of other, usually medical, causes. For eight patients treated with recurrent tumors, long term tumor control was 40% four year actuarial disease survival. Local control was 100% for vault recurrences of 3 cm diameter size, but only 6/8 (75%) cleared their pelvic tumors completely. Those that did not had tumors of massive size, distant metastatic disease and adenosquamous or poorly-differentiated (G3) pattern. One additional cut across, infected tumor was controlled for 26 months. Corpus carcinoma was highly sensitive to Cf-252 neutron radiation therapy.

Adenocarcinoma↗
PubMed1985

Factors influencing pregnancy rates following in vitro fertilization and embryo transfer.

In 831 patients having 1533 in vitro fertilization treatments, pregnancy rates were examined in relation to clinical and laboratory factors. Pregnancy rates were significantly affected by the month and year of treatment, the age of the patient, the type of ovarian stimulation, the use of human chorionic gonadotropin, the number of eggs collected, the number of eggs fertilized, the number of embryos developed, and the number of embryos transferred. The most important factors determining pregnancy rates were the number of oocytes collected and the number of embryos transferred. The low pregnancy rate when only one egg was collected raises the problem of how to predict and manage such a patient in a current or future treatment cycle.

Adult↗
PubMed1985

PUVA-induced melanocytic atypia: is it confined to PUVA lentigines?

Widespread lentigines in fourteen patients following long-term therapy with psoralens and ultraviolet A (PUVA) for psoriasis were documented by biopsy of a representative lesion in a non-sun-exposed site. Chronically PUVA-exposed nonlesional skin was examined in ten of the fourteen patients. Melanocytic atypia consisting of large or angular hyperchromatic nuclei was observed in 57% of PUVA lentigines and 70% of the nonlesional PUVA-exposed skin. Comparison with twenty-four specimens of lentigo simplex or solar lentigines revealed melanocytic nuclear atypia in only two cases. Binucleated melanocytes suggesting disturbed cellular kinetics were seen in all types of lesions examined but most commonly in PUVA lentigines. The presence of giant melanosomes was also a frequent nonspecific finding. Our findings of melanocytic atypia in chronically PUVA-exposed skin, as well as in PUVA lentigines, suggest that both sites are at risk for potential complications of repeated melanocytic stimulation. Whether melanocytic atypia will prove to be a precursor of melanocytic dysplasia or malignancy following PUVA therapy requires long-term evaluation.

Adult↗