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Biomedical subjects

C Stewart

Publications and source records attributed to C Stewart.

At least 217 records · Page 12Linked to original sources

Pregnancy-associated disease of the renal microcirculation.

1. Platelet factor 3, platelet survival, renal platelet localization and fibrinolytic activity have been studied in normotensive subjects with a previous history of pregnancy-associated hypertension. Studies were carried out up to 6 years after the complicated pregnancy. 2. Renal platelet localization was found to be significantly increased despite normal platelet survival and platelet factor 3 availability. Significant impairment of both resting and post-venous-occlusion fibrinolytic activity was also demonstrable. 3. The significance of these findings in relation to mediation of progressive intrarenal vascular disease is discussed.

Adult↗

Unilateral asterixis: motor integrative dysfunction in focal vascular disease.

In three patients we found unilateral asterixis in limbs contralateral to a discrete lesion adjacent to the internal capsule. Etiology was vascular in each, with no metabolic or toxic disturbance. Unilateral asterixis bespeaks focal disease arising from lesions in the thalamus or internal capsule and is a sign of motor integrative dysfunction.

Adult↗

Traditional religious orthodoxy, respect for authority and nonconformity in adolescence.

Broad generalizations regarding youth cultures must take into account the relative impact of conventional beliefs on adolescent behavior. Data obtained from 4,220 boys and girls from grades 8-12, in communities of different socioeconomic status, show that traditional religious orthodoxy and respect for authority represent viable social forces. The general assumption of a drastic decline with age in the commitment to these conventional orientations during adolescence requires some qualification. Beliefs dealing with respect for authority which lack specificity in regard to the institutional lucos of authority remain substantially unchanged with increasing age. Several traditional religious orthodox and respect for authority items either did not show a consistent decline with increasing age or showed only a slight decline. Commitment to these conventional beliefs is inversely associated with nonconforming behavior.

Adolescent↗

Spleno-hepatic tuberculosis due to Mycobacterium kansasii.

A case of tuberculosis of the spleen and liver is described. The organism involved was Mycobacterium kansasii, one of the atypical mycobacteria. The lack of evidence in the literature of primary splenic or hepatic involvement by this organism suggests that it is rare. In this instance it complicated a case of myeloproliferative disease, megakaryocytic myelosis with extra-medullary haemopoiesis, and was not diagnosed until autopsy.

Autopsy↗

Unusual foreign bodies of the temporal bone.

Foreign bodies that result from traumatic injury may be the cause of many clinical symptoms. Chronic otitis externa is one of the many clinical symptoms following a traumatic perforation of a foreign body from the oral cavity penetrating the deep tissue of the neck and ultimately lodging in the external ear canal. We discuss two such uncommon cases.

Child, Preschool↗

Six-year follow-up after Helicobacter pylori eradication in peptic ulcer disease.

BACKGROUND: The longterm outlook after Helicobacter pylori (H. pylori) eradication in peptic ulcer disease is unclear. AIM: This study documents H. pylori recurrence, dyspeptic symptoms and anti-secretory therapy in peptic ulcer patients six years or more after H. pylori eradication. METHODS: Peptic ulcer patients with H. pylori eradication between 1990 and 1992 were included. Infection recurrence was diagnosed by 13-carbon urea breath test (UBT). Dyspeptic symptoms and anti-secretory therapy use were assessed by questionnaire. RESULTS: Sixty-one patients completed the study protocol. Mean follow-up after eradication was 6.1 years (range 4.8-8.3). Four patients had a positive UBT. H. pylori recurrence rate was 6.6% or 0.02% per patient per year. Forty-two patients (69%) had dyspeptic symptoms. Heartburn and belching were more common than pain (p<0.001). All four patients with H. pylori recurrence had symptoms compared with 38 of 57 H. pylori-negative patients (p>0.05). Ten of 61 patients (16.4%) were taking anti-secretory therapy and their dyspepsia scores were higher. CONCLUSIONS: Despite a low H. pylori recurrence rate, longterm dyspeptic symptoms were common in peptic ulcer patients after H. pylori eradication. The symptoms are mainly reflux in type and require anti-secretory therapy in only a minority of patients.

Anti-Ulcer Agents↗