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Biomedical subjects

C Perrin

Publications and source records attributed to C Perrin.

At least 37 records · Page 2Linked to original sources
PubMed1991

Posture in basketball players.

Static and dynamic posturography was recorded in eleven professional national basketball players (complete team). This sport requires balance and skill and is practiced by tall subjects (average height: 197 cm) with a history of 10 to 15 tibio-tarsal sprains. In static tests, with eyes open or closed, the way was similar between controls and players, while the area was increased for the latter. Area increment could be related to the history of ankle trauma reported by these subjects. In toes up dynamic tests, the latency of the first response (short latency response-myotatic reflex) was shorter in players. Data provided by national charts were used to compare posturography performance and player's skill. The best player who also ranks high in the national chart, has distinctive results in static posturography, with almost no difference when the test is performed with closed eyes.

Adolescent↗
PubMed1990

Lingual fibrosarcoma induced by 7, 12-dimethylbenzanthracene in the rat.

A single injection of 5 mg of 7, 12-dimethylbenzanthracene (DMBA) resulted in a high incidence of lingual fibrosarcoma in 67 Wistar rats. No metastases were found. We studied the influence of age and sex on the incidence, latency of tumors, loss of weight and the spontaneous survival of animals. The method described offers an experimental model for the study of cachexia resulting from upper digestive and respiratory tract cancer.

9,10-Dimethyl-1,2-benzanthracene↗
PubMed1990

[Skull vault bone graft in augmentation septorhinoplasty].

We describe our technique of augmentation rhinoplasty with bone grafting. Degloving is used as the surgical access in collapsed noses, and midcolumellar incision allows further buildup of the nasal contour. A V cutting is made on the dorsum to receive the graft. A split skull graft is taken with a drill and an osteotome. The sculpted bone implant is maintained in position with a miniaturized screw. We compare various bone grafts and types of surgical access.

Bone Transplantation↗
PubMed1990

[Use of the Galea flap in ORL].

We use the Galeal pericranial flap with the temporal vessels. Its high vascular content and its low esthetic and functional after effects are very interesting. The dissection between the outside of the flap and the subcutaneous tissue is difficult. The Galeal epicranial flap can cover wounds of orobuccopharynx, otopoiesis and loss of facial substance. We use it for arranging open technic and also for sealing the skull base.

Humans↗
PubMed1989

[Value of anthropometric techniques in pediatric otology].

The recurrent and severe infections of the ENT region during childhood are frequently related to cranio-facial malformations or/and deficiency of the immune system. The cranio-facial abnormalities are at risk to be complicated by transmission deafness either primary or secondary through recurrent middle ear infections. In our pediatric out-patient clinic, most of the patients suffering severe recurrent ENT problems show variable malformations: abnormal implantation or shape of the external ear, a microretrognathism, cervical or facial branchial fistulae, high or ogival palate with anomalies of the dental occlusion or a bifid uvula. All these abnormalities share their origins in a pathological development of the first branchial arch. These developmental anomalies may directly lead to deafness (especially due to an abnormal middle car ossicular development since they are derived in part from the first arch). They may also favor secondary pathologies (middle ear otitis, abnormal soft palate). Moreover the development of the immune system is also dependent of a normal function of the endoblastic epithelium of the pharyngeal pouches which is a part of the branchial system. Immune dysfunctions may therefore accentuate the severity of the ENT Infections.

Anthropometry↗
PubMed1989

[Elevated levels of plasma 4-ene steroids in a case of congenital deficiency of 3 beta-hydroxysteroid dehydrogenase].

Plasma hormones have been evaluated from birth to six months in a boy with male pseudohermaphroditism due to congenital 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) deficiency. At birth, plasma 17-hydroxyprogesterone (17-OHP) was slightly elevated while cortisol was within the normal range. Both 17-OHP and testosterone (T) were increased the fifth day. At the age of 2 months, only the baseline level of 17-hydroxypregnenolone (17-OH5P) was slightly elevated and the diagnosis of 3 beta-HSD deficiency was established in view of the excessive response of 17-OH5P and dehydroepiandrosterone (DHA) to Synacthen administration. There was an important increase of T and dihydrotestosterone in response to chorionic gonadotropin (hCG) administration while no significant variation of the other studied steroids was observed. These results suggest that the determination of plasma 17-OH5P seems to be the best tool to diagnose congenital 3 beta-HSD deficiency. The increase of 17-OHP is the result of 17-OH5P conversion in peripheral tissues. Though T response to hCG is rather normal, a partial testicular deficiency of 3 beta-HSD cannot be excluded. The ambiguous genitalia observed in this boy with normal plasma T levels might suggest that T production might have been deficient at the time when urethral-fold fusion occurred.

17-alpha-Hydroxypregnenolone↗
PubMed1989

[Static and dynamic posturography. Application to a population of young athletes].

