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Biomedical subjects

C Rumeau-Rouquette

Publications and source records attributed to C Rumeau-Rouquette.

At least 37 records · Page 2Linked to original sources

[Registration of children's accidents in health care and prevention facilities of a health sector].

In 1981-82, 5, 963 children's accidents were reported over a one-year period in 2 public and 11 private hospitals in a given public health district. The nature of treated accidents in the public hospitals differs from that in the private facilities. Reporting of cases reaches 75% in the public hospitals; only about 50% in the private hospitals. Characteristics of reported accidents differ from those unreported. While the quality of clinical data is satisfactory, the site of the accident is unknown in 14%, and the causal agent, in 35% of the cases. The estimation of incidence implies the extension of registrations to the private sector, source of 31% of reported cases, and where significant differences from the public sector were observed in the nature of the accidents. A permanent system requires use of a rolling sample and training of personnel. Systematic registration is a tool to measure incidence of accidents, but is not a suitable instrument for the surveillance of dangerous products and objects.

Accidents↗

[Fetal hypotrophy. Statistical analysis of placental changes].

The purpose of this research was to study the relationship between placental characteristics and the degree of failure of growth between 37 and 41 weeks of pregnancy. The cases of severe small-for-dates (percentiles of 1 to 5) and moderate small-for-dates (percentiles of 6 to 10) were compared with a control series (percentiles of 11 to 90) with an equivalent gestational age. In both groups of small-for-dates babies one could find that the chorionic arteries and their trunks were of a lower diameter than those of the villi that were small and that there were sub- chorial deposits of fibrin in both groups. The greater number of placental abnormalities were found in those babies who were severely small-for-dates at a gestational age of between 37 and 39 weeks. The relationship between acute fetal distress and small for dates was analysed. There was little difference in the likelihood of fetal distress between the two groups of small-for-dates babies, but there were differences between both groups and the control group.

Female↗

[Evolution of the mortality rate of newborn infants transferred to a Parisian intensive care service from 1969 to 1978].

This study reports on the trend in neonatal death rates in a Paris intensive care unit between 1969 and 1978. Three time-periods were compared: 1969-1971, 1972-1974, and 1975-1978. These limits were chosen to take into account the introduction of continuous airway positive pressure in the unit in 1972, and the gradual implementation, from 1972 onwards, of a new perinatal care policy in France. The mortality rate was significantly lower in the second period than in the first, after adjustment on birthweight and type of disease. This trend varied according to type of disease: the death decreased significantly in case of membrane disease or foetal distress, but not in case of admission for amniotic inhalation or congenital anomalies. The gradual improvement in newborn's condition on arrival in the unit played a part in the improvement in survival, as well as the use of the continuous airway positive pressure.

Critical Care↗

Fetal growth retardation in gestational hypertension: relationships with blood pressure levels and the time of onset of hypertension.

To evaluate the effects of gestational hypertension on fetal growth, we studied the standardized records of 2996 single live-birth pregnancies. Mothers all had documented diastolic blood pressure of less than 85 mmHg before the 16th wk of amenorrhea and no history of pre-pregnancy hypertension or kidney disease. Diastolic blood pressure readings exceeding 84 mmHg were found later in pregnancy in 38.4% of the mothers, and were associated with an increased number of small-for gestational-age infants: 3.2% in mothers whose diastolic blood pressure had never reached 85 mmHg, 6.3% when peak diastolic blood pressure had been in the 85-94 mmHg range, and 8.5% when it had exceeded 94 mmHg (p less than 0.01). In mothers who had had one or more diastolic readings of more than 84 mmHg, and for all peak diastolic pressures, the rate of small-for-gestational-age infants was higher when hypertension had begun early in third trimester (between the 27th and 36th wk), than in the second trimester or later than the 35th wk (10.2% compared to 5.6 and 6.1% respectively, p = 0.02). This temporal reinforcement of the adverse fetal effects of hypertension when it began in the early third trimester was not explained by differences in the incidence of proteinuria or in maternal age, parity, obstetric history or smoking habits.

Adult↗

[Incidence and fetal impact of hypertension in pregnancy: study of 2996 pregnancies].

To evaluate the incidence and the foetal effects of gestational hypertension, we studied 2 996 pregnancies with a single live birth in mothers selected on the basis of 1) a documented diastolic blood pressure (DBP) less than 90 mmHg before the 16th week of amenorrhea and 2) no history of hypertension or kidney disease. In 38,4% of the gravidas, the highest DBP during pregnancy was greater than or equal to 90 mmHg, and in 15,4% this level was reached twice or more. Gestational hypertension (two DBP readings greater than or equal to 90 mmHg) was more frequent in nullipara than in mothers with previous pregnancies (17,9 versus 12,4%, p less than 0,01) and its incidence tended to decrease with increasing maternal age. Irrespective of parity or maternal age, a significant increase in the percentage of small for gestational age infants was associated with increasing DBP levels: 3,2, 6,4 and 8,5% when the highest recorded DBP was less than 90 mmHg, equal to 90 mmHg (even at one single reading), or greater than or equal to 100 mmHg respectively (p less than 0,001). Very similar percentages were obtained in non-proteinuric pregnancies: 3,3, 6,5 and 7,8 respectively (p less than 0.001). Non-proteinuric gestational hypertension, even mild or transitory, is indicative of a high risk pregnancy and requires close medical supervision.

Blood Pressure↗

[Transfer of neonates in northern france. Factors of mortality (author's transl)].

An extensive study was undertaken in northern France from January 1st to May 31st 1978, concerning the transfer of neonates from maternity hospitals to specialized units. Analysis of 250 children whose birth weight was below 2,000 gm showed that several risk factors could be taken into account to reduce neonatal mortality in this area. Prematurity (22% children weighing less than 1,500 gm in those discharged alive, 54% in the dead), neonatal distress (36% versus 61% of resuscitation) hypothermia (7% versus 23% with temperature below 34 degrees 6 at the time of admission), the need for an other transfer (1% vs. 12%) seem to be features highly related with poor prognosis. This stresses the importance of the prevention of prematurity, of proper management of the babies in the maternity hospital, of the conditions of transport and of the choice of the neonatal unit.

France↗

[Antenatal care and source of care during pregnancy (author's transl)].

The influence of the source of care on the unequalities in the number of antenatal visits was studied in a representative sample of births in France in 1976. The sources of care during pregnancy were divided into five groups according to number and qualification of the medical staff involved: hospital antenatal clinic, gynaecologist or obstetrician, general practitioner, hospital antenatal clinic and other practitioners, several practitioners outside hospital. The number of antenatal visits was related to the source of care. The inequalities in antenatal care according to maternal characteristics originated from inequal access to the most specialized sources of care and disparities in the number of visits within each source of care. Living in a big conurbation was a positive factor for consulting an obstetrician, going to hospital antenatal clinic and having a large number of visits; but even after allowing for this factor, there remained inequalities among women according to their socio-demographic characteristics or the source of care.

Adult↗

[Occupational activities of pregnant women, prenatal care and pregnancy outcome].

The study of a national sample of births showed that, in 1976, more than 50% of French women worked during pregnancy. Working during pregnancy was, on the whole, associated with better antenatal care, and better outcome of pregnancy. This relationship remained after taking into account the more favourable social characteristics of working women. Nonetheless, physically hard working conditions were associated with a high risk of preterm delivery.

Adult↗

Moderate alcohol use and pregnancy outcome.

Pregnancy outcome has been studied in relation to maternal alcohol consumption in two prospective surveys in public hospitals in Paris and one retrospective survey on a national sample. These studies have not shown any relationship between alcohol use during pregnancy and major congenital malformations. There was an excess of stillbirths, significant only in the first study, and a decrease in placental weight among women drinking more than 40 cl of wine or its equivalent in other alcoholic beverages per day. The national survey also showed a higher pre-term delivery rate. A decrease in birthweight was observed mainly for moderate or heavy beer drinker. These relationships remained after adjusting for confounding factors.

Abnormalities, Drug-Induced↗

[A study of the prognosis at one year after restorative tubal surgery in the treatment of sterility (author's transl)].

A cooperative study has been carried out on 301 women who were operated on for tubal sterility in 9 centres in different countries between 1969 and 1974. 19 per cent of these started an intra-uterine pregnancy and 4 per cent an extra-uterine pregnancy during the first year they were followed up. The results reaffirm the poor prognosis of genital tuberculosis, of tubal blocks found on hysterosalpingography and of adhesions discovered on laparoscopy. If the type of operation has little relationship to the results, these do change according to the treatment given around the time of operation. There were more intra-uterine pregnancies in women who had treatment systemically with corticoids and with antibiotics than in those who only had corticotherapy locally. This result has been confirmed when results have been compared taking into account the Centre where the operation was carried out and the type of lesions that were discovered on hysterosalpingography and on laparoscopy.

Adult↗

[Evolution of breast-feeding in France from 1972 to 1976 (author's transl)].

Two national surveys of representative samples were held in France in 1972 and 1976. They revealed an increase in the frequency of breast-feeding in the neonatal period (from 36.6 to 45.5%). This increase was observed in almost all regions and population subgroups. Breast-feeding remains influenced by ethnic group (more frequent in immigrants), social level, the quality of prevention and the size of maternity-hospitals. Classification of French women in 6 groups by education and care received (number of beds in the maternity-hospital) shows that the frequencies of breast-feeding range from 65% (university-educated women giving birth in large maternity-hospitals) to 28.5% (women with primary or secondary education, giving birth in small maternity-hospitals).

Breast Feeding↗

[Hormonal tests of pregnancy and congenital malformations (author's transl)].

I.N.S.E.R.M. has carried out two prospective inquiries centred on the evaluation of the teratogenic action of drugs on human beings. The first survey was between 1963 and 1969 and the second between 1975 and 1977 and they were carried out in maternity hospitals. The first test, which was carried out on 12,764 women, had shown no overall association between the use of hormonal tests for the diagnosis of pregnancy (oestrogens-progestogens) and congenital malformation in the infant. The second study, which was carried out on 3,451 women who were questioned in the same way, shows that there is an excessive number of newborn babies with malformations when the mothers took certain products (oestrogens-progestogens when the progestogen was a derivative of testosterone). The problem of a methodological bias is discussed and the results are interpreted in the light of epidemiological studies that have recently been carried out abroad.

Abnormalities, Drug-Induced↗

[Contraception and antenatal care (author's transl)].

Taking a representative sample selected from 11,220 deliveries the authors set out to study the interrelationship between contraception, antenatal care and socio-cultural factors. They show that there is a liaison between the first two variables even taking account of the socio-cultural factors which were found. This result leads to the conclusion that the spread of contraceptive information brings with it an improvement in the statistics for perinatal results.

Adult↗