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Biomedical subjects

C Werner

Publications and source records attributed to C Werner.

At least 253 records · Page 14Linked to original sources
PubMed1984

[Direct sonographic detection of tubal pregnancy following a fertilization operation].

In a case of fallopian pregnancy after a microsurgical performance for fertilisation we obtained the diagnosis by means of ultrasound. We saw the intact gestational sac and the embryo directly and point out the importance of early sonographical screening of pregnancy after surgical treatment of infertility. Diagnosis and differential diagnosis by ultrasound are discussed.

Fallopian Tube Diseases↗
PubMed1984

Bradycardia during severe but reversible hypovolemic shock in man.

Severe bleeding and hypovolemic shock causing hypotension are most often associated with tachycardia. In response to passive head-up tilt, five healthy men exhibited an increase in heart rate (HR) from 62 to 79 beats X min-1 and a gradual increase in the plasma concentration of aldosterone and protein. The increase in HR was followed by a decrease of 29 beats X min-1 (range 11-46) at the time when blood pressure decreased 38 mmHg (6-73). When tilted back to 0 degree, blood pressure immediately reversed while HR remained unchanged. Hypotension was associated with large but variable increases in plasma vasopressin (86 +/- 28 pg X ml-1) accompanied by peripheral vasoconstriction. In two cases where patients with internal bleeding presented with a moderate HR of 96 beats X min-1, the ensuing fall in blood pressure was associated with a decrease in HR to 68 and 76 beats X min-1, respectively. Administration of albumin solution and blood normalized cardiovascular function. Two other patients showing initial HR of 130 and 100 beats X min-1, respectively, also developed relative bradycardia in conjunction with a decrease in blood pressure. Administration of ephedrine and atropine increased HR temporarily from 56 to 90 and from 36 to 110 beats X min-1, respectively. The latter two patients died in extreme bradycardia and autopsies revealed severe internal bleeding. It is concluded that although hypovolemic shock is most often associated with an increase in HR, the increase is modest and a paradoxical bradycardia develops in severe but potentially reversible hypotensive hypovolemic shock.

Adult↗
PubMed1983

[Results of follow-up examinations after reduction mammoplasty].

164 patients in whom reduction mammoplasty according to Strömbeck had been performed, were followed up and questioned by means of a questionnaire as regards improvement of their preoperative complaints and their satisfaction with the success of the operation. 93% of the complaints were removed or at least alleviated. New complaints occurred in 16% of the women due to the visibility of the scars and scar pain. 51% of the women stated that the operation had been fully satisfactory, whereas 46% made some reservation and 3% were dissatisfied. The following complications were observed: 4 partial necroses of the mammillae, 2 haematomas, 2 wound infections, 2 fatty tissue necroses and 26 secondary sutures. The complications at the mammillae and the blood losses were found to correlate with the amount of resected weight. However, surgical experience was also an important factor, both as regards the complication rate and the cosmetic result, especially in cicatrisation and the shape and seat of the mammillae. On the whole, 69% of the results can be classified as "good", 30% as "satisfactory" and 1% as "poor".

Adolescent↗
PubMed1980

[A comparative study on early and late results following transcutaneous and intracutaneous suture in mediolateral episiotomy (author's transl)].

The techniques of postoperative treatment of mediolateral episiotomy by means of transcutaneous knotted suture and intracutaneous suture, are subjected to a comparative study. The non-resorptive suturing material Supramid of "O" gauge thickness was used in this study. There can be no doubt that patients' complaints following episiotomy were definitely less when using the intracutaneous suturing technique than with transcutaneous knotted sutures. After removal of the suturing material on the 6th. post-partial day there is a very definite reduction of complaints both with the knotted suture and the continuous intracutaneous suture. Late results 3 months post partum reveal a positive advantage of the intracutaneous suture with regard to the cosmetic aspect only. The advantages of intracutaneous suture compared with transcutaneous knotted suture following mediolateral episiotomy, therefore, are mainly represented by early relief of subjective complaints and improvement of objective pathological findings.

Episiotomy↗
PubMed1979

[Surgical procedure in exploratory incision of the mamma (author's transl)].

