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Biomedical subjects

C R Daniel

Publications and source records attributed to C R Daniel.

At least 37 records · Page 2Linked to original sources

Chronic paronychia and onycholysis: a thirteen-year experience.

We report here on two retrospective studies conducted between 1982 and 1995 in 137 patients with clinical evidence of chronic paronychia or onycholysis. The purpose of the studies was to determine what factors played a role in these nail disorders. The culture results indicated that yeast commonly grew from the cultured material. Significant contact irritant exposure was frequently found. These findings and our experience suggest that the resolution of chronic paronychia and onycholysis depends on avoiding exposure to contact irritants and on appropriate treatment of any underlying fungal infection. To accomplish this latter goal, it is important to select a broad-spectrum antifungal agent that is effective against yeasts as well as other fungal pathogens.

Adolescent↗

Onychomycosis update.

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AIDS-Related Opportunistic Infections↗

Cutaneous manifestations of fungal infection.

Fungal infection of the skin and subcutaneous tissue may result from either direct contact or inoculation injury (primary infection) or from hematogenous spread from a primary focus of disease (secondary infection). The parainfectious lesions of erythema nodosum and erythema multiforme are manifestations of the host's immune response to the invading fungus, particularly Histoplasma capsulatum and Coccidiodes immitis. In some patients, skin lesions may be the only sign of a systemic fungal infection, and prompt recognition of these lesions may facilitate early diagnosis and treatment. This article first addresses the pathogenesis, host defenses, and diagnosis of fungal skin infections. The specific cutaneous manifestations of the superficial, cutaneous, subcutaneous, and systemic mycoses are then reviewed.

Antifungal Agents↗

The spectrum of nail disease in patients with human immunodeficiency virus infection.

There are no known pathognomonic nail signs of human immunodeficiency virus (HIV) infection. However, several presentations should increase the index of suspicion. (1) Proximal white subungual onychomycosis or superficial white onychomycosis, especially of the fingernails, is present. Trichophyton rubrum appears to cause both most commonly in HIV-infected patients. Periungual dermatophyte involvement and involvement of all 10 fingernails is unusual in non-HIV-infected persons. (2) Candida is a primary pathogen of the nail bed and nail plate especially if many nails are involved. (3) A destructive, almost granulomatous-like psoriatic involvement of the nails is present. (4) Squamous cell carcinoma of the nail bed in a young adult. There are no clinical trails to confirm the efficacy of therapy mentioned in this article. The treatment suggestions are empirical and are the personal views of the authors.

Candidiasis, Cutaneous↗

Basic nail plate avulsion.

Correct partial or total nail plate avulsion may be performed in the physician's office. The author recommends certain preoperative, operative, and postoperative procedures that may help assure a more successful outcome.

Anesthesia, Local↗

Onycholysis: an overview.

Onycholysis is commonly seen in dermatological practice. To treat this disorder properly, it must be approached in an orderly manner. The cause must be ascertained and eliminated, if possible. General treatment principles and specific recommendations for diagnosis and therapy have been made.

Humans↗

Nail damage secondary to a hair spray.

Nail abnormalities secondary to contact with cosmetic preparations are well documented in the literature. This report documents a case of nail dystrophy apparently secondary to use of a hair spray.

Female↗

The nail.

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Biopsy↗

Bilateral popliteal arteriovenous fistulas.

An unusual case of bilateral popliteal arteriovenous fistulas is reported. The patient reported right leg discomfort and swelling 1 month after multiple gunshot wounds to both legs; the left leg was asymptomatic. Arteriography demonstrated AV fistulas in both popliteal arteries. The importance of a high index of suspicion in making the diagnosis is emphasized.

Adult↗

Tinea unguium.

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Foot Dermatoses↗

Tinea unguium.

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Griseofulvin↗

Nail micronizer.

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Humans↗

An approach to initial examination of the nail.

A systematic method of examining nail disorders is important. A patient questionnaire (sample provided) and a basic method of categorizing various problems are helpful tools. Thorough investigation usually yields a diagnosis.

Humans↗