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Biomedical subjects

C Ori

Publications and source records attributed to C Ori.

At least 55 records · Page 3Linked to original sources

The treatment of hemifacial spasm with percutaneous radiofrequency thermocoagulation of the facial nerve.

The authors present their first results with the treatment of hemifacial spasm by controlled percutaneous thermocoagulation of the facial nerve. Seven patients have been treated to date with good immediate results on the movements, although a slight paresis of the homolateral facial musculature, aesthetically acceptable, persists after treatment. A long-term follow-up at more than 10 months was achieved in only 3 patients, who showed a complete regression of the spasm with partial disappearance of the facial hemiparesis.

Adult↗

Percutaneous thermocoagulation for sphenopalatine ganglion neuralgia.

The authors describe percutaneous radiofrequency (rf) thermocoagulation of the sphenopalatine ganglion used to treat seven patients with sphenopalatine ganglion neuralgia. The procedure was effective in relieving pain, without significant side-effects. All the patients have actually been free of pain during a follow-up of 6-28 months. The surgical technique and the rationale for its use are pointed out.

Adult↗

Extraordinary postmortem stability of kappa opioid receptors in guinea-pig brain.

Postmortem delay can be an important variable in biochemical studies on autopsy tissue. We subjected guinea-pig brains to gradual cooling, simulating temperature conditions of human postmortem brains, in order to assess the sensitivity of kappa receptors to postmortem degradation. Kappa receptor specific binding was defined as the (-)-[3H]ethylketocyclazocine bound in the presence of 100 nM D-ala2-D-leu5-enkephalin and 30 nM morphine. Postmortem delays of up to 16 h did not alter the affinity or density of kappa binding sites. The remarkable stability of kappa receptors may greatly facilitate the study of this opioid receptor subtype in human brain.

Analgesics, Opioid↗

Accidental high voltage electrocution: a rare neurosurgical problem.

The authors describe a case of accidental electrocution from a high voltage current in a young worker, who was struck by the electric shock in the mid-occipital region. The case is especially interesting due to the improbability of anyone surviving after receiving a shock of more than 1000 V., and to the development of bilateral parieto-occipital haemorrhagic infarction with spastic paraparesis, directly caused by the high voltage current and not indirectly by heat generation or secondary head trauma.

Adult↗

Combined thermocoagulation of the 5th and 9th cranial nerves for oral pain of neoplastic aetiology.

The authors report their limited but interesting experience in the treatment of intractable oral pain employing the technique of percutaneous radiofrequency thermocoagulation both of the trigeminal and glossopharyngeal nerves. The use of combined percutaneous thermolesions for cancer pain is rarely described in the literature. Immediate and long-term results confirm the usefulness of this surgical procedure.

Aged↗

Effects of isoflurane anesthesia on local cerebral glucose utilization in the rat.

The effect of isoflurane anesthesia on local rate of glucose utilization was investigated in the rat brain by means of the autoradiographic 14C-2-deoxyglucose method. Local cerebral glucose utilization (LCGU) was measured in 26 neuroanatomic structures of awake and isoflurane-anesthetized rats. Isoflurane anesthesia (1.5% inspired) caused both increases and decreases in LCGU. Significant reductions were found in all cortical areas examined and in primary sensory relay nuclei of central visual and auditory pathways. Among regions of the extrapyramidal motor system, LCGU was increased in substantia nigra pars compacta, and decreased in cerebellum, red nucleus, and ventral thalamus. Large increases in LCGU were observed in some structures of the limbic system such as the medial habenulo-interpeduncular system and the CA3 field of hippocampus. LCGU was significantly reduced by isoflurane in the CA1-CA2 field and dentate gyrus of hippocampus. These results are similar to previous findings on the LCGU response to other inhaled and intravenous anesthetics and further confirm the regional specificity of the effects of anesthetics on brain metabolism.

Anesthesia, Inhalation↗

Head injuries and their early management. An account of one year's experience.

We report 298 patients admitted to the Neurosurgical unit of the University of Padua during one calendar year. We divided the patients into two groups. "in coma" and "not in coma", and analyze their data records. The time between injury and admission to a neurosurgical centre is important for therapy as well as for transport. The necessity of an "Admission Chart" is emphasized.

Adolescent↗

Admission chart as a protocol for reception and first management of head injuries.

In order to gather fundamental information about the reanimative, diagnostic, and therapeutic measures concerning head-injured patients, we propose the introduction of an "Admission Chart". This Chart ought to accompany patients from the first contact with Accident-Emergency Medical Staff to arrival at a specialized Centre.

Craniocerebral Trauma↗

Selective percutaneous thermolesions of the ninth cranial nerve by lateral cervical approach: report of eight cases.

Percutaneous radiofrequency thermolesion of the petrous ganglion at the jugular foramen was employed for the treatment of glossopharyngeal neuralgia in eight cases, three with essential and five with symptomatic pain from oropharyngeal cancer. Because of its technical simplicity, the lateral cervical approach was preferred to the anterior lateral approach. Immediate and subsequent surgical results were satisfactory. No neurological complication was noted, except for transitory bradycardia and hypotension during the procedure.

Adult↗

Percutaneous glossopharyngeal thermocoagulation complicated by syncope and seizures.

We describe the case of a patient who, during the percutaneous thermocoagulation of the petrous ganglion of Andersch, suffered a serious vagal response resulting in cardiac arrest, collapse, and generalized convulsions. Notwithstanding such major symptoms, the postoperative examination revealed no lesions of the vagus nerve and the glossopharyngeal lesion was shown to be isolated and selective.

Adult↗