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Biomedical subjects

C Signorelli

Publications and source records attributed to C Signorelli.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Indications for caesarean section: results of a local study.

Records from 6820 deliveries of three year (1980, 1985 and 1988) were reviewed in order to collect informations on cesarean section trend and its indications in a public hospital of Milan, Italy. Data show the magnitude of the phenomenon in the wards considered and an evident increase of cesarean section proportion from 1980 (18.6%) to 1988 (26.9%). The frequencies of major indications has not changed much apart from dystocia which has decreased and previous cesarean section which has increased. A logistic regression model was performed to evaluate cesarean section risk factors. Distribution of cesarean section during the days of the week show higher (about 30%) cesarean section proportion Monday through Thursday compared with low proportion (20% or less) on Fridays and weekend-days; this suggesting a possible high proportion of pre-programmed cesarean section.

Adult↗
PubMedDate not supplied

[Problems of laundry hygiene].

As the bacteria found more frequently in hospital infections are the same found in the linen, it is speculated that hospital linens can contribute to the spread of nosocomial patologies. Nevertheless this consideration does not prove that linen constitutes a significant source for transmission of hospital infections, although some studies have strengthened this possibility. The hygienic problems of hospital linens washing have a great importance and in this contest the possibility of contagion throught infected sheets or overalls constitutes only a part of the question. The problem of the spreading of nosocomial infections has to be divided into (1) collection and arlage of the linens; and (2) their disinfection and washing. Collection and carriage need precautions to prevent the hospital staff and the patients from the direct contagion, while during the washing the infected, or potentially infected, linen are to be regarded as a potential risk, which can be avoided through a disinfection before the standard washing cycle. During the washing the processes of cleansing, the dilution and the effect of temperature could be sufficient to obtain the final results. The last consideration is linked to gestational aspects, that's to say the consumptions, the costs, the traditional organizing procedures and the alternative ones, such as the possibility of substituting disposable material to linens or to refer to central laundries placed outside the hospital building and independently operated.

Containment of Biohazards↗
PubMedDate not supplied

[Tetravalent anti-meningococcal vaccine: serologic and clinical evaluation].

Meningococcal disease is the only bacterial meningitis able to cause an epidemic and the mortality due to this disease is all but negligible; therefore the active immunization induced by a vaccine that includes a large portion of Neisseria meningitidis serogroups responsible for the immunization of subjects at risk. Tetravalent vaccine containing polysaccharides of the serogroups A, C, Y, W135 has given good results both for tolerability and immune response. Considering the epidemic situation in Italy, this vaccine could be an excellent strategy "to behead" possible epidemics and/or hyperendemics due to a known serogroups.

Adult↗
PubMedDate not supplied

[Proposal for changing the ministerial instructions for antirabies prophylaxis in the light of the experience of the Centro Antirabbico di Roma].

Records of clinical assistance and of post-exposure antirabies prophylaxis from 4820 outpatients who attended the Antirabies Center of Rome following animal bites in 1986 were analysed. We observed a high proportion of people submitted to active immunization (44% received at least one shot of HDCV vaccine) in spite of the fact that rabies is absent from Central Italy since many decades in both wild and domestic animals. These considerations suggest the opportunity of a major revision of the official recommendations for rabies prevention, and we feel that different policies should be adopted in rabies enzootic areas (such as Northern Italy) compared to those where the risk is only potential. Immunization should be avoided after bites by rodents; passive immunization should be added to the vaccine after bites by wild animals in enzootic areas, while bites by cats and dogs, even uncaptured, will not be necessarily followed by vaccination in non enzootic areas.

Adolescent↗