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Biomedical subjects

C Ricour

Publications and source records attributed to C Ricour.

At least 181 records · Page 10Linked to original sources
PubMed1978

[The child in digestive resuscitation].

Twenty one children who had total parenteral nutrition followed by a constant infusion into the gastrointestinal tract between the 10th and 90th day of life were studied. When normal feeding is resumed the difficulties are related to the lengths of hospital stay, separation from the parents and the lack of contact with adults more than to the techniques of feeding themselves.

Child, Preschool↗
PubMed1978

[Enterocutaneous fistulas of the small intestine in children: therapeutic approach. Study of 22 cases].

25 cases of post-operative small intestinal fistulae in children are described. 24 benefited by intensive feeding either exclusively parenterally (20 cases) or orally by constant infusion of an elemental diet (4 cases). In 13 cases the fistulae closed spontaneously but the other 11 needed further operations after an average of 41 days feeding. 2 children died; 1 was operated on early and the other had chronic granulomatous disease. Thus it is important to avoid early surgical intervention and to ensure adequate drainage of fistulae. Intensive feeding either parenterally or orally has an important role in this condition.

Adolescent↗
PubMed1977

[Intrahepatic organic cystals in artificial feeding of children (author's transl)].

Crystals have been observed in the liver of 4 children, submitted to a parenteral nutrition and or, continuous enteral nutrition. Those crystals appear to be birefringent with polarized light extra and intracellular in electron microscopy, they contain a large amount of calcium, phosphore and sulfur. They are thought to represent organic crystals precipitating within the bile ductules of the portal areas. The occurence of those organic crystals seems to be related to a lack of bile secretion due to the exclusion of kinetic and secretory activity of the stomach and the duodenum.

Bile Ducts, Intrahepatic↗
PubMed1977

Intestinal calcium-binding protein 3 months after massive small bowel resection in the piglet.

Changes in intestinal calcium-binding protein and calcium binding activity were studied at resection and 3 months after 90% small bowel resection in piglets and one adult pig. A calcium-binding protein (MW congruent to 11.000) with calcium-dependent eletrophoretic mobility was partially purified from mucosal extract of proximal jejunum, mid-gut, and ileum. The concentration of calcium-binding protein and the calcium-binding activity of the intact animals were found highest in the proximal jejunal segment, lowest in the ileal segment. After resection in the four surviving animals out of nine, a significant increase in calcium-binding activity was observed in the proximal jejunum and in the distal ileal segment. The change in calcium-binding activity was much more marked in the ileum than the jejunum. These data demonstrate that pig intestinal mucosa possesses an adaptive capacity to increase the synthesis of calcium-binding protein after massive small bowel resection.

Adaptation, Physiological↗
PubMed1977

[Continuous enteral feeding in children. Technic and indications in 170 cases from 1969 to 1975].

170 children with severe undernutrition of whom 153 were babies, received continuous gastrointestinal infusion from a minimum of 3 weeks to a maximum of 18 months. Eighteen died as a result of the primary disease: results were considered very satisfactory in 148 children whilst 4 were still dependent on the technique 24 months later. In 65% of cases it was necessary to precede this intestinal infusion by intravenous feeding through a caval catheter. The authors discuss the choice of site of the infusion and the composition of the infusate according to the nature of the underlying intestinal disorder. The general and gastrointestinal indications both medical and surgical, are discussed in detail.

Adolescent↗
PubMed1977

[Obstinate diarrhea in infants. A review of 84 cases].

Eighty-four cases of obstinate severe diarrhoea in infants are reported. Criteria for clinical and biological severity are precised. Histological examination of the small bowel was performed in 57 cases; a total atrophy of intestinal villi was found in only 33% of the cases during the first 3 months. Exclusive parenteral feeding, from the beginning or after failure of enteral feeding was given to 71 infants. Later on, enteral renutrition at constant flow, was administered, after simple preparation, in most cases. Seventeen died out of 84 infants, 7 of them within 2 weeks. For the others, the average time for recovery was 4 months. The conditions of prevention of obstinate severe diarrhoea in infancy are emphasized.

Diarrhea, Infantile↗
PubMed1975

Radiation enteritis in children. A retrospective review, clinicopathologic correlation, and dietary management.

The clinicopathologic features of radiation enteritis are reviewed in 44 children receiving whole abdominal radiation therapy between 1961-1972 at the Institut Gustave-Roussy. Five of 14 long-term survivors (36%) developed severe delayed radiation injury with small bowel obstruction, occurring within 2 months after completion of irradiation. All had previously had acute radiation reaction during therapy. Histologic appearance in the small bowel at the time of delayed radiation injury revealed severe villus blunting, lymphatic dilatation, and moderately dense inflammatory infiltrate. All patients with delayed radiation injury showed marked clinical improvement coincident with a fractionated low-residue, low-fat diet, free of gluten and free of milk and milk products. The abnormal small bowel roentgenographs and small bowel biopsies reverted to a normal appearance in association with the diet. No exacerbation of radiation enteritis has been seen following dietary therapy.

Adolescent↗
PubMed1975

Cholelithiasis and ileal pathology in childhood.

Primary cholelithiasis is rare in childhood. A particular etiology has appeared over the last few years in connection with unusual physiological situations. Three cases of cholelithiasis after ileal atresia or resection are presented in children of 1, 1, and 7 yr. Another case is presented after abdominal irradiation for Wilms' tumor and ileal resection in a child of 7. The pathogenesis is discussed, raising the question of the interruption of the enterohepatic circulation of bile salts.

Bile Acids and Salts↗
PubMed1975

Phosphorus depletion in children on long-term total parenteral nutrition.

The retention of nitrogen, calcium and phosphorus was studied in nine infants on total parenteral nutrition. The amounts of calcium, nitrogen and phosphorus were varied singly or simultaneously. The results demonstrate close interrelationships in the retention of these three elements. Not only the absolute amount of phosphorus perfused daily but also the amounts of nitrogen and/or calcium perfused simultaneously account for the phosphorus depletion that may lead to severe hypophosphatemia. The decrease in serum phosphorus concentration with a simultaneous fall of urinary phosphorus excretion to undetectable levels and a rise in urinary calcium output to 10 mg/kg/24 hours or more are warning symptoms of phosphorus depletion. Such a complication was observed in our first seven children on total parenteral nutrition. Phosphorus depletion can be prevented by using the following amounts of these elements in the perfusate: per 100 Kcal/kg/24 hours, 400 mg/kg/24 hours of nitrogen, 35 mg/kg/24 hours of calcium and 40 mg/kg/24 hours of phosphorus. With such a technique no phosphorus depletion was observed in any of the 63 subsequent patients whom we treated with total parenteral nutrition for periods varying from 20 days to 9 months.

Amino Acids↗