Search PubMed⌕ Search

Biomedical subjects

C Salmon

Publications and source records attributed to C Salmon.

At least 163 records · Page 9Linked to original sources

[Erythrocyte phenotypes in Gabon. I. Hemotypologic data].

Blood group antigens were investigated among 400 gabonese individuals subdivided in 6 ethnic groups. The frequencies were calculated and compared to those reported by MOURANT and al. on geographically close African populations. Our data enter the limits already known for a few antigens of ABO, Lewis, Rhesus, Kell, Duffy, Kidd, MNSs, P and Lutheran systems. In addition, we have observed some rare phenotypes: 12 S--s U--, 1 Lu(a--b--), 2 I negative and 7 Sc: --1.

Blood Group Antigens↗

[The P system].

Explore the source record for details and available documents.

Animals↗

Tk polyagglutination produced in vitro by an endo-beta-galactosidase.

After treatment with the culture supernatant of Bacteroides fragilis or with an endo-beta-galactosidase from Escherichia freundii, the human red blood cells are Tk-activated, i.e. agglutinable by BS II lectin and their blood group I and i activities are reduced. These results suggest that B. fragilis produces an endo-beta-galactosidase activity and that the main antigenic determinant of Tk polyagglutinable red cells is a terminal N-acetyl-glucosamine residue.

Agglutination↗

Comparative automated assay of anti-P1 antibodies in acute hepatic distomiasis (fascioliasis) and in hydatidosis.

An automated assay of anti-P1 allohemagglutinins has been carried out on 133 P2 subjects: 13 with acute hepatic distomiasis (Fascioliasis), 20 with hydatidosis and 100 healthy blood donors. Anti-P1 were detected in 100% of the distomatid sera, in 50% of the hydatid and in 29% of the healthy individuals. When compared to a reference serum test (anti-P1 standard), their concentration was found to be weak in healthy subjects, moderate in hydatidosis and exceptionally increased in acute distomiasis (up to 5-6 times the standard anti-P1 level). The 2-mercaptoethanol treatment showed that even the increased distomatid anti-P1 sera were of an IgM nature. The respective origin, synthesis and strength of these allohemagglutinins are discussed and the advantages of using distomatid IgM anti-P1 as human sera test are emphasized.

Autoanalysis↗

HD50 assay evaluation of the antigen Fy3 depression in Fyx individuals.

HD50 assays for the antigens Fyb and Fy3 were performed in a large number of Fyx homozygous or heterozygous individuals. A full correlation was found in quantitative expression of Fyb and Fy3 favouring the hypothesis of a Fybw Fy3w gene complex in the Duffy blood group system.

Blood Group Antigens↗

Haemagglutination kinetics using a continuous-flow system.

An automated technique for measuring haemagglutination kinetics is described. Equipment used in this test is very simple and already present in most blood transfusion centres. This method may be used with advantage to differentiate homozygous and heterozygous subjects in Rhesus, MNSs, and Kell systems, and to study antigen variations, especially in genetic investigations.

Hemagglutination↗

Relationship between I and H antigens. II. Study of the H and I deficient phenotypes.

H and I substances are present in the plasma and the saliva. In the plasma there is no quantitative relationship between H and I substances, whereas in the saliva only non-secretors produce I substance [shown by anti-Is serum, (Sti.)]. The study of I and H substances in the plasma and the saliva of H and I deficient subjects gives a better understanding and enables the completion of the classification of these rare phenotypes. The results also allow the proposal of a synthetic scheme of Is and H substances in the saliva.

Agglutination↗

Expected and observed proportion of subjects excluded from paternity by blood phenotypes of a child and its mother in a sample of 171 families.

The proportion of exclusion for a given mother-child pair is the proportion of males excluded from the paternity of this child of a known mother and may be calculated given both the child's and mother's phenotypes and the population gene frequencies. Its expected value in the population is equal to the probability of exclusion, which expresses a laboratory's capability to exclude from paternity nonbiological fathers.In a sample of 171 families examined for 20 genetic systems at the National Blood Group Reference Laboratory, 25 exclusions of putative fathers were detected. The ranking by efficiency of the systems used in these exclusions fits the "expectation of their efficiency," and the average proportion of males excluded by the child's and mother's phenotypes is not different from the expected proportion. Additionally, the repetition of exclusions in an incompatible putative father-mother-child trio is not dependent on the overall proportion of males excluded by the mother and the child, but rather on some high values of the proportion of excluded men in some specific systems.Here, formulas and some factors modifying these parameters as well as a more efficient sequence of examinations to exclude paternity than has previously been used are given. Using this sequence, laboratories which carry out several analyses per day can work by levels of five examinations at a time, done in a particular order, to obtain a rather rapid exclusion of certain families.

Adult↗

[Lewis blood group activity in Fasciola hepatica].

Lewis blood group specificities are detected in the liver Fluke: Fasciola hepatica. Such specificities had never been reported in nature, other than in the human body. The investigation of this phenomenon might contribute to a better understanding of the mechanisms involved in parasite-host relationship.

Animals↗

[K-Lymphocyte cytotoxicity: role of human blood group ABO, rhesus and P alloantibodies].

Using human erythrocytes of known antigenic density, sensitized by ABO and Rhesus (D) alloantibodies, it is shown that K cell cytotoxicity mediated by peripheral blood lymphocytes is directly correlated with the number of IgG molecules specifically bound to the target cell surface. The lytic sensitivity of P1k but not P2 or p erythrocytes coated with anti-Tja (anti-P + P1 + Pk) antibodies, demonstrates that effector K cells are mainly triggered through the IgG ANTI-Pk component of such sera.

ABO Blood-Group System↗