A comparison was made between two groups, each consisting of 50 women who had undergone an exploratory incision of the mamma because of suspected cancer at least one year and not more than two years previously. The women in group A underwent an operation in clinic A in which a radial incision was performed in the skin immediately above the tumor (GB: tumour). In contrast to this group B in clinic B had the tumor removed via parariola incision independent of the location of the tumor. In clinic A the incision was closed by subcuticular suture using individual button stitches on the surface. In clinic B subcutaneous stitching was not used; after thorough blood-staunching procedures the skin was closed with intracutaneous atraumatic techniques. Both groups were subsequently examined and post-operative complications and the complaints of the patients were registered. In addition the cosmetic result of the operation was taken into consideration. The examinations show that the parariola incision is the ideal technique for almost all exploratory operations of the breast. Although the post-operative phase is accompanied by a slightly higher incidence of haematomas these rarely require further corrective surgical procedures if blood-staunching is efficient and Redon drainage techniques are used. Between 1 and 2 years after surgery the parariola approach shows definite advantages when compared with radial incision directly over the tumor. The scars are almost invisible, definitely cause fewer problems for the patient, and rarely spoil the appearance of the breast.

Breast Neoplasms↗
PubMed1979

Prediction of lofepramine-response in depression based on response to partial sleep deprivation.

The improvement of depression after partial sleep deprivation in the second half of the night (sd) is tested for its predictory power for the therapeutical efficacy of pharmacotherapy with lofepramine. In a group of 15 patients with depression, we found that in contradiction to the findings of Wirz-Justice and collaborators (1976), the velocity of the antidepressive effect of sd has no predictive value. On the other hand, the amount of depression improvement after sd is of predictive value. This is independent of the time of occurrence of the improvement peak after sd. An improvement of more than 35% measured in the Bf-S or in the H.DRS on the first or the second day after sd is highly predictive for a good response to three weeks of 210 mg lofepramine per day (p = .05).

Clinical Trials as Topic↗
PubMed1978

[The influence of umbilical cord structure on the course of pregnancy and parturition (author's transl)].

A series of 549 not selected placentas and umbilical cords were examined to show the influence of the different development of the umbilical cord structure on the umbilical cord perfusion and the course of parturition. For this purpose the quantity of Wharton's jelly, the spiraling of the umbilical vessels as well as the length of the cord are defined. At the same time anatomical pecularities and complications like umbilical cord torsions and true knots are considered. To judge the decisive condition of the newborn and with that the course of parturition, the pH-value of umbilical artery blood is determined. The analysis results that umbilical cords with much Wharton's jelly and with spiraling vessels are converted into an association with extremely better value than those with little jelly and less spiraling vessels. Short and rich jellied umbilical cords show a significantly lower incidence of loops around the fetal body. A similar trend can be demonstrated for umbilical cords with strong spiraling arteries. Rare phenomena like velamentous insertion, haematomas, edemas and true knots of the cords etc. proved to have no influence on the course of parturition in our relatively small examination series.

Female↗
PubMed1978

Humoral and cellular immunity against allogeneic antigens in patients with acute leukaemia.

The humoral and cellular immunity of 12 patients with acute leukaemia (6 AML and 6 ALL) was investigated using several techniques. The study of the humoral response included the screening for allogeneic and autologous lymphocytotoxins, for cytotoxic antibodies against leukaemic blasts, Daudi cells and B lymphocytes and the detection of immune complexes. The cellular immunity was investigated by stimulation of remission lymphocytes by autologous blast cells or allogeneic lymphocytes in mixed cell cultures. Most patients have retained their humoral and cellular immune responsiveness against allogeneic antigens while there seems to be no significant response against leukaemia-associated antigens.

Acute Disease↗
PubMed1977

[Vulvar neoplasms and preoperative lymphography].

20 patients with histologically verified carcinoma of the vulva fulfilled the following conditions: general operability, preoperative lymphography, radical vulvectomy with inguinal lymph node resection and histological examination of all lymph nodes. It was studied how far the preoperative lymphography plays a role for the strategy of operative treatment of carcinoma of the vulva and eventually in the limitation of risks of operative treatment. A survey of the lymphatic drainage of the vulva underlines the importance of the knowledge of the lymphatic pathways for the operation and for the lymphography as performed in this hospital since 1972. The results suggest that lymphography shows an unacceptable high number of false-negative results in cases of metastatic involvement of the inguinal nodes (7 out of 10 cases), whereas it is reliable for the judgment of the iliac and paraaortal nodes. For this reason the resection of the inguinal nodes remains a necessary part of radical vulvectomy. The additional removal of intrapelvic lymph nodes has been restricted to patients with lymphographic signs of positive nodes. In our opinion preoperative lymphography is of considerable value to minimize the operative risk for patients with carcinoma of the vulva by means of a more precise preoperative diagnosis, stage-oriented therapy and postoperative control.

Aged↗