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Biomedical subjects

C Signorelli

Publications and source records attributed to C Signorelli.

At least 19 recordsLinked to original sources
PubMed1991

Prevalence survey of nosocomial infections in a paediatric hospital.

A prevalence survey of nosocomial and community infections in a children's hospital was carried out in the wards of the Bambino Gesù Hospital, Rome, Italy. The overall prevalence of hospital-acquired infection (HAI) was 5.1%, with higher rates in surgical units and among children aged 1 to 5 years. The proportion of community-acquired infections was 9.2%, with higher rates in the infectious disease and internal medicine units and among children aged 6 to 11 years. The most frequent type of HAI was respiratory tract infection, with only a small number of urinary tract infections.

Child↗
PubMed1991

Trend of caesarean section in Italy: an examination of national data 1980-1985.

An Italian nationwide presentation of data concerning the proportion of births by caesarean section (CS) for the period 1980-1985 is presented here. A constant increase in CS was noted, from 11.2% in 1980 to 15.8% in 1985. The increase was observed in all regions while higher rates were noted in northern and central Italy. CS rates are higher in older age groups, in pregnancies from 29th to 35th week of gestation for high and low birthweights and malpresentations. Ecological associations revealed that CS is positively related to economic development and negatively to perinatal and stillbirth rates.

Adult↗
PubMed1990

Airport malaria.

Explore the source record for details and available documents.

Aircraft↗
PubMed1987

[Studies on the possible association between severe neurological syndromes and compulsory vaccination in Milano].

From June 1978 throughout February 1979, 66 children with a mean age of 13 months were admitted to a pediatric intensive care unit in Naples (Santobono Hospital) after a rapid onset of coma or deep stupor of unknown ethiology. The "mystery disease" ("il male oscuro") as somebody in Naples has defined this syndrome, was suspected to be associated with tetanus and diphtheria immunization. Epidemiological investigations and an international symposium of experts agreed not to consider the cases due to immunization. Some of these deaths were related with with Respiratory Syncitial Virus (RSV), evidence which is favored by the poor sanitary situation, evident in many sections of Naples. Although an ad hoc Committee appointed by the Italian Ministry of Health excluded any correlation with immunization, the Ministry of Health invited some Italian groups to carry epidemiological retrospective studies in some Regions of the Country. To obtain comparable results a special protocol was prepared. Two retrospective case-control studies, performed in Genoa and Florence, did not show any association between immunization with anti-diphtheria-tetanus and even anti-poliomyelitis vaccine and severe neurological illness. A retrospective study, performed by us at the Institute of Hygiene of the University of Milan for the years 1983, 1984 and 1985, has included not only the 208 admittances to the only pediatric intensive care unit of Milan (S. Carlo Hospital) but also the other intensive care units of Milan where, sometimes, children are accepted, especially if they were previously admitted to the pediatric wards of the same hospitals.(ABSTRACT TRUNCATED AT 250 WORDS)

Central Nervous System Diseases↗
PubMed1987

[Anti-rabies prophylaxis. Experience of the Antirabies Service of Rome].

Clinical records from 4820 outpatients who required assistance after animal bites during 1986 at the "Antirabid Center" of Rome were collected and analysed. The study was carried out to investigate epidemiology of animal bites among our population and the proportion of people who received post-exposure antirabid prophylaxis. We noted a high proportion of people submitted to rabies immunization after animal bites (44% received at least one dose of HDCV vaccine), in spite of the fact that rabies is absent from Central Italy since many years in both wild and domestic animals (being present, on the contrary, in Northern Italy). These considerations suggest the opportunity of a substantial revision of the official Recommendations, and we feel that a differential policy should be adopted in rabies enzootic areas (Northern Italy) compared to those where risk is only potential.

Adolescent↗
PubMed1986

Osteoid osteomas of the spine.

Seven patients with spinal osteoid osteomas are reported and another 110 cases from the literature are reviewed. Among the patients spinal pain is the constant clinical complaint, while radicular pain and scoliosis are present in half of the patients. Whereas radiograms and tomograms of the spine are sometimes inadequate for diagnosis, bone scanning is positive in 100% of patients and is useful for directing spinal computed tomography at the exact level of the lesion. Complete removal of the tumoral nidus produces remission of pain in more than 95% of cases. The possibility of an erroneous diagnosis of a lumbar protruded disk and the necessity of a bone scan in young patients with spinal or radicular pain are emphasized.

Adolescent↗
PubMed1985

Cobalt-57 bleomycin scanning for lung cancer detection: a prospective study in thoracic surgery.

Patients displaying an abnormal chest X-ray, in some cases, cause a difficult diagnostic problem. A differential diagnosis between benign and malignant lesions is important to determine the choice of treatment i.e. whether or not to perform a thoracotomy. In a prospective study, we have examined the role of 57Co-bleomycin scanning for prethoracotomy assessment of 60 patients with a high clinical probability of lung cancer. For these patients, a sensitivity of 89%, a specificity of 84% and an accuracy of 88% were found. However, as a consequence of the six false-negative scans (two in-situ carcinomas and four stage I carcinomas), bleomycin scanning cannot be regarded as adequate for obviating thoracotomy in patients with a high clinical probability of lung cancer but a negative scan. Nevertheless, the technique is useful for the assessment of tumour size and for the detection of hilar, mediastinal and extra-thoracic metastases, with consequences for TNM staging. It has been found that the tumour dimension correlates well with the actual anatomo-pathologic size determined after surgical examination (r2 = 0.65 and p less than 0.01). Therefore, with an accuracy around 90% for the diagnosis of lung cancer, 57Co-bleomycin scanning offers a major tool for use in clinical investigation.

Adenocarcinoma↗