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Biomedical subjects

C S Bailey

Publications and source records attributed to C S Bailey.

46 records · Page 3Linked to original sources

Cutaneous innervation of the thorax and abdomen of the dog.

The anatomy of the cutaneous nerves innervating the canine thorax and abdomen was investigated by gross dissection of 38 dogs. Additionally, the cutaneous areas innervated by the thoracic and abdominal cutaneous nerves were mapped in a 2nd group of 33 barbiturate-anesthetized male dogs, using electrophysiologic techniques. The skin of the thorax was innervated by dorsal cutaneous branches, lateral cutaneous branches, and ventral cutaneous branches of the spinal nerves. The dorsal cutaneous branches were branches of the dorsal primary branches of spinal nerves C6 and T2 through T11. The lateral cutaneous branches were branches of the ventral primary branches of spinal nerves T2 through T12. The ventral cutaneous branches were branches of the ventral primary branches of spinal nerves T2 through T10. The skin of the abdomen was innervated by dorsal and lateral cutaneous branches of spinal nerves T12 through L3 (and occasionally L4). The cutaneous areas of the dorsal cutaneous branches occupied the dorsal half of the scapular and thoracic regions and the dorsal 2/5 of the abdominal region. The cutaneous areas of the lateral cutaneous branches covered the major portion of the ventral half of the thorax and the ventral 3/5 of the abdomen. The cutaneous areas of the ventral cutaneous branches occupied the axilla and the ventral part of the thoracic wall.

Abdomen↗

Spinal nerve root origins of the cutaneous nerves arising from the canine brachial plexus.

The spinal nerve root origins of the cutaneous nerves arising from the brachial plexus were investigated in 10 babiturate-anesthetized dogs by stimulating dorsal roots C5 to T2 and recording from each cutaneous nerve. Upon completion of the experiment, the contributions of the spinal nerve ventral branches to the brachial plexus were verified by anatomic dissection. The brachial plexus was formed by the ventral branches of C6 to T2 in 8 dogs, C6 to T1 in 1 dog, and C5 to T1 in 1 dog. The cutaneous branch of brachiocephalicus nerve was formed primarily by contributions from the C6 dorsal root. The cranial lateral cutaneous brachial nerve, a branch of the axillary nerve, was formed predominantly from C6 to C7. The median nerve received contributions primarily from C7, C8, and T1, and the communicating branch from the musculocutaneous to the median nerve contained fibers primarily from C7 and C8. The medial and lateral branches of the superficial branch of the radial nerve arose from C6, C7, C8, and T1, with the medial branch generally arising 1 segment craniad to the lateral. The palmar and dorsal branches of the ulnar nerve arose predominately from C8 and T1, and the caudal cutaneous antebrachial nerve of the ulnar arose predominately from T1 and T2.

Action Potentials↗

Response of muscle spindle primary endings to static stretch in acute and chronic spinal cats.

To evaluate fusimotor activity, the response of muscle spindle primary endings to static stretch was recorded from group Ia fibers in 8 control cats and in 31 cats at 3, 6, 14, 30, and 60 days after lumbar spinal cord transection. The spindle responses and clinical status of each group were compared with those of the control group. At 3 days after transection, the cats were hypotonic and mildly hyperreflexic. Spindle responses were significantly depressed. By day 6, the cats were mildly hypertonic and significant spindle recovery had occurred, although the responses were still significantly depressed from control levels. Spindle responses, hypertonia, and hyperreflexia continued to increase to day 30. At this time, spindle responses remained significantly depressed, although the cats were markedly hypertonic and hyperreflexic. A significant change in spindle activity or clinical status did not occur from 30 to 60 days after transection.

Action Potentials↗

Electrophysiologic studies of cutaneous nerves of the thoracic limb of the dog.

The cutaneous innervation of the thoracic limb was investigated in 36 barbiturate-anesthetized dogs, using electrophysiologic techniques. The cutaneous area (CA) innervated by each cutaneous nerve was delineated in at least five dogs by stroking the hair in the area with a small watercolor brush while recording from the nerve. Mapping of adjacent CA revealed areas of considerable overlapping. The part of the CA of a given nerve supplied by only that nerve is referred to as its autonomous zone. Of all nerves arising from the brachial plexus, only the suprascapular, subscapular, lateral thoracic, thoracodorsal, and cranial and caudal pectoral nerves lacked cutaneous afferents. The dorsal cutaneous branch of C6 had a CA, but no grossly demonstrable dorsal cutaneous branches for C7 C8, or T1 were found. The cervical nerves had ventral cutaneous branches, but no lateral cutaneous branches. Thoracic nerves T2-T4 had dorsal, ventral, and lateral cutaneous branches. The cutaneous branches of the brachiocephalic, axillary, musculocutaneous, radial, median, and ulnar nerves all had CA which were overlapped by adjacent CA, thus their autonomous zones were much smaller than the cutaneous areas usually depicted for these nerves in anatomy and neurology textbooks.

Animals↗

Measurement of deep body temperature from the urine.