The authors used a vertical force platform fitted with 4 pressure gauges (Societe Toennies). The static regime provides the statokinesigram, the lateral and sagittal stabilograms and their Fourier transformations. Information is collected with the eyes open and closed, thereby allowing the Romberg quotient to be determined. In the dynamic regime, the platform unexpectedly tilts to a toes-up position (4 degrees at a rate of 50 degrees/s). The activity of the tibialis anterior and soleus muscles is recorded by integrated electromyography. The early soleal response, provoked by the myostatic reflex, is followed by later responses due to the vestibulo-spinal reflex. These various parameters were recorded in young athletes and the obtained tracings are commented on.

Adolescent↗
PubMed1989

[Endodontic anatomy of lower premolars--apropos of 669 cases].

Six hundred sixty nine human mandibular first and second premolars were collected (extracted) and studied. We made roentgenographic studies, sections of extracted teeth. Comparisons with the findings of other investigators were made in regard to the number of roots and number of root canals (in different tables).

Bicuspid↗
PubMed1989

[Fatal cerebral aspergillosis in acute megakaryoblastic leukemia].

A 13 year-old girl was diagnosed as having acute megakaryoblastic leukemia. A serious infectious syndrome appeared during the chemotherapy, not improved by broad spectrum antibiotic therapy. A pulmonary aspergillosis was diagnosed one month later by a second bronchoalveolar lavage. A treatment with Itraconazole, a new antifungal triazole, was started. Despite this treatment, the child died after 3 days. Death was due to multiple aspergillus abscesses disseminated in the brain leading to coma and transtentorial herniation. Autopsy confirmed the cerebral aspergillus abscesses and showed also the dramatic dissemination of aspergillosis in the body. Diagnosis and treatment to aspergillosis in immunosuppressed patients should be made early to improve prognosis.

Adolescent↗
PubMed1989

[Cayler's cardio-facial syndrome. Apropos of 19 cases].

Hypoplasia of the depressor angulae oris muscle can be detected in the crying newborn by an asymmetry of the facies, and it must be differentiated from facial palsy. Asymmetry of the facies during crying spells associated with a congenital cardiac abnormality constitutes the Cayler's cardiofacial syndrome. Nineteen cases of this syndrome are reported. A wide spectrum of congenital heart defects of varying severity was observed, ventricular septal defect being the most common along with frequent malformations involving systems and organs other than the heart.

Adolescent↗
PubMed1989

[Cervical spondylodiscitis. A rare complication of intubation].

The authors present two cases of cervical spondylodiscitis occurring following intubation. The most probably mechanism was direct contamination of the inter-vertebral disk through a lesion of the posterior pharyngeal wall, but other possible mechanisms for the spread of infection are discussed. This very rare complication should be borne in mind and routinely sought when there is persistence of cervical pain following intubation.

Aged↗
PubMed1988

[A specific etiology of radiologic cannon balls: sarcoidosis. Apropos of a case].

A distinctive form of sarcoidosis is reported. A young woman, without any past medical history, presented with a cannon-ball radiographic appearance and a fever, suggesting an infection or underlying neoplasm. A lung biopsy gave the diagnosis of sarcoidosis after negative fibreoptic bronchoscopy, bronchial lavage and needle biopsy. This macronodular form of sarcoidosis is known but rarely described. There was a favourable clinical and radiological outcome, which occurred spontaneously.

Adult↗
PubMed1988

[Otologic signs and early diagnosis of Turner syndrome. Reevaluation of 30 cases].

In most occasions the Turner's syndrome is diagnosed on the basis of severe growth retardation. But the possibility of an effective treatment of short stature requires earlier a diagnosis. Among the other signs, the importance of ORL signs is underestimated. A group of 30 patients has been analysed to determine their precise extension. The external ears are frequently prominent, low-set and/or posteriorly rotated. Frequency and chronicity of otitis media is highlighted by hypoacousy of the transmission type. The perception pathology is far less common and seems being independent of middle ear pathology. A abnormal development of the 1st branchial arch is likely to explain the auricular pathology in view of the frequently associated anomalies of the palate and the dental articulation. One must clearly consider the diagnosis of Turner syndrome in the case of chronic auricular pathology associated with low linear velocity in a young girl allowing for earlier diagnosis.

Adolescent↗
PubMed1988

[Subcutaneous rhabdomyosarcoma in children. Clinical, immunologic and ultrastructural aspects].

Embryonal rhabdomyosarcoma is the most frequent of tissue sarcomas in children. Its location in the subcutaneous tissue makes it a dermatological diagnosis. In childhood, the exact histological type of the tumour, sometimes difficult to determine, is absolutely necessary since prognosis and treatment differ according to the histogenetic form. Rhabdomyosarcoma is rare in adults. One must rule out malignant pleomorphic histiocytoma which has a more favourable prognosis. Among the antisera recently made available, those directed against desmin, foetal skeletal myosin and/or specific skeletal muscle myofilament seem to be most useful when associated with the anti-myoglobin antibody.

Child↗