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Biomedical subjects

C R Archer

Publications and source records attributed to C R Archer.

At least 37 records · Page 2Linked to original sources

Extradural lipomatosis simulating an acute herniated nucleus pulposus. Case report.

A 48-year-old laborer presented with a 1-year history of low-back pain radiating into the posterior aspects of both thighs. Two weeks before admission, acute exacerbation resulted in signs and symptoms of compressive radiculopathy at L-5. Myelography revealed concentric constriction of the lower thecal sac due to abundant fat, as shown by computerized tomography. Laminectomy produced immediate relief of pain. The significance of these findings and a review of the literature are presented.

Adolescent↗

Hyperphagia and obesity. Relationship to medial hypothalamic lesions.

Progressive left hemiparesis followed by face and trunk cutaneous vasodilation and hyperphagia developed in a 28-year-old man. He began eating five to six meals a day and gained 16 kg in 60 days. Computed tomography disclosed a neoplastic lesion involving the midline via the hypothalamus and reaching the contralateral lenticular nucleus. Findings from endocrine studies, including thyroid-stimulating hormone, growth hormone, prolactin, and cortisol serum levels, were normal. Hyperphagia and consequent obesity were associated with bilateral destruction of the ventromedial hypothalamic area; cutaneous vasodilation was related to involvement of the preoptic area.

Body Weight↗

Case report. Aphasia in thalamic stroke: CT stereotactic localization.

We present a patient in whom dysphasia followed suddenly upon an apparently discrete thalamic infarct proven by computed tomography (CT). Detailed psychometric data of the patient's speech and memory disorder obtained during the acute and chronic stages were correlated with the evaluation of a focal thalamic lesion as demonstrated by serial CT. The findings and deductions drawn from selective reports in the literature form the basis of this presentation.

Aphasia↗

High resolution computed tomography in the staging of carcinoma of the larynx.

The normal anatomy of the larynx as displayed on computed tomography is illustrated. Pathological alterations in patients with carcinoma of the larynx are depicted and discussed. Computed tomography (CT) is recommended as the initial radiological procedure when additional diagnostic information is required to supplement the findings of laryngoscopy. CT provides information regarding deep penetration of tumor, including cartilaginous invasion, and about the inferior extension of neoplasm, including the subglottic area. This knowledge helps to determine whether conservative surgery as opposed to total laryngectomy is possible.

Humans↗

Staging of carcinoma of the larynx: comparative accuracy of ct and laryngography.

The accuracy and clinical usefulness of both computed tomography (CT) and laryngography were evaluated in 30 patients with carcinoma of the larynx. The radiologic results were correlated with the surgical and pathologic findings. The accuracy in determining tumor compartmental localization (supraglottic, glottic, or subglottic) was as follows: CT provided the correct diagnosis in 26 cases. There were three false negative and one false positive diagnoses. Laryngography provided the correct diagnosis in 19 cases. There were six false negative and six false positive diagnoses. In virtually all cases, CT provided information equivalent to or more accurate than laryngography. CT is recommended as the radiologic procedure of choice when additional diagnostic information is required to supplement the findings of laryngoscopy in determining the feasibility of conservation surgery.

Diagnostic Errors↗

Visual function of the extrageniculo-calcarine system in man: relationship to cortical blindness.

A 72-year-old woman, blind for more than two years, had normal evoked potentials to visual stimulation. Destruction of both areas 17 and relative preservation of areas 18 and 19 was demonstrated. We concluded that in the presence of bilateral destruction of area 17, visual evoked potentials are mediated by extrageniculocalcarine pathways to secondary visual cortices, but this system is not capable of providing conscious visual perception in humans.

Aged↗

Ethmoidal fibro-osseous lesion in a child. Diagnostic and therapeutic problems.

A 4-year-old Caucasian male presented with marked proptosis of the right eye of 3 months' duration. A large soft tissue mass occupied fully the right ethmoid sinus; radiologic evidence of extensive bone destruction suggested a malignant tumor. Unexpectedly, a biopsy of the ethmoid tumor was interpreted as benign. Over the next 2 months, this lesion progressed rapidly, with further bone destruction and extension into the anterior cranial fossa. The histopathologic features of a resection specimen were so variable that a wide range of diagnoses was offered by several consultants who examined the material. This lack of agreement among experts in the field of bone diseases considerably influenced the treatment program selected for this patient.

Bone Neoplasms↗

Evaluation of laryngeal cartilages by computed tomography.

Computed tomography of the larynx was performed in 21 patients and 3 anatomic specimens for evaluation of laryngeal cancer. Special attention was directed to the appearance of the laryngeal cartilages in both the normal and abnormal examinations in order to establish criteria for cancerous invasion. The problem presented by the normal nonuniformity of density of the cartilages is discussed in detail.

Adult↗

Infundibula may be clinically significant.

An infundibulum at the origin of the posterior communicating artery is observed to such an extent that it provokes little interest or comment. Although considered preaneurysmal by some, no serious consideration is given to its surgical removal. We present a patient with a subarachnoid hemorrhage, a middle cerebral artery aneurysm, and bilateral posterior communicating artery infundibula to draw attention to the importance of the infundibulum in certain circumstances.

Brain↗

Computer tomography of the larynx.

Evaluation of computed tomography of the normal larynx has been performed utilizing corresponding tomographic and anatomic planes. The transaxial, coronal, and sagittal planes have been evaluated. While all three planes have distinct potential diagnostic value, the transaxial plane offers a unique view of laryngeal structures not afforded by any other technique. It is hoped that diagnostic criteria developed in this study will prove applicable to the evaluation of clinical laryngeal disease.

Humans↗

Evaluation of laryngeal cancer by computed tomography.

Six cases of laryngeal cancer have been examined by computed tomography. The findings were correlated with those obtained by laryngoscopy and in five cases by pathological examination of the surgical specimens. Computed tomography accurately delineated the extent of tumor involvement of the laryngeal and paralaryngeal soft tissues. The diagnosis of involvement of the laryngeal cartilages presents some problems, which are discussed.

Aged↗