1. The relation between urine and rectal temperatures has been studied under a variety of conditions by using the Uritemp bottle, which measures deep body temperature from the urine. 2. This device gives a reliable measurement of deep body temperature and has advantages over both rectal and oral techniques for many clinical applications. 3. The development of a new and more reliable device, the Uritemp meter, is described. Urine is voided through a specially designed and disposable unit, equipped with either a standard mercury-in-glass thermometer or any one of a range of commercially available electronic thermometers. Provision is made to collect a urine sample simultaneously if required.

Adult↗

Cervical chemonucleolysis in the dog. A surgical technique.

Cervical chemonucleolysis performed surgically in 16 clinically normal 4 and 10 year old Beagle dogs was well tolerated. The dosage of chymopapain per intervertebral disc was 200 or 500 U. Disc space narrowing was radiographically visible by day 1. By gross and histologic examination, there was lysis of the nucleus pulposus (NP) and perinuclear annulus fibrosus (AF). No observable differences due to ages of the dogs or doses of the enzyme were seen.

Age Factors↗

Magnetic resonance imaging and computed tomography characteristics of intracranial intra-arachnoid cysts in 6 dogs.

Magnetic resonance imaging (MRI) and computed tomographic imaging (CT) characteristics of intracranial intra-arachnoid cysts in six dogs are described. Of the six dogs, three were less than one year of age and 4 were males. Five of the six dogs weighed less than 11 kg. Five cysts were located in the quadrigeminal cistern. On CT images, the intracranial intra-arachnoid cysts had sharply defined margins, contained fluid isodense to CSF and did not enhance following i.v. administration of contrast. On MRI images, the intracranial intra-arachnoid cysts were extra-axial, contained fluid isointense with CSF and did not enhance following i.v. contrast. While spinal arachnoid cysts of dogs have been reported in the literature, other than the six dogs contained in this report, intracranial intra-arachnoid cysts have not to our knowledge been described in animals. These six dogs have a similar age, sex, history, clinical signs, CT and MRI findings to those reported in people with intracranial intra-arachnoid cysts.

Age Factors↗

Clinical forms of acquired myasthenia gravis in dogs: 25 cases (1988-1995).

The purpose of this project was to investigate the clinical forms of acquired myasthenia gravis in dogs. The medical records from 25 dogs with seropositive acquired myasthenia gravis were reviewed, and the following data were recorded for each patient: signalment, history, clinical findings; results of IV edrophonium chloride administration, repetitive nerve stimulation, and presence or absence of muscle membrane staining by immunocytochemical methods; serum acetylcholine receptor antibody concentration; treatment; and outcome. Several clinical forms of acquired myasthenia gravis were identified. Nine of the 25 patients (36%) had no historical or clinical evidence of appendicular muscle weakness, and were designated as focal myasthenics. These dogs exhibited focal weakness in one or more of the following muscle groups: facial (3 of 9), pharyngeal (3 of 9), and laryngeal (3 of 9). The remaining 16 dogs (64%) exhibited appendicular muscle weakness. Four of these 16 dogs had acute onset and rapid development of clinical signs, and were designated as acute fulminating myasthenics. The remaining 12 dogs were classified as generalized myasthenics. All 4 dogs with acute fulminating myasthenia gravis had megaesophagus, 2 had facial muscle weakness, and 1 had pharyngeal muscle weakness. Ten of the 12 dogs with generalized myasthenia gravis had megaesophagus, 4 had facial muscle weakness, 4 had pharyngeal muscle weakness, and 3 had laryngeal muscle weakness. Historical or clinical evidence of exercise-associated appendicular weakness was found in only 6 of the 12 (50%) dogs with generalized myasthenia gravis, and in none of the dogs with acute fulminating myasthenia gravis. Seven of the 12 dogs with generalized myasthenia gravis had weakness primarily (n = 1) or exclusively (n = 6) of the pelvic limbs. Two of the 4 dogs with acute fulminating myasthenia gravis had primarily pelvic limb weakness. Twelve of the 25 dogs (48%) died or were euthanized shortly after admission to the hospital due to aspiration pneumonia. The dogs with acute fulminating myasthenia gravis had a markedly higher 1-year mortality rate in comparison with the other 2 groups. The use of immunosuppressive therapy had a significant positive effect on patient survival, regardless of the type of myasthenia gravis. This investigation demonstrates that acquired myasthenia gravis in dogs is a disorder with a wide spectrum of clinical forms, similar to the analogous disorder in people.

Animals↗

Spinal epidural empyema in two dogs.

Extensive, diffuse, epidural spinal cord compression was visualized myelographically in two dogs presented for rapid development of nonambulatory tetraparesis and paraplegia, respectively. Purulent fluid containing bacterial organisms was aspirated percutaneously under fluoroscopic guidance from the epidural space of each dog. One dog responded poorly to aggressive medical therapy, which included installation of an epidural lavage and drainage system. Both dogs were euthanized due to the severe nature of their disorder and the poor prognosis. Spinal epidural empyema (i.e., abscess) is a rare condition in humans and has not been reported previously in the veterinary literature. Spinal epidural empyema should be considered as a differential diagnosis in dogs presenting with painful myelopathies, especially when accompanied by fever.

Animals↗