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Biomedical subjects

C T Su

Publications and source records attributed to C T Su.

At least 91 records · Page 5Linked to original sources

Right ventricular ejection fraction. Validation of first-pass radionuclide studies by contrast angiography.

The accuracy of first-pass radionuclide angiocardiography (FPRNA) in the assessment of right ventricular ejection fraction (RVEF) using a multicrystal scintillation camera in the right anterior oblique view has not been reported. To test the validity of this technique, RVEFs derived from first-pass time-activity curves with and without background correction were compared with those obtained from contrast ventriculography in 36 patients. Background regions-of-interest tested included tricuspid valve, free wall, and horseshoe-shaped approaches. The tricuspid valve approach yielded a mean RVEF of 0.485 +/- 0.100 (SD) which slightly underestimated the contrast mean value (0.553 +/- 0.099, p less than 0.05) but correlated well (r = 0.88). The horseshoe approach yielded a mean value of 0.548 +/- 0.100 which approximated the contrast mean value and also correlated well (r = 0.81). The free wall approach yielded a mean of 0.502 +/- 0.095 which did not differ from contrast data (p greater than 0.05) but correlated less well (r = 0.77). With the method without background correction, a much lower mean value (0.387 +/- 0.081, p less than 0.01) and less correlation (r = 0.77) were obtained. Thus, FPRNA using a multicrystal camera in the right anterior oblique view is a reliable technique for measuring RVEF when a tricuspid valve or horseshoe-shaped background approach is employed, but is less accurate if the time-activity curve without background correction is applied.

Adolescent↗

Skin-flap metabolism in rats: oxygen consumption and lactate production.

Overall glucose metabolism was evaluated by measuring the rate of oxygen consumption (QO2) and lactate production in the pedicle skin flaps of rats. Skin flaps exhibited increases in QO2 and lactate production in vitro. The distal portion of the flap is characterized by a greater deposition of glucose to lactate during the initial 3 days following flap elevation. The contribution of glycolysis and of the oxidative pathways to glucose metabolism in skin flaps approximates that in normal skin on day 7 postoperatively.

Animals↗

Sagittal fractures of the maxilla and palate.

Sagittal fractures of the maxilla and palate are infrequent and can demonstrate significant instability with conventional methods of treatment. They require that rigid, horizontal stability of the dentition be obtained, as well as restoration of midface projection and height. The most effective and precise management has utilized a combination of open reduction and internal fixation at the piriform aperture and zygomatic buttress and posterior palate, use of a maxillary arch bar as a tension band, and utilization of a palatal splint.

Fracture Fixation, Internal↗

Tissue glucose and lactate following vascular occlusion in island skin flaps.

Neurovascular island skin flaps were elevated in the right groin area of Sprague-Dawley female rats weighing from 200 to 250 gm. Survival rates of the flaps were determined following venous and/or arterial occlusions of the femoral vessels. All the flaps exhibited an 80 percent decrease in tissue glucose content and an increase in tissue lactate content 4 to 7 times normal during venous and/or arterial occlusion. In the groups occluded for 8 hours, venous occlusion resulted in loss of all the flaps; arterial occlusion yielded survival of 70 percent of the flaps; and occlusion of both vessels yielded survival of 30 percent of the flaps. The results indicate that venous occlusion is more detrimental to flap survival than arterial occlusion. Surviving flaps exhibited a glucose content of 3.5 times normal, and dying flaps exhibited a glucose content of 20 percent of normal and a lactate content of 5.1 times normal. The ratio of tissue lactate to glucose may serve as an index for tissue viability: normal flaps, 0.3, surviving flaps, 1.2, and dying flaps, 7.5.

Animals↗

Electrical burns of the oral commissure: treatment results and principles of reconstruction.

Reconstruction of the average oral commissure electrical burn deformity yields good results when performed as a delayed procedure. Our preferred technique utilizes available vermilion for reconstruction of the lower lip by a rotation flap, and a mucosal advancement flap for reconstruction of the upper lip. Since using this procedure, we have not had a recurrent contracture requiring reoperation.

Burns, Electric↗

Adjunctive use of intravenous fluorescein in the tangential excision of burns of the hand.

The use of fluorescein as an aid to the differentiation of viable from nonviable tissue facilitates early tangential excision of hand burns. This technique, applied as part of an overall treatment program that includes immediate autografting with unexpanded meshed grafts and early mobilization, has resulted in excellent functional recovery from a potentially devastating injury.

Adolescent↗