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Biomedical subjects

C Weller

Publications and source records attributed to C Weller.

60 records · Page 4Linked to original sources

Jet injection of insulin vs the syringe-and-needle method.

A new technique of injecting insulin without a needle employs a jet injector to administer a high-pressure stream of medication. This method causes very little pain and affords great accuracy, ease of administration, and safety. The medication is more widely diffused in the body by jet injection than by the needle-and-syringe technique. The control of blood sugar (with similar doses of insulin) achieved by the two techniques is similar, and their effect on local tissues is also similar. In the patients studied, jet injection appeared to be a very satisfactory method of administering insulin and has met with good patient-acceptance. Jet injection is also a useful method for the visually handicapped.

Absorption↗

Monitoring evoked potentials during surgery to assess the level of anaesthesia.

The hypnotic and analgesic components of anaesthesia can be assessed using middle latency auditory evoked potentials (MLAEPs) and somatosensory evoked potentials (SEPs). To monitor these potentials reliably during clinical anaesthesia, we have developed an evoked potential (EP) system based around a portable personal computer, a DSP board and an isolated pre-amplifier unit. Unlike many currently available systems, this amplifier is largely immune to diathermy interference due to excellent isolation via a digital fibre optical link, small size and RF screening and filtering. The pre-amplifier unit has integral auditory and somatosensory stimulators, and automatic calibration and impedance checking. Stimulus intensity and profile are under software control and SEP stimulus level is constantly monitored. The unit is powered by two AA cells and battery status continuously monitored by the PC software. Up to eight channels of EEG may be recorded and displayed in a smoothly scrolling window and as moving average MLAEPs and SEPs.

Anesthesia↗