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Biomedical subjects

C Song

Publications and source records attributed to C Song.

At least 163 records · Page 9Linked to original sources
PubMed1993

[An experimental study of ocular contusion in rabbits: the changes in electroretinography].

In rabbits, the amplitude of a-waves and b-waves in the ERG declined following ocular contusion; however, the oscillatory potentials did not change markedly. In the anisodine therapeutic group, the amplitude of a-waves recovered higher than did that in the control group at the 2nd and 4th week post-traumatic, while all a-waves recovered at the 6th week in both groups. The amplitude of b-waves was restored to normal in 72 hours for all eyes. Since the a-wave was sensitive to contusion, it monitored the severity of damage and objectively evaluated the therapeutic effect of treatment.

Animals↗
PubMed1993

Role of total body irradiation as based on the comparison of preparation regimens for allogeneic bone marrow transplantation for acute leukemia in first complete remission.

The role of total body irradiation (TBI) for allogeneic bone marrow transplantation (BMT) for acute leukemia in first complete remission was reevaluated in this study. From Japanese BMT Registry, data of 123 acute leukemia patients in first complete remission who underwent allogeneic bone marrow transplantation in 22 hospitals between 1988 and 1990 were available for the present comparative study of preparation regimens with or without total body irradiation. Two-year survivals were 77% and 51% in the TBI containing regimen group and in the non-TBI regimen group, respectively (p = 0.0010). Corresponding two-year relapse rates were 16% and 37%, respectively (p = 0.0197). Corresponding probabilities of developing interstitial pneumonitis were 21% and 24%, respectively (p = 0.8127). The analysis of causes of death indicated that non-TBI regimen increased the incidence of septicemia and lethal organ failures, such as liver, heart, lung and other multiple sites. It was emphasized that an additional role of total body irradiation was to disperse the treatment-related toxicity in allogeneic bone marrow transplantation for acute leukemia.

Acute Disease↗
PubMed1992

[Effect of oxytocin and cholecystokinin octapeptide (CCK-8) on electroacupuncture (EA) analgesia].

The effect of oxytocin (OT) and cholecystokinin octapeptide (CCK-8) on EA analgesia was studied in rats. The increase of 20.8-39.8% and 9.0-45.0% in pain threshold was observed respectively when ICV of CCK-8 or naloxone was combined with EA, these increases were lower than that in saline-EA group significantly, while the simultaneous ICV of OT and CCK-8 or OT and naloxone in combination with EA produced the increase of 76.2-116.6% and 41.8-104.5% in pain threshold separately. These results showed that only a small part in the role of OT enhancing EA analgesia was blocked by CCK-8 and naloxone. The data suggest that the role of OT in EA was not entirely dependent upon the endogenous opiate peptides.

Acupuncture Analgesia↗
PubMed1992

[An experimental study of ocular contusion and its hemodynamic changes].

The hemodynamic changes in rabbit eyes following contusion were studied with rheoophthalmography (ROG), in which the wave amplitudes were markedly reduced and then recovered in 3 weeks, while in the anisodine-I treated group they recovered in 2 weeks. Contusion of 3 joules disrupted the choroidal circulation and damaged the retina. Anisodine-I improved the vasomotor functions of the choroidal vessels and was effective in treatment of ocular contusion. ROG was a sensitive objective means of estimating the severity of ocular contusion and evaluating the therapeutic effects.

Animals↗
PubMed1992

Study of experimental hypoparathyroidism in rats. III. Fluidity changes in brain synaptolemma.

The changes of brain synaptolemma fluidity in experimental parathyroidectomized (PTX) rats were studied by using fluorescence polarization and differential scanning calorimetry (DSC) techniques. The results showed that microviscosity (eta) of the rat brain synaptolemma in the cerebral cortex, hippocampus, midbrain and striatum were decreased after a 2-month period of continuous hypocalcemia, and in the hippocampus and cerebral cortex it was decreased significantly as compared with control. These results suggest that the fluidity of the synaptolemma in the brains of hypocalcemic rats is increased. In addition, hypocalcemia also lowered the Tc of hippocampus synaptolemma lipid, which indicates that both fluidity and permeability had increased in these rats.

Animals↗
PubMed1992

[Effect of Asu-AVT on electroacupuncture (EA) analgesia].

The Asu-AVT (1,6-aminosuberic acid -8-arginine-vasotocin) in an analogue of 8-arginine-vasotocin (AVT) which is one of pineal hormones. The effect of Asu-AVT on the pain threshold and EA analgesia was studied in rats. An increase of 16.2-41.5% in pain threshold was observed within 70 min. after ivc of Asu-AVT (75ng), while the Asu-AVT injection in combination with EA produced a significant increase of 164.6-309.1% in pain threshold, which was much higher than that in the saline-EA group (p < 0.05-0.01). The effect of Atu-AVT is analogous to that of oxytocin and arginine-vasopressin. The data indicate ivc of ASu-AVT not only elevates the pain threshold, but also enhances the EA analgesia. These results suggest that the pineal hormone, AVT may play a role in the EA analgesia.

Acupuncture Analgesia↗
PubMed1991

Use of costal cartilage cantilever grafts in negroid rhinoplasties.

Dorsal augmentation and nasal tip refinement are important objectives in Negroid rhinoplasty. Use of a costal cartilage cantilever graft will achieve these objectives. We report on our experience in 19 patients. The technique offers an excellent solution to supplying the large amount of material often required to adequately augment the dorsum in these patients. The graft is also versatile enough to allow nasal tip refinement. There are additional aesthetic benefits as the cantilever causes a lengthening in the nasal columella, a reduction in the flare of the nostrils, and increases the columellar-labial angle. The procedure is relatively simple to perform. The problem of warping is minimized by symmetrical carving and the use of large grafts with a substantial cross-section.

Anthropometry↗
PubMed1991

Long-term follow-up of hypothalamic-pituitary function in patients with transsphenoidal pituitary herniation and midfacial anomalies.

OBJECTIVE: We wished to determine whether patients with transsphenoidal pituitary herniation were at risk of developing pituitary failure. DESIGN: We followed up hypothalamic-pituitary function annually in patients with midfacial anomalies and pituitary herniation. PATIENTS: Two patients who had transsphenoidal pituitary herniation and midfacial anomalies were included and the literature was reviewed. RESULTS: Both patients became gonadotrophin, TSH and growth hormone-deficient despite neurosurgical repair. CONCLUSION: We conclude that the early diagnosis and neurosurgical repair of transsphenoidal pituitary herniation may prevent central nervous system infection and rhinorrhoea. Surgical repair may not prevent pituitary failure as was evident in both of our cases. Periodic evaluation of the hypothalamic-pituitary axis is essential to determine whether early hormonal replacement therapy is necessary.

Adult↗
PubMed1991

[Clinical significance of Doppler sonography in the diagnosis of anterior ischemic optic neuropathy].

The authors measured the PK (peak frequency with Doppler sonography in 52 patients of anterior ischemic optic neuropathy AION), 16 patients of oculovascular disease (OVD), and 371 normal subjects. The age ranged from 21 to 62 years in the patients, and 10 to 83 years in the normals. The arterial segments examined were of the bilateral common carotid arteries (CCA) and internal carotid arteries (ICA), totalling 272 segments in the patients and 1,484 in the normals, with the findings that the rate of carotid stenosis in AION was higher than in OVD, and carotid stenosis was observed in 75% of CCA and 91% of ICA in patients under the age of 30 years, significantly higher than in elder age groups. This provides a basis for the definite diagnosis of AION in patients under 30 years old.

Adolescent↗
PubMed1991

[Clinical and experimental research of the treatment of chronic renal failure with shenshuaifang].

33 cases of chronic renal failure (CRF) patients were treated by coloclysis with Chinese medicine Shenshuaifang (SSF). The effective rate was 60.61%, the total effective rate was 87.88%. It showed significant difference in the total effective rate compared with the control group (P less than 0.05). Animal experiments showed SSF could slow down the rising of the blood Cr and BUN of the mice which suffered with CRF, and reduce their urine protein. Conclusion. SSF had good effect on lowering the blood Cr and BUN of the CRF patients, so it could delay the progress of CRF, and it's effect was better than the general medical conservative treatment.

Administration, Rectal↗
PubMed1990

[Involvement of oxytocin in spinal cord in acupuncture analgesia].

The influence of intrathecal injection of oxytocin (OT), anti-OT serum (AOTS) and naloxone on pain threshold and electroacupuncture (EA) analgesia in rats was investigated. The tail-flick induced by potassium iontophoresis was used to measure the pain threshold. The increase in pain threshold was observed within 70 min after OT injection (100 ng), and it was much more effective than that of the ACSF injection (P less than 0.001). The OT administration could enhance the EA analgesia. This effect was of dose-related. Although injection of AOTS did not affect the pain threshold, it diminished EA analgesia. Furthermore, injection of naloxone did not influence the action of OT on EA analgesia. Our results showed that OT in spinal cord plays an important role in the EA analgesia, and its effects is independent of endogenous opiate peptides.

Acupuncture Analgesia↗
PubMed1990

[Surgical treatment of extensive recurrent hemangioma involving the eyelid].

Seven (7) cases of extensive hemangioma involving the eyelid, some with history of previous therapies, such as cryocoagulation, sclerosing agent or conservative surgical procedure that failed or the angioma rapidly increased in size after treatment, were performed radical excision by the authors with satisfactory follow-ups of 1-5 years. It was pointed out that conservative procedures could not cure palpebral hemangioma that were extensive and deep-seated.

Adolescent↗
PubMed1989

Calorie restriction delays age-dependent loss in androgen responsiveness of the rat liver.

We have shown that restricted calorie intake retards age-associated loss in androgen responsiveness of the rat liver. Sustained androgen receptivity delays age-dependent decline in the synthesis of the androgen-inducible alpha 2u globulin and derepression of the androgen-repressible senescence marker protein (SMP-2). Quantitation of mRNAs for alpha 2u globulin and SMP-2 in the liver of animals of various ages maintained on either ad libitum or restricted diets revealed that, although the 27-month-old ad libitum-fed rat had only 5% as much alpha 2u mRNA as the 6-month-old rat, the mRNA level was as high as 45% in the 27-month-old food-restricted rat. Conversely, the 27-month-old food-restricted rat had a much reduced amount (45%) of SMP-2 mRNA compared to the age-matched control that was allowed unlimited access to food. Furthermore, we have correlated the effect of dietary restriction on age-dependent changes in specific gene expression with the hepatic level of the immunoreactive cytoplasmic androgen-binding (CAB) protein. We observed that senescence in the male causes a substantial decrease in the circulating level of testosterone. However, dietary restriction does not retard the rate of decline in the plasma level of the male hormone during aging. These results indicate that age-dependent changes in the expression of androgen-responsive genes (alpha 2u globulin and SMP-2) reflect changing androgen sensitivity and that food restriction may directly influence the androgen receptivity of the liver.

Aging↗