Sodium nitroprusside treatment of ECT-induced blood pressure elevations.
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Biomedical subjects
Publications and source records attributed to C Salzman.
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We compare the effects of chlordiazepoxide, oxazepam, and placebo on hostility, as both an inner motivational or potential state and verbal interpersonal behavior. This article reports the findings relevant to the latter dimension of hostility and integrates them with those findings, presented in an initial report, relevant to hostility as an inner motivational state. The verbal data again support the hypothesis that chlordiazepoxide-induced increases in verbal interpersonal hostility, following frustration, are greater than those associated with placebo. With regard to oxazepam, the verbal hostility data were consonant with the motivational data that suggested that oxazepam does not substantially disinhibit hostility but did not as consistently differentiate oxazepam and chlordiazepoxide at the level of overt hostile behavior.
The author discusses the right to receive ECT and describes voluntary and involuntary patients for whom the treatment seemed both ethical and humane. The right to refuse ECT must be respected in competent patients. However, problems arise when patients' decision-making ability is compromised by their illness. Informed consent questions include how much and what type of information patients should receive and how much those with disordered cognitive functioning can be expected to understand. The author believes that ECT should be fully voluntary whenever possible and that a court-appointed guardian should make such treatment decisions for incompetent patients.
In a research group setting, marijuana increased social-emotional interpersonal communication and decreased task-oriented behavior. Following a frustration stimulus, groups of marijuana smokers appeared nonintoxicated and showed improvement in consensus problem solving. Interpersonal behavior with marijuana may depend in part, on the presence or absence of demand characteristics for task performance. Creativity in group problem solving was not improved by marijuana.
In a preliminary survey, 484 alumni of the Massachusetts Mental Health Residency Training Program from 1912 to 1967 were surveyed. Approximately 80% were found to have devoted half or more of their professional time to the nonprivate practice of psychiatry for at least one year. These data suggest that a training program with strong academic traditions might produce a preponderance of publicity of oriented psychiatrists. Since previous surveys have indicated a greater proportion of psychiatric time spent in private practice, we suggest that future surveys of psychiatric manpower need to consider the orientation of residency training programs in order to accurately assess the need for future psychiatric manpower.
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The authors used several indices to assess the relationship between marijuana and hostility as both inner affect and verbal behavior in a small-group setting. Marijuana subjects reported a small but statistically significant decrease in hostile feelings after the introduction of a frustration stimulus. They also showed significantly less verbal hostility than placebo subjects both before and after introduction of a frustration stimulus. The authors note that research findings on marijuana and hostility are not consistent and suggest a multidetermined relationship based on dose, environment, nature of the frustration stimulus, and intraindividual factors.
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Forty male volunteers over the age of 60 took either a daily dose of diazepam (12 mg) or placebo for a two-week period. Differential responses to these compounds partially depended upon age and the initial symptom level. Diazepam produced sedative side effects, a modest antidepressant effect, and a reduction in memory. Placebo had an antianxiety effect in the relatively older subjects, and was associated with decreased fatique, improved memory and improved motor function. Considerable variability was observed in both drug and placebo responses among the elderly. A self-rating depression scale (D30R) was useful for assessing changes in affective states and in discriminating between the effects of active drug and placebo.
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A questionnaire was used to survey the methaqualone experiences of college student users, and psychological test data from these users and a control group of non-users were compared. On differential pattern found was that methaqualone users have experimented with a wider variety of psychoactive drugs than have non-users. However, the two groups were essentially indistinguishable on the psychological test variables assessed. A preliminary modal profile of the college student methaqualone abuser and abuse experience was generated.
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