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Biomedical subjects

C Weller

Publications and source records attributed to C Weller.

At least 55 records · Page 3Linked to original sources

"Free choice" as a restraint of trade, and the counterintuitive contours of competition.

This article explores the important implications of the little-noticed 1979 Federal Trade Commission ruling that the American Medical Association's ethics requiring "free choice" of physician violate the nation's antitrust laws. "Free choice" as it was known to the health care community for decades suddenly was illegal. To examine this counterintuitive aspect of competition, the article begins by defining two types of free choice. The AMA's free choice ethics, ruled inconsistent with antitrust law, is termed "guild free choice." The other, consistent with antitrust principles, is termed "market free choice." The distinction between market free choice and guild free choice provides a simple yet powerful tool for understanding many of the novel issues raised by the fundamental restructuring of the health care industry currently under way in the United States. For example, market free choice, deduced from the FTC ruling and the antitrust laws, is shown to be equivalent to proposals by Ellwood, McClure, and Enthoven for market reform. A history of American health care delivery and insurance from a free choice perspective reveals three historic periods: a market free choice era from 1870 to 1932, a guild free choice era from 1933 to 1982, and an emerging market free choice era today. Finally, the distinction is seen to undermine the conventional wisdom held by many physicians, economics and health care policy analysis.

American Medical Association↗

Thermal environmental monitoring of divers using a twelve channel multiplexing instrument.

A 12-channel temperature monitoring instrument designed for use by divers while immersed or within pressure chambers is described. Data are multiplexed at the diver and transmitted to the surface, bell, submarine, or chamber exterior through a two-core electrical cable. In the case of the immersed diver the cable may be incorporated into the diver's umbilical cable. Details of the method and special construction techniques used in the design of the diver-borne multiplexer are given. At the dive control station the 12 individual temperatures may be displayed in either digital or analogue format. The temperature data may also be stored on one track of a battery-powered magnetic tape recorder for subsequent off-line analysis.

Body Temperature↗

Monitoring of the neonatal electroencephalogram using an infrared multichannel telemetry system.

A 3-channel neonatal medical monitoring system is described which uses infrared light instead of electrical leads to transmit physiological signals from the neonate to monitoring equipment. This system is especially applicable to situations where low level physiological signals such as the EEG need to be monitored in the vicinity of other life support and monitoring equipment that is likely to introduce electrical interference. Examples of EEG activity showing the progress of a neonate, who had experienced asphyxia, are presented.

Asphyxia Neonatorum↗

Fetal electroencephalography using a new, flexible electrode.

A single flexible active electrode for monitoring the fetal electroencephalogram (FEEG), has been designed specifically for use in routine obstetrics. It does not require penetration of or adherence to the fetal scalp, and it is reusable. The equipment's performance has been tested in 20 normal labours. The recordings obtained were not contaminated by the fetal electrocardiogram and were relatively free from artefact so that minimal filtering of the signal was required. No FEEG signal was obtained if the electrode was applied to breech presentations. The trace obtained from a healthy fetus was comparable with that recorded after delivery.

Electrodes↗

A portable pulse-interval modulation telemetry/multiplexing EEG recording system for use in the home.

A portable 6-channel recording system employing time-division multiplexing with cable or radio-telemetry has been developed. The system is very compact and has proved to be reliable when used in a domestic environment. The use of multiplexing, in general, permits an expansion in the number of available channels and a reduction in equipment and tape costs, while the use of pulse interval modulation, in particular, overcomes tape recording limitations which may be encountered with the more common amplitude modulation techniques.

Electroencephalography↗

Prostatic secretion leukocyte studies in non-bacterial prostatitis (prostatosis).

Non-bacterial prostatitis is a common affliction among men and lacks objective criteria for clear identification. We studied 43 consecutive patients and 20 normal controls for the presence of bacteria and quantitation of prostatic secretion leukocytes. Significantly greater numbers of macrophages per volume of prostatic secretion were found in the patients. Multiple observations of such increased leukocyte proliferation could be used to establish true prostatic inflammation.

Adolescent↗

Characterisation of protein synthesis in cell-free extracts from different mammalian cells by their sensitivity to inhibitors of polypeptide-chain initiation.

Plasma cells and reticulocytes are differentiated mammalian cell systems specialized in the synthesis of distinct proteins. To study whether a cell specificity of polypeptide-chain initiation in such cell systems can be detected through inhibitors, the sensitivity to several drugs interfering with initiation was compared in cell-free systems with S-30 extracts from these cells. The following was indicated by the experiments: (1) under the selected conditions, the different cell-free systems are comparable with respect to their activity of initiation, and that aurintricarboxylic acid inhibits mRNA binding to the ribosome in plasma cell tumours the same as in reticulocytes. (2) The sensitivity of translation of endogenous mRNAs in reticulocytes and plasma cell tumours to inhibitors of mRNA binding to the ribosome, aurintricarboxylic acid and the homopolynucleotides poly(U) and poly(A), are different. (3) Inhibition of the succeeding reactions of peptide-chain initiation by sodium fluoride and pactamycin was not selective. (4) In both cell systems translation of poly(U) is equally sensitive to aurintricarboxylic acid. (5) In extracts from TEPC 15 myeloma cells synthesis of immunoglobulin L-chains compared with that of the other myeloma proteins is partially resistant to aurintricarboxylic acid, whereas in reticulocytes, no differential sensitivities of individual proteins could be observed. The different susceptibility of the mRNA binding reaction in plasma cell tumours and reticulocytes suggests that the predominant mRNAs of these cells have different affinities to ribosome binding sites.

Animals↗

Home health care.

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Cost-Benefit Analysis↗