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Biomedical subjects

C Petrescu

Publications and source records attributed to C Petrescu.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[Use of the excluded jejunal loop for resolution of some accidents in surgery of ulcers and the biliary tract].

The specific risks of certain procedures applied in surgery of the bile ducts and duodenal ulcers are discussed (Lehey catheterism, retrograde cholecystectomy with primary severing of the cystic duct for cholangiography). Three accidental lesions of the common bile duct were successfully solved by anastomosis of the left hepatic, right hepatic and respectively commen hepatic duct with the excluded jejunal loop by the Roux-Y method. The importance of intraoperative cholangiohepatography for established immediately the biliary areas that have to be shunted into the excluded loop, is emphasized.

Aged↗
PubMedDate not supplied

Study on the prevalence of eccentric and concentric atherosclerotic plaques in various segments of the coronary arterial tree, in unselected and selected Bucharest population samples.

A study was carried out on the prevalence and distribution of eccentric and concentric atherosclerotic plaques in the coronary arterial tree of 916 unselected apparently healthy subjects who died from accidents and of 150 selected patients who died from coronary heart disease. The results show that the percentages of eccentric and concentric plaques vary with age, sex, anatomical branching pattern and cause of death; there are also differences between major coronary arteries and main branch vessels. In addition to eccentric and concentric plaques, we revealed the existence of mixed (both eccentric and concentric) plaques, mainly located at branch points.

Accidents↗
PubMedDate not supplied

Prevalence of thick intimas and of obstructive lesions in the vessels supplying the conduction system of the heart.

A study of the prevalence of thick intimas and of obstructive lesions in the vessels supplying the conduction system of the heart (first septal artery, sinus node artery, atrioventricular node artery, posterior descending artery) was carried out on both non-hospitalized and hospitalized subjects. A total of 932 cases aged 6 to 55 years were investigated. The age period of the onset of both intimal thickenings and atherosclerotic plaques, the percent of cases with intimal thickenings and atherosclerotic plaques in successive age groups and the highest value of the intima thickness/media thickness ratio, were recorded. Comparative data are presented between apparently healthy subjects who died of accidental causes and patients of similar age and sex, who died of coronary heart disease. Sudden cardiac death cases are presented showing as the most important lesion the obstruction of the sinus node and atrioventricular node arteries. The results point to a need for a more frequent routine examination of the vessels supplying the conduction tissue of the heart.

Adolescent↗
PubMedDate not supplied

Role of thrombosis in the onset, progression and obstructive character of coronary atherosclerotic plaques.

A study was carried out on the role of successive microthrombi incorporation and intramural thrombi formation in the onset, progression and obstructive character of coronary atherosclerotic plaques. The coronary arterial tree of 836 apparently healthy subjects 1 to 50 years old who died of accidental causes was investigated. The onset of coronary atherosclerotic plaques having as precursors thrombi could be detected in 10% of advanced lesions. The left anterior descending artery appeared as the vessel of the coronary arterial tree the most susceptible to plaque development induced by thrombi and to the occurrence of thrombi on preexisting plaques. This occurrence of thrombi on preexisting plaques was recorded in 48% of subjects aged 46 to 50 years and was followed by a severe luminal narrowing in the major coronary arteries.

Adolescent↗
PubMedDate not supplied

A further study on the influence exerted by vascular geometry on coronary atherosclerotic involvement.

A further study was carried out on the relationship between coronary artery geometry and atherosclerotic involvement. The results show that: a) the coronary artery geometry may expose an individual at an early age to an increased risk for developing atherosclerotic lesions; b) the presence, in the coronary arterial bed of vessels with large diameters (greater than 2 mm) and the succession of numerous branching points also appeared as atherogenic conditions; c) the type of atherosclerotic lesion (proliferative, insudative, necrotic, lipid-rich) was, in our material strongly influenced by the geometry of branch sites.

Adolescent↗
PubMedDate not supplied

Prevalence of the "normal" aspect of the coronary arteries in an unselected population sample of Bucharest aged 1-60 years.

The coronary arterial trees obtained from 640 subjects 1-60 years old were studied grossly and by light microscopy, including morphometric methods. The highest values of of the ratio intima/media thickness were recorded in successive age groups, with special reference to those topographic sites where this ratio acquired an abnormal value. The percent of children, adolescents, young and mature adults free of atherosclerotic plaques, gelatinous lesions and intima necrotic areas, fatty streaks and intramural thrombi was also evaluated. An association was revealed between the number of subjects with anatomically normal coronary arteries and the presence of the common type of distribution of the coronary arteries in these subjects.

Aging↗
PubMedDate not supplied

Atherogenic anatomical patterns of coronary arteries branching related to cardiac and non-cardiac causes of death.

A gross and light microscopic study carried out on 102 selected male subjects aged 51-70 who died of ischemic heart disease and on 102 selected, male subjects of similar age, who died of noncardiac causes revealed that: in subjects who died of ischemic heart disease the prevalence of atherogenic deviations from the common type of distribution of the coronary arteries was 2-4 times greater than in subjects who died of non-cardiac causes; subjects who died of ischemic heart disease, with the atherogenic deviations from the common tape of distribution of the coronary arteries showed an increased number of stenotic atherosclerotic plaques and a particular propensity to "clustering" of these lesions, predominantly around branch mouths.

Aged↗
PubMedDate not supplied

A method which improves anatomo-clinical correlations in ischemic heart disease.

A study carried out on 595 unselected subjects aged 21-55 years who had died of accidental causes and on 56 selected patients who had died of myocardial infarction showed that the light microscopic examination of coronary branch vessels led to an obvious improvement of anatomo-clinical correlations in ischemic heart disease. These branch vessels included atherosclerotic plaques in 51% of unselected subjects 51-55 years old, dead of accidents and in 73% of selected patients dead of myocardial infarction. Severe stenotic plaques of possible clinical significance were found in 14% of subjects dead of accidents and in 48% of patients dead of myocardial infarction. In these cases the atherosclerotic involvement in the major coronary arteries (left anterior descending, circumflex and right coronary arteries) did not reach the level of possible clinical significance (greater than or equal to 75% reduction of the vessel diameter). Several examples emphasize the importance of stenotic lesions in the first diagonal, first septal, posterior descending, left marginal and right marginal vessels, as well as in the vessels supplying the sinoatrial and atrioventricular nodes for an adequate anatomo-clinical correlation in ischemic heart disease.

Accidents, Traffic↗