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Biomedical subjects

C Rey

Publications and source records attributed to C Rey.

At least 361 records · Page 20Linked to original sources
PubMed1981

[Hepatic angiosarcomas].

The authors describe three cases of hepatic angiosarcoma diagnosed at postmortem examination, two of them being associated to thorium dioxide. The low incidence of these tumors amongst the general population is commented upon, and an update is made on the factors involved in their appearance, with special mention of thorium dioxide. An analysis of the clinical picture of the disease is undertaken, emphasizing its diagnostic difficulties. A tentative diagnosis can be made on the basis of clear-cut epidemiological data and or the presence of increased radiological density over the liver, spleen and paraaortic lymph nodes in the cases associated to thorium dioxide. Two of the reported patients presented hemolytic anemia, and disseminated intravascular coagulation, respectively; these findings, although nonspecific, may suggest the diagnosis in the presence of a toxic clinical picture or one of the above mentioned factors. The diagnosis should be made by the usual techniques utilized clinically to detect space occupying lesions within the liver. The evolution of such patients is rapidly progressive, with a fatal outcome within three to six months after beginning of symptoms.

Aged↗
PubMed1981

In vitro and in vivo binding of S-adenosyl-L-homocysteine to membranes from rat cerebral cortex.

Membranes from rat cerebral cortex are able to bind S-adenosyl-L-homocysteine (SAH) with a KD of 5 . 10(-7) M and n of 170 pmol/g fresh tissue (i.e. 20 mg protein). The binding is enhanced by Mg2+ and Ca2+ but not K+ and Na+. gamma-Aminobutyric acid, diazepine, noradrenaline and alpha antagonists are without any effect; S-adenosyl-L-methionine, adenosine and adenosine triphosphate inhibit SAH binding. Linkage with an adenosine receptor has not been expressly demonstrated by our method. SAH binding proteins are more abundant in the crude synaptosomal pellet (P2). A similar fixation seems to occur on brain membranes after [3H]SAH administration to rat. The binding might be linked to a methylase activity or an adenosine receptor.

Adenosine↗
PubMed1980

[Prostaglandins].

Explore the source record for details and available documents.

Heart Conduction System↗
PubMed1979

[Systemic lupus erythematosus induced by anticonvulsivant drug (author's transl)].

A 20-year-old patient with previous history since 9 years of age of epileptic crises, was followed since then by anticonvulsivant therapy. Eight months before her admittance to the hospital ethosuximide was added to the anticonvulsivant treatment with good results. The development of fever, pain in the joints, and pleuropericarditis decided her admittance, being the clinical evaluation analytically and immunologically compatible with a systemic lupus erythematosus. The discontinuance of the anticonvulsivant medication determined at the end of the 3rd week the clinical and analytical recovery of the patient. The immunological study was normal after 3 months. The addition of other anticonvulsivant drugs, without having modified the normal condition of the patient, establishes a cause-effect relationship after the administration of ethosuximide. The infrequency of this observation is commented on, and the present knowledge of the possible mechanisms implicated in the drug-induction of a systemic lupus erythematosus is discussed.

Adult↗
PubMed1979

[Pheochromocytoma and sudden death (author's transl)].

Five cases of pheochromocytoma are described in which sudden death was the form of the initial clinical presentation in almost all of them. After a brief review on the history and the incidence of the tumor within the general population, diverse cases are analyzed from a clinical point of view and in relation to the data appeared in the literature. In the analysis of the symptoms emphasis is placed on the important psychomotor manifestations which are present in the majority of those patients and which causes serious difficulties in the initial diagnosis. All of the patients showed signs of shock at the time of being observed or during the course of this observation, and in the majority of them the presence of acute pulmonary edema was confirmed; facts which we attribute to an initial hypertensive episode associated to a left heart failure. The onset of the crisis in two patients was related to known triggering factors: anesthesia and sulpiride. In other two patients associated conditions were diagnosed: medullary carcinoma of the thyroid gland in one of them, and cystic necrosis of the middle layer of the aorta in the other.

Adult↗