A comparison of doctor and computer interrogation of patients.
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Computers↗
Biomedical subjects
C R Evans
Publications and source records attributed to C R Evans.
Effect of a hot milk drink on movements during sleep.
The effects on sleep of a hot drink of milk and Horlicks were compared with those of hot water taken before retiring by medical student volunteers. Horlicks reduced the number of small movements made during sleep.
Adult↗
Effect of presenting novel verbal material during slow-wave sleep.
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Association↗
Attention as a concept in neurophysiology.
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Animals↗
Effect of humming on the visibility of a stabilized retinal image.
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Afterimage↗
Binocular depth perception of "Julesz Patterns" viewed as perfectly stabilized retinal images.
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Afterimage↗
Further studies of pattern perception and a stabilized retinal image: the use of prolonged after-images to achieve perfect stabilization.
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Adaptation, Ocular↗
Fragmentation phenomena associated with binocular stabilisation.
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Afterimage↗
Oculomotor function and the alpha activation cycle.
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Electroencephalography↗
A study of the effect of perfect retinal stabilization of some well-known visual illusions, using the after-image as a method of compensating for eye movements.
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Afterimage↗
Prolonged excitation in the visual cortex of the cat.
Intense light flashes produce maintained increased in cortical activity not dependent on continuous excitation from the retina.
Animals↗
An unexpected artefact in the human electroencephalogram concerning the alpha rhythm and the orientation of the eyes.
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Electroencephalography↗
Human dream processes as analogous to computer programme clearance.
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Computers↗
Assay of residual organic solvents in topiramate drug substance by capillary gas chromatography.
The analysis of residual organic solvents (methanol, ethanol and toluene) in topiramate drug substance was investigated. Topiramate is a potent anticonvulsant drug under clinical evaluation. The drug is recrystallized from ethanol denatured by either methanol or toluene, and each residual solvent is controlled at 0.1% (w/w) level. A capillary gas chromatography (GC) method described in this manuscript utilizes a DB-WAX, 1 micron thick, 30 m x 0.53 mm i.d., column. Since topiramate is a thermally labile compound, the selection of the proper injector temperature is critical to the success of the analysis. The injector temperature was set at 120 degrees C to prevent degradation. The initial oven temperature was set at 55 degrees C for 8 min and programmed at a rate of 30 degrees C min-1 to a final temperature of 160 degrees C for 11 min. Helium was used as a carrier gas. The sample solvent selected was dimethylformamide pretreated with molecular sieves to remove trace amounts of alcohols that may interfere with the assay. The method was validated to be specific, linear, precise, sensitive, rugged and showed excellent recovery.
Anticonvulsants